PHF8

Gene Symbol PHF8
Entrez Gene 23133
Alt Symbol JHDM1F, MRXSSD, ZNF422
Species Human
Gene Type protein-coding
Description PHD finger protein 8
Other Description histone lysine demethylase PHF8|jumonji C domain-containing histone demethylase 1F
Swissprots Q7Z6D4 Q9HAH2 Q5JPS3 Q5JPS0 Q5JPR9 Q5VUJ4 Q5JPS2 Q5H9U5 Q9UPP1 B3KMV4 B7Z911
Accessions EAW93167 EAW93168 EAW93169 EAW93170 Q9UPP1 AB029034 BAA83063 AF091081 AAC72950 AK021696 BAB13877 AK022788 BAG51116 AK027229 AK304272 BAH14147 BC017720 BC042108 BC053861 AAH53861 BE676640 CR933612 CAI45929 DA458639 DB079048 XM_005261996 XP_005262053 XM_005261997 XP_005262054 XM_005261999 XP_005262056 XM_005262000 XP_005262057 XM_006724585 XP_006724648 XM_011530778 XP_011529080 NM_001184896 NP_001171825 NM_001184897 NP_001171826 NM_001184898 NP_001171827 NM_015107 NP_055922
Function Histone lysine demethylase with selectivity for the di- and monomethyl states that plays a key role cell cycle progression, rDNA transcription and brain development. Demethylates mono- and dimethylated histone H3 'Lys-9' residue (H3K9Me1 and H3K9Me2), dimethylated H3 'Lys-27' (H3K27Me2) and monomethylated histone H4 'Lys-20' residue (H4K20Me1). Acts as a transcription activator as H3K9Me1, H3K9Me2, H3K27Me2 and H4K20Me1 are epigenetic repressive marks. Involved in cell cycle progression by being required to control G1-S transition. Acts as a coactivator of rDNA transcription, by activating polymerase I (pol I) mediated transcription of rRNA genes. Required for brain development, probably by regulating expression of neuron-specific genes. Only has activity toward H4K20Me1 when nucleosome is used as a substrate and when not histone octamer is used as substrate. May also have weak activity toward dimethylated H3 'Lys-36' (H3K36Me2), however, the relevance of this result remains unsure in
Subcellular Location Nucleus. Nucleus, nucleolus. Note=Recruited to H3K4me3 sites on chromatin during interphase. Dissociates from chromatin when cells enter mitosis.

Rabbit anti-PHF8 Antibody, Affinity Purified - PLA0211 from Sigma-Aldrich

Prices $323.50
Sizes 100 µl
<B>Immunohistochemistry</B><BR/>Rabbit Anti-PHF8 Antibody, Affinity Purified: <B>Cat. No. PLA0211</B>: Detection of Mouse PHF8 by Immunohistochemistry. Sample: FFPE section of Mouse renal cell carcinoma. Antibody: Affinity purified Rabbit Anti-PHF8 (<B>Cat. No. PLA0211</B>) used at a dilution of 1:200 (1 μg/mL). Detection: DAB

PHD finger protein 8, ELISA Kit - MBS9328864 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 0.1ng/ml.
Range 0.625 ng/ml - 20 ng/ml.

PHD Finger Protein 8 (PHF8), ELISA Kit - MBS2019238 from MyBioSource

Category ELISA Kit
Prices $385.00, $575.00, $785.00, $3,210.00, $5,825.00
Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity Typically less than 0.118ng/mL.
Range 0.313-20ng/mL

ELISA Kit for PHD Finger Protein 8 (PHF8) - SEH375Mu from Uscn Life Science Inc.

Category ELISA Kit
Sensitivity The minimum detectable dose of this kit is typically less than 0.118ng/mL.
Range 0.313-20ng/mL The standard curve concentrations used for the ELISA’s were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

Human PHF8 ELISA Kit - E028844 from Biobool

Category ELISA Kit

Histone Lysine Demethylase PHF8 (PHF8), ELISA Kit - MBS9345578 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Histone Lysine Demethylase PHF8 (PHF8), ELISA Kit - MBS9350368 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Histone Lysine Demethylase PHF8 (PHF8), ELISA Kit - MBS9346655 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Histone Lysine Demethylase PHF8 (PHF8), ELISA Kit - MBS9355563 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Histone Lysine Demethylase PHF8 (PHF8), ELISA Kit - MBS9360341 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Histone Lysine Demethylase PHF8 (PHF8), ELISA Kit - MBS9348814 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Histone Lysine Demethylase PHF8 (PHF8), ELISA Kit - MBS9353231 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Histone Lysine Demethylase PHF8 (PHF8), ELISA Kit - MBS9363698 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Histone Lysine Demethylase PHF8 (PHF8), ELISA Kit - MBS9366678 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Histone Lysine Demethylase PHF8 (PHF8), ELISA Kit - MBS9354473 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Histone Lysine Demethylase PHF8 (PHF8), ELISA Kit - MBS9358333 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Histone Lysine Demethylase PHF8 (PHF8), ELISA Kit - MBS9350244 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Histone Lysine Demethylase PHF8 (PHF8), ELISA Kit - MBS9353018 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Histone Lysine Demethylase PHF8 (PHF8), ELISA Kit - MBS9352112 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Histone Lysine Demethylase PHF8 (PHF8), ELISA Kit - MBS9350748 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Histone Lysine Demethylase PHF8 (PHF8), ELISA Kit - MBS9349517 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Histone Lysine Demethylase PHF8 (PHF8), ELISA Kit - MBS9376864 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

PHD Finger Protein 8 (PHF8), ELISA Kit - MBS9371907 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Histone Lysine Demethylase PHF8 (PHF8), ELISA Kit - MBS9351577 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Histone Lysine Demethylase PHF8 (PHF8), ELISA Kit - MBS9358572 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
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