PRAF2

Gene Symbol	PRAF2
Entrez Gene	11230
Alt Symbol	JM4
Species	Human
Gene Type	protein-coding
Description	PRA1 domain family, member 2
Other Description	Jena-Muenchen 4|PRA1 family protein 2
Swissprots	O60831 B2RD20
Accessions	EAW50706 EAW50707 O60831 AA720948 AJ005896 CAA06753 AK023433 BAG51191 AK310550 AK315374 BAG37767 BC021213 AAH21213 CB155577 CR457023 CAG33304 NM_007213 NP_009144
Function	May be involved in ER/Golgi transport and vesicular traffic. Plays a proapoptic role in cerulenin-induced neuroblastoma apoptosis. {ECO:0000269|PubMed:17975142, ECO:0000269|PubMed:18395978}.
Subcellular Location	Endosome membrane {ECO:0000305|PubMed:17975142}; Multi-pass membrane protein {ECO:0000305|PubMed:17975142}.
Tissue Specificity	Strong expression in the brain, small intestine, lung, spleen, and pancreas as well as in tumor tissues of the breast, colon, lung and ovary, with a weaker expression in normal tissues of the same patient. High expression in neuroblastic tumors. Strongly expressed in Purkinje cells and more moderately in cells of the molecular and the granular layers in the cerebellum. Detected in neuronal cells, but not in non- neuronal cells in the cerebral cortex, hippocampus, and lateral ventricles. {ECO:0000269|PubMed:16481131, ECO:0000269|PubMed:17975142, ECO:0000269|PubMed:18395978}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human JM4 full length protein - ab161360 from Abcam Category Protein Source Wheat germ Species Human

Recombinant Human JM4 Protein - H00011230-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

PRAF2 Blocking Peptide - abx063736 from Abbexa Category Peptide Species Human, Mouse, Rat, Bovine, Monkey, Pig

JM4 / PRAF2 - H00011230-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

JM4 / PRAF2 - H00011230-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

PRAF2 Blocking Peptide - CBP2542 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Bovine, Monkey, Pig

PRAF2 (L166) Peptide - BS1195P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

JM4 / PRAF2 - TP302910 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

PRA1 family protein 2 (PRAF2), Recombinant Protein - MBS1124027 from MyBioSource Category Protein Prices $1,375.00, $1,835.00 Sizes 1 mg (E-Coli), 1 mg (Yeast) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

JM4 Recombinant Protein Antigen - NBP1-87886PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

PRAF2 Peptide, Human - M34GP12312H from Creative Peptides Category Peptide Source Synthetic. Species Human

PRA1 family protein 2 (PRAF2), Recombinant Protein - MBS7026946 from MyBioSource Category Protein Prices $995.00, $1,985.00, $3,195.00 Sizes 10 µg, 50 µg, 100 µg Source Cell Free Expression Species Human

PRAF2 peptide - orb218405 from Biorbyt Category Peptide Species Human, Mouse, Rat, Monkey

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