Gene Symbol | TFAP2B |
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Entrez Gene | 7021 |
Alt Symbol | AP-2B, AP2-B |
Species | Human |
Gene Type | protein-coding |
Description | transcription factor AP-2 beta (activating enhancer binding protein 2 beta) |
Other Description | AP2-beta|activating enhancer binding protein 2 beta|activating enhancer-binding protein 2-beta|transcription factor AP-2-beta |
Swissprots | Q9Y3K3 Q9NU99 Q92481 Q9Y214 Q9NQ63 Q9UJI7 Q5JYX6 |
Accessions | CAA71047 CAC01130 EAX04355 EAX04356 EAX04357 Q92481 AK291172 BAF83861 AK313749 BAG36489 AU141084 BC037225 AAH37225 BU738725 DQ891443 ABM82369 DQ894621 ABM85547 X95694 CAA64990 XM_006715176 XP_006715239 XM_006715177 XP_006715240 XM_011514834 XP_011513136 XM_011514835 XP_011513137 XM_011514836 XP_011513138 XM_011514837 XP_011513139 NM_003221 NP_003212 |
Function | Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-beta appears to be required for normal face and limb development and for proper terminal differentiation and function of renal tubular epithelia. {ECO:0000269|PubMed:11694877}. |
Subcellular Location | Nucleus {ECO:0000305}. |
Human AP2 beta full length protein - ab159674 from Abcam
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Human AP2 beta protein fragment - ab159675 from Abcam
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TFAP2B / AP2 Beta Antibody Blocking Peptide - LS-E2312 from LifeSpan Bioscience
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TFAP2B / AP2 Beta Antibody Blocking Peptide - LS-E22433 from LifeSpan Bioscience
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TFAP2B / AP2 Beta Antibody Blocking Peptide - LS-E11811 from LifeSpan Bioscience
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TFAP2B / AP2 Beta Antibody Blocking Peptide - LS-E13753 from LifeSpan Bioscience
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TFAP2B / AP2 Beta Antibody Blocking Peptide - LS-E13752 from LifeSpan Bioscience
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AP-2 beta/TFAP2B Partial Recombinant Protein - H00007021-Q01 from Novus Biologicals
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Recombinant Human AP-2 beta/TFAP2B Protein - H00007021-P01 from Novus Biologicals
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TFAP2B-Antibody-C-term-Blocking-peptide - BP13256b from Abgent, a WuXi AppTec company
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TFAP2B Protein Lysate (APL10539) - APL10539 from Aviva Systems Biology
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TFAP2B Protein Lysate (APL10540) - APL10540 from Aviva Systems Biology
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AP-2 beta / TFAP2B - H00007021-P01-10 from Acris Antibodies
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AP-2 beta / TFAP2B - H00007021-P01-25 from Acris Antibodies
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AP-2 beta / TFAP2B - H00007021-Q01-10 from Acris Antibodies
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AP-2 beta / TFAP2B - H00007021-Q01-25 from Acris Antibodies
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TFAP2B fusion protein - Ag3853 from Proteintech Group
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Recombinant Human TFAP2B, GST-tagged - TFAP2B-3193H from Creative Biomart
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Recombinant Human Transcription factor AP-2-beta(TFAP2B) - CSB-YP852874HU CSB-EP852874HU CSB-BP852874HU CSB-MP852874HU from Cusabio
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TFAP2B Peptide - abx164847 from Abbexa
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AP-2 beta / TFAP2B (full length, N-term HIS tag) - TP760475 from Acris Antibodies
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AP-2 beta/TFAP2B Protein - NBP1-89063PEP from Novus Biologicals
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TFAP2B Protein Lysate - orb333442 from Biorbyt
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TFAP2B Protein Lysate - orb333441 from Biorbyt
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TFAP2B Peptide, Human - M34GP15833H from Creative Peptides
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