ANG

Gene Symbol ANG
Entrez Gene 283
Alt Symbol ALS9, HEL168, RAA1, RNASE4, RNASE5
Species Human
Gene Type protein-coding
Description angiogenin, ribonuclease, RNase A family, 5
Other Description RNase 5|angiogenin|epididymis luminal protein 168|ribonuclease 5|ribonuclease A A1
Swissprots P03950 Q8WXE7 Q53X86 Q05CV1 Q6P5T2
Accessions AAA51678 AAL67710 AAL67711 AAL67712 AAL67713 AAL67714 CDG31911 EAW66450 EAW66451 P03950 AK313989 BAG36701 AV646929 BC020704 AAH20704 BC054880 AAH54880 BC062698 AAH62698 BQ773604 CB157060 CB963791 CR407633 CAG28561 FJ236304 ACI45236 HQ447651 ADQ32136 NM_001097577 NP_001091046 NM_001145 NP_001136
Function Binds to actin on the surface of endothelial cells; once bound, angiogenin is endocytosed and translocated to the nucleus. Stimulates ribosomal RNA synthesis including that containing the initiation site sequences of 45S rRNA. Cleaves tRNA within anticodon loops to produce tRNA-derived stress-induced fragments (tiRNAs) which inhibit protein synthesis and triggers the assembly of stress granules (SGs). Angiogenin induces vascularization of normal and malignant tissues. Angiogenic activity is regulated by interaction with RNH1 in vivo. {ECO:0000269|PubMed:12051708, ECO:0000269|PubMed:1400510, ECO:0000269|PubMed:19354288, ECO:0000269|PubMed:21855800}.
Subcellular Location Secreted, extracellular space, extracellular matrix, basement membrane. Nucleus, nucleolus. Note=Rapidly endocytosed by target cells and translocated to the nucleus where it accumulates in the nucleolus and binds to DNA.
Tissue Specificity Expressed predominantly in the liver. Also detected in endothelial cells and spinal cord neurons. {ECO:0000269|PubMed:17886298, ECO:0000269|PubMed:2440105}.

Angiogenin (ANG) Human ELISA Kit - ab99970 from Abcam

Category ELISA Kit
Prices $489.00
Sizes 1 x 96 tests
Sensitivity < 1.5 pg/ml
Range 1.64 pg/ml - 400 pg/ml
Representative standard curve using ab99970.

Human Angiogenin / ANG ELISA Kit (Sandwich ELISA) - LS-F2401 from LifeSpan Bioscience

Category ELISA Kit
Prices $570.00
Sizes 1 plate
Sensitivity 12 pg/ml
Range 1.638-160 pg/ml

Human Angiogenin / ANG ELISA Kit (Sandwich ELISA) - LS-F3957 from LifeSpan Bioscience

Category ELISA Kit
Prices $470.00
Sizes 1 plate
Sensitivity 13.5 pg/ml
Range 1.638-160 pg/ml

Bovine Angiogenin / ANG ELISA Kit (Sandwich ELISA) - LS-F6114 from LifeSpan Bioscience

Category ELISA Kit
Prices $780.00
Sizes 1 plate
Sensitivity 6.4 pg/ml
Range 1.638-160 pg/ml

Pig Angiogenin / ANG ELISA Kit (Sandwich ELISA) - LS-F6055 from LifeSpan Bioscience

Category ELISA Kit
Prices $780.00
Sizes 1 plate
Sensitivity 0.257 ng/ml
Range 1.638-160 pg/ml

Mouse Angiogenin / ANG ELISA Kit (Sandwich ELISA) - LS-F5440 from LifeSpan Bioscience

Category ELISA Kit
Prices $670.00
Sizes 1 plate
Sensitivity 0.128 ng/ml
Range 1.638-160 pg/ml

Human Angiogenin / ANG ELISA Kit (Sandwich ELISA) - LS-F30 from LifeSpan Bioscience

Category ELISA Kit
Prices $460.00, $840.00, $1,960.00
Sizes 1 plate, 2 plate, 5 plate
Sensitivity 1.638 pg/ml
Range 1.638-160 pg/ml

Human Angiogenin / ANG ELISA Kit (Sandwich ELISA) - LS-F674 from LifeSpan Bioscience

Category ELISA Kit
Prices $450.00
Sizes 1 plate
Range 1.638-160 pg/ml

Human Angiogenin / ANG ELISA Kit (Sandwich ELISA) - LS-F9975 from LifeSpan Bioscience

Category ELISA Kit
Prices $530.00
Sizes 1 plate
Sensitivity 69.915 pg/ml
Range 1.638-160 pg/ml

Human Angiogenin / ANG ELISA Kit (Sandwich ELISA) - LS-F10820 from LifeSpan Bioscience

Category ELISA Kit
Prices $530.00
Sizes 1 plate
Sensitivity 15.6
Range 1.638-160 pg/ml

Mouse Angiogenin / ANG ELISA Kit (Sandwich ELISA) - LS-F10821 from LifeSpan Bioscience

Category ELISA Kit
Prices $530.00
Sizes 1 plate
Sensitivity 15.6 pg/ml
Range 1.638-160 pg/ml

Human Angiogenin ELISA Kit - RAB0014 from Sigma-Aldrich

Category ELISA Kit
Prices $438.50
Sizes 1 kt
<B>Standard Curve</B><BR/>: Typical Standard Curve for Human ANGIOGENIN ELISA Kit, <B>Cat. No. RAB0014</B>. The standard curve(s) displayed are for demonstration only. A standard curve must be run with each assay.

Human Angiogenin Quantikine ELISA Kit - DAN00 from R&D Systems

Category ELISA Kit
Prices $479.00
Sizes 1 kit
Sensitivity 6 pg/mL
Range 78.1 - 5,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma)
Human Angiogenin Quantikine ELISA Kit

Human Angiogenin DuoSet ELISA - DY265 from R&D Systems

Category ELISA Kit
Prices $649.00
Sizes 1 kit (for 15 Plates)
Range 7.81 - 500 pg/mL

Human ANG ELISA Kit - 55R-1555 from Fitzgerald

Category ELISA Kit
Prices $460.00
Sizes 1 kit

Human Angiogenin ELISA kit - 55R-2081 from Fitzgerald

Category ELISA Kit
Prices $505.00
Sizes 96 tests

Human Angiostatin ELISA kit - 55R-2082 from Fitzgerald

Category ELISA Kit
Prices $505.00
Sizes 96 tests

Angiogenin ELISA Kit (Human) : 96 Wells (OKAG00193) - OKAG00193 from Aviva Systems Biology

Category ELISA Kit
Prices $390.00
Sizes 96 wells
Sensitivity 16 pg/mL
Range 16-500 pg/mL

Human ANG ELISA Kit - abx056008 from Abbexa

Category ELISA Kit

Human ANG ELISA kit - abx050007 from Abbexa

Category ELISA Kit
Sensitivity < 12pg/ml
Range 78 pg/ml-5000 pg/ml

Human Angiogenin ELISA Kit - abx150645 from Abbexa

Category ELISA Kit
Sensitivity 14.4 pg/ml
Range 31.25 pg/ml - 2000 pg/ml

Angiogenin, ANG, Human, ELISA Kit - E-EL-H0006 from ARP American Research Products

Category ELISA Kit
Prices $522.00
Sizes 96 t
Sensitivity 9.375
Range 15.625-1000pg/mL

Angiostatin, ANG, Human, ELISA Kit - E-EL-H0324 from ARP American Research Products

Category ELISA Kit
Prices $522.00
Sizes 96 t
Sensitivity 18.75
Range 31.25-2000ng/mL
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