Gene Symbol | TFAP2B |
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Entrez Gene | 7021 |
Alt Symbol | AP-2B, AP2-B |
Species | Human |
Gene Type | protein-coding |
Description | transcription factor AP-2 beta (activating enhancer binding protein 2 beta) |
Other Description | AP2-beta|activating enhancer binding protein 2 beta|activating enhancer-binding protein 2-beta|transcription factor AP-2-beta |
Swissprots | Q9Y3K3 Q9NU99 Q92481 Q9Y214 Q9NQ63 Q9UJI7 Q5JYX6 |
Accessions | CAA71047 CAC01130 EAX04355 EAX04356 EAX04357 Q92481 AK291172 BAF83861 AK313749 BAG36489 AU141084 BC037225 AAH37225 BU738725 DQ891443 ABM82369 DQ894621 ABM85547 X95694 CAA64990 XM_006715176 XP_006715239 XM_006715177 XP_006715240 XM_011514834 XP_011513136 XM_011514835 XP_011513137 XM_011514836 XP_011513138 XM_011514837 XP_011513139 NM_003221 NP_003212 |
Function | Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-beta appears to be required for normal face and limb development and for proper terminal differentiation and function of renal tubular epithelia. {ECO:0000269|PubMed:11694877}. |
Subcellular Location | Nucleus {ECO:0000305}. |
AP-2β Antibody - 2509 from Cell Signaling Technology
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AP-2β (A-1) - sc-166441 from Santa Cruz Biotechnology
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AP-2β (C-20) - sc-6310 from Santa Cruz Biotechnology
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AP-2β (D-20) - sc-31932 from Santa Cruz Biotechnology
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AP-2β (H-20) - sc-31933 from Santa Cruz Biotechnology
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AP-2β (H-87) - sc-8976 from Santa Cruz Biotechnology
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AP-2β (1G6/2) - sc-53161 from Santa Cruz Biotechnology
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AP-2β (1F3/8) - sc-53160 from Santa Cruz Biotechnology
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Anti-AP2 beta antibody [AP2b 1F3/8] - ab18113 from Abcam
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Anti-AP2 beta antibody [AP2b 1G6/2] - ab18114 from Abcam
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Anti-AP2 beta antibody [EPR15255] - ab186424 from Abcam
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Anti-TFAP2B / AP2 Beta Antibody (N-Terminus) IHC-plus⢠- LS-B10848 from LifeSpan Bioscience
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Anti-TFAP2B / AP2 Beta Antibody - LS-C34991 from LifeSpan Bioscience
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Anti-TFAP2B / AP2 Beta Antibody - LS-C90693 from LifeSpan Bioscience
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Anti-TFAP2B / AP2 Beta Antibody (aa12-460) - LS-C126392 from LifeSpan Bioscience
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Anti-TFAP2B / AP2 Beta Antibody (aa372-421) - LS-C31068 from LifeSpan Bioscience
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Anti-TFAP2B / AP2 Beta Antibody (aa121-218) - LS-C126393 from LifeSpan Bioscience
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Anti-TFAP2B / AP2 Beta Antibody (N-Terminus) - LS-C81999 from LifeSpan Bioscience
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Anti-TFAP2B / AP2 Beta Antibody (aa480-510, AP) - LS-C217928 from LifeSpan Bioscience
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Anti-TFAP2B / AP2 Beta Antibody (aa35-84) - LS-C109792 from LifeSpan Bioscience
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Anti-TFAP2B / AP2 Beta Antibody (aa480-510, Biotin) - LS-C217930 from LifeSpan Bioscience
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Anti-TFAP2B / AP2 Beta Antibody (aa480-510, APC) - LS-C217929 from LifeSpan Bioscience
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Anti-TFAP2B / AP2 Beta Antibody (aa480-510, Azide-free, HRP) - LS-C217931 from LifeSpan Bioscience
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Anti-TFAP2B / AP2 Beta Antibody (aa480-510, FITC) - LS-C217932 from LifeSpan Bioscience
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Anti-TFAP2B / AP2 Beta Antibody (aa480-510, PE) - LS-C217933 from LifeSpan Bioscience
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