Gene Symbol | TFAP2B |
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Entrez Gene | 7021 |
Alt Symbol | AP-2B, AP2-B |
Species | Human |
Gene Type | protein-coding |
Description | transcription factor AP-2 beta (activating enhancer binding protein 2 beta) |
Other Description | AP2-beta|activating enhancer binding protein 2 beta|activating enhancer-binding protein 2-beta|transcription factor AP-2-beta |
Swissprots | Q9Y3K3 Q9NU99 Q92481 Q9Y214 Q9NQ63 Q9UJI7 Q5JYX6 |
Accessions | CAA71047 CAC01130 EAX04355 EAX04356 EAX04357 Q92481 AK291172 BAF83861 AK313749 BAG36489 AU141084 BC037225 AAH37225 BU738725 DQ891443 ABM82369 DQ894621 ABM85547 X95694 CAA64990 XM_006715176 XP_006715239 XM_006715177 XP_006715240 XM_011514834 XP_011513136 XM_011514835 XP_011513137 XM_011514836 XP_011513138 XM_011514837 XP_011513139 NM_003221 NP_003212 |
Function | Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-beta appears to be required for normal face and limb development and for proper terminal differentiation and function of renal tubular epithelia. {ECO:0000269|PubMed:11694877}. |
Subcellular Location | Nucleus {ECO:0000305}. |
TFAP2B cDNA (ANA10539) - ANA10539 from Aviva Systems Biology
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TFAP2B cDNA (ANA10540) - ANA10540 from Aviva Systems Biology
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Human TFAP2B cDNA clone(NM_003221.3) - CDFH019478 from Creative Biomart
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Human TFAP2B cDNA clone(NM_003221.3) - CDFH019479 from Creative Biomart
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human TFAP2B ORF clone - CDCH090406 from Creative Biomart
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human TFAP2B ORF clone - CDCH090407 from Creative Biomart
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human TFAP2B ORF clone - CDCH090408 from Creative Biomart
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human TFAP2B ORF clone - CDCH090409 from Creative Biomart
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Human TFAP2B ORF clone(NM_003221.3) - CDCG000055 from Creative Biomart
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Human TFAP2B ORF Clone(NM_003221.3) - CDCL178274 from Creative Biomart
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Human TFAP2B ORF Clone(NM_003221.3) - CDCR284995 from Creative Biomart
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Human TFAP2B ORF Clone(NM_003221.3) - CDCR284996 from Creative Biomart
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human TFAP2B ORF clone (NM_003221.3) - CDCH090408 from Creative biogene
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Human TFAP2B cDNA Clone(NM_003221.3) - CDFH019478 from Creative biogene
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Human TFAP2B cDNA Clone(NM_003221.3) - CDFH019479 from Creative biogene
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