GPNMB

Gene Symbol	GPNMB
Entrez Gene	10457
Alt Symbol	HGFIN, NMB
Species	Human
Gene Type	protein-coding
Description	glycoprotein (transmembrane) nmb
Other Description	glycoprotein NMB|glycoprotein nmb-like protein|osteoactivin|transmembrane glycoprotein HGFIN|transmembrane glycoprotein NMB
Swissprots	A4D155 Q6UVX1 Q8N1A1 Q14956
Accessions	AAN59897 AAP22336 AAP22337 EAL24259 EAW93781 EAW93782 EAW93783 EAW93784 Q14956 AF322909 AAG42839 AI952217 AJ505015 CAD43718 AK292078 BAF84767 AK296779 BAG59357 AK297031 BAG59559 AK297051 BAG59577 AK297055 BAG59580 AK297803 BAG60141 AK303071 BAG64187 AK304671 BAG65446 AK312279 BAG35208 AY359124 AAQ89481 BC011595 AAH11595 BC025297 BC032783 AAH32783 BM750843 BT007074 AAP35737 BU537639 CD105306 DQ892084 ABM83010 DQ895277 ABM86203 X76534 CAA54044 XM_005249578 XP_005249635 NM_001005340 NP_001005340 NM_002510 NP_002501
Function	Could be a melanogenic enzyme. {ECO:0000250}.
Subcellular Location	Cell membrane; Single-pass type I membrane protein. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Detected at the cell surface in different types of cancers cells, including glioblastoma multiforme cells and most melanoma cell lines.
Tissue Specificity	Up-regulated in various cancer cells, including in glioblastoma multiforme. Expressed in many melanoma cells, as well as in tissue macrophages, including liver Kuppfer cells and lung alveolar macrophages, in podocytes and in some cells of the ciliary body of the eye (at protein level). Hardly detectable in healthy brain. {ECO:0000269|PubMed:16489096, ECO:0000269|PubMed:16609006, ECO:0000269|PubMed:7814155}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

GPNMB-Over-expression-Lysate - LY15045a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

GPNMB overexpression lysate - LY400379 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

GPNMB 293 Cell Lysate - 400405 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

Osteoactivin/GPNMB Overexpression Lysate (Native) - NBL1-11239 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

GPNMB Over-expression Lysate Product - GWB-2BF6E5 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

Human GPNMB / Osteoactivin HEK293 Cell Lysate (WB positive control) - 11305-H08HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human GPNMB / Osteoactivin HEK293 Cell Lysate (WB positive control) - 11305-H02HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human GPNMB Human Cells Transfected Lysate (positive control) (denatured) - orb174527 from Biorbyt Category Cell Lysate Prices $604.00 Sizes 300 μg Species Human

Human GPNMB Human Cells Transfected Lysate (positive control) (denatured) - orb173842 from Biorbyt Category Cell Lysate Prices $604.00 Sizes 300 μg Species Human

Panoply™ Human GPNMB Knockdown Stable Cell Line - CSC-DC006505 from Creative biogene Category Cell Line Species Human

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