| Gene Symbol | PRAF2 |
|---|---|
| Entrez Gene | 11230 |
| Alt Symbol | JM4 |
| Species | Human |
| Gene Type | protein-coding |
| Description | PRA1 domain family, member 2 |
| Other Description | Jena-Muenchen 4|PRA1 family protein 2 |
| Swissprots | O60831 B2RD20 |
| Accessions | EAW50706 EAW50707 O60831 AA720948 AJ005896 CAA06753 AK023433 BAG51191 AK310550 AK315374 BAG37767 BC021213 AAH21213 CB155577 CR457023 CAG33304 NM_007213 NP_009144 |
| Function | May be involved in ER/Golgi transport and vesicular traffic. Plays a proapoptic role in cerulenin-induced neuroblastoma apoptosis. {ECO:0000269|PubMed:17975142, ECO:0000269|PubMed:18395978}. |
| Subcellular Location | Endosome membrane {ECO:0000305|PubMed:17975142}; Multi-pass membrane protein {ECO:0000305|PubMed:17975142}. |
| Tissue Specificity | Strong expression in the brain, small intestine, lung, spleen, and pancreas as well as in tumor tissues of the breast, colon, lung and ovary, with a weaker expression in normal tissues of the same patient. High expression in neuroblastic tumors. Strongly expressed in Purkinje cells and more moderately in cells of the molecular and the granular layers in the cerebellum. Detected in neuronal cells, but not in non- neuronal cells in the cerebral cortex, hippocampus, and lateral ventricles. {ECO:0000269|PubMed:16481131, ECO:0000269|PubMed:17975142, ECO:0000269|PubMed:18395978}. |
Human PRAF2 cDNA clone(NM_007213.1) - CDFH015000 from Creative Biomart
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Human PRAF2 ORF Clone(NM_007213.1) - CDCR294599 from Creative Biomart
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Human PRAF2 ORF Clone(NM_007213.1) - CDCR294600 from Creative Biomart
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Human PRAF2 ORF Clone(NM_007213.1) - CDCR294601 from Creative Biomart
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human PRAF2 ORF clone (NM_007213.1) - CDCH067260 from Creative biogene
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Human PRAF2 cDNA Clone(NM_007213.1) - CDFH015000 from Creative biogene
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