| Gene Symbol | PRAF2 |
|---|---|
| Entrez Gene | 11230 |
| Alt Symbol | JM4 |
| Species | Human |
| Gene Type | protein-coding |
| Description | PRA1 domain family, member 2 |
| Other Description | Jena-Muenchen 4|PRA1 family protein 2 |
| Swissprots | O60831 B2RD20 |
| Accessions | EAW50706 EAW50707 O60831 AA720948 AJ005896 CAA06753 AK023433 BAG51191 AK310550 AK315374 BAG37767 BC021213 AAH21213 CB155577 CR457023 CAG33304 NM_007213 NP_009144 |
| Function | May be involved in ER/Golgi transport and vesicular traffic. Plays a proapoptic role in cerulenin-induced neuroblastoma apoptosis. {ECO:0000269|PubMed:17975142, ECO:0000269|PubMed:18395978}. |
| Subcellular Location | Endosome membrane {ECO:0000305|PubMed:17975142}; Multi-pass membrane protein {ECO:0000305|PubMed:17975142}. |
| Tissue Specificity | Strong expression in the brain, small intestine, lung, spleen, and pancreas as well as in tumor tissues of the breast, colon, lung and ovary, with a weaker expression in normal tissues of the same patient. High expression in neuroblastic tumors. Strongly expressed in Purkinje cells and more moderately in cells of the molecular and the granular layers in the cerebellum. Detected in neuronal cells, but not in non- neuronal cells in the cerebral cortex, hippocampus, and lateral ventricles. {ECO:0000269|PubMed:16481131, ECO:0000269|PubMed:17975142, ECO:0000269|PubMed:18395978}. |
Mouse/Human/Rat PRAF2 ELISA Kit (Cell-Based ELISA) - LS-F2096 from LifeSpan Bioscience
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JM4 Colorimetric Cell-Based ELISA Kit - CB5388 from Assay Biotechnology
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PRA1 family protein 2, ELISA Kit - MBS280880 from MyBioSource
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JM4 ELISA Kit - DEIA-XYA1078 from Creative Diagnostics
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Human PRAF2 ELISA Kit - E030411 from Biobool
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JM4 Colorimetric Cell-Based ELISA Kit - EKA50331 from Biomatik
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