GCKR

Gene Symbol	GCKR
Entrez Gene	2646
Alt Symbol	FGQTL5, GKRP
Species	Human
Gene Type	protein-coding
Description	glucokinase (hexokinase 4) regulator
Other Description	glucokinase regulatory protein
Swissprots	Q99522 Q53RY6 Q14397 B4DPQ2 A1L4C2
Accessions	AAP72013 AAY14850 CAA70779 CAB61828 EAX00568 Q14397 AK291846 BAF84535 AK298448 BAG60664 AK303784 BAG64742 AK309599 BC130481 AAI30482 BC130483 AAI30484 CD368544 DA011063 HQ258318 ADR83072 Z48475 CAA88367 XM_011532761 XP_011531063 XM_011532762 XP_011531064 XM_011532763 XP_011531065 NM_001486 NP_001477
Function	Inhibits glucokinase (GCK) by forming an inactive complex with this enzyme. The affinity of GCKR for GCK is modulated by fructose metabolites: GCKR with bound fructose 6- phosphate has increased affinity for GCK, while GCKR with bound fructose 1-phosphate has strongly decreased affinity for GCK and does not inhibit GCK activity. {ECO:0000269|PubMed:23621087, ECO:0000269|PubMed:23733961}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:10456334}. Nucleus {ECO:0000269|PubMed:10456334}. Note=Under low glucose concentrations, GKRP associates with GCK and the inactive complex is recruited to the hepatocyte nucleus.
Tissue Specificity	Found in liver and pancreas. Not detected in muscle, brain, heart, thymus, intestine, uterus, adipose tissue, kidney, adrenal, lung or spleen. {ECO:0000269|PubMed:19643913, ECO:0000269|PubMed:9570959}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Mouse/Human/Rat GCKR ELISA Kit (Cell-Based ELISA) - LS-F3190 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate

Glucokinase Regulatory Protein, GKRP, Human, ELISA Kit - E-EL-H1819 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Glucokinase regulatory protein, GCKR, Human, ELISA Kit - E1365h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t

Glucokinase Regulatory Protein, GKRP, Rabbit, ELISA Kit - E-EL-RB0752 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Glucokinase Regulatory Protein, GKRP, Chicken, ELISA Kit - E-EL-Ch0263 from ARP American Research Products Category ELISA Kit Prices $445.50 Sizes 96 t

Glucokinase Regulatory Protein, GKRP, Porcine, ELISA Kit - E-EL-P0230 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Glucokinase Regulatory Protein, GKRP, Sheep, ELISA Kit - E-EL-S0468 from ARP American Research Products Category ELISA Kit Prices $648.00 Sizes 96 t

Glucokinase Regulatory Protein, GKRP, Guinea Pig, ELISA Kit - E-EL-GP0036 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Glucokinase Regulatory Protein, GKRP, Monkey, ELISA Kit - E-EL-MK1499 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Human GKRP ELISA Kit - HG0195 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Anserine GKRP ELISA Kit - AG0195 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Glucokinase Regulatory Protein, ELISA Kit - MBS755601 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Glucokinase Regulatory Protein, ELISA Kit - MBS021650 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1ng/ml. Range 0.625ng/ml-20ng/ml.

Glucokinase Regulatory Protein, ELISA Kit - MBS014228 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Glucokinase Regulatory Protein, ELISA Kit - MBS750235 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 1.0 ng/mL.

Glucokinase Regulatory Protein, ELISA Kit - MBS748983 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Glucokinase Regulatory Protein, ELISA Kit - MBS725699 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Glucokinase Regulatory Protein, ELISA Kit - MBS009412 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Glucokinase Regulatory Protein, ELISA Kit - MBS024261 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Glucokinase Regulatory Protein, ELISA Kit - MBS753613 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Glucokinase Regulatory Protein, ELISA Kit - MBS728783 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Glucokinase Regulatory Protein, ELISA Kit - MBS005092 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Glucokinase Regulatory Protein, ELISA Kit - MBS016612 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Glucokinase Regulatory Protein, ELISA Kit - MBS720106 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 1.0 ng/mL.

Glucokinase Regulatory Protein, ELISA Kit - MBS015855 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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