Gene Symbol | TFAP2B |
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Entrez Gene | 7021 |
Alt Symbol | AP-2B, AP2-B |
Species | Human |
Gene Type | protein-coding |
Description | transcription factor AP-2 beta (activating enhancer binding protein 2 beta) |
Other Description | AP2-beta|activating enhancer binding protein 2 beta|activating enhancer-binding protein 2-beta|transcription factor AP-2-beta |
Swissprots | Q9Y3K3 Q9NU99 Q92481 Q9Y214 Q9NQ63 Q9UJI7 Q5JYX6 |
Accessions | CAA71047 CAC01130 EAX04355 EAX04356 EAX04357 Q92481 AK291172 BAF83861 AK313749 BAG36489 AU141084 BC037225 AAH37225 BU738725 DQ891443 ABM82369 DQ894621 ABM85547 X95694 CAA64990 XM_006715176 XP_006715239 XM_006715177 XP_006715240 XM_011514834 XP_011513136 XM_011514835 XP_011513137 XM_011514836 XP_011513138 XM_011514837 XP_011513139 NM_003221 NP_003212 |
Function | Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-beta appears to be required for normal face and limb development and for proper terminal differentiation and function of renal tubular epithelia. {ECO:0000269|PubMed:11694877}. |
Subcellular Location | Nucleus {ECO:0000305}. |
Transcription factor AP-2-beta, TFAP2B, Human, ELISA Kit - E0510h from ARP American Research Products
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transcription factor AP-2 beta (activating enhancer binding protein 2 beta) , ELISA Kit - MBS9330202 from MyBioSource
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Mouse TFAP2B / AP2 Beta ELISA Kit (Custom ELISA) - LS-F14679 from LifeSpan Bioscience
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Human TFAP2B / AP2 Beta ELISA Kit (Custom ELISA) - LS-F14680 from LifeSpan Bioscience
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Dog TFAP2B / AP2 Beta ELISA Kit (Custom ELISA) - LS-F14681 from LifeSpan Bioscience
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Human Transcription factor AP-2-beta ELISA Kit - abx253889 from Abbexa
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Human Transcription factor AP-2-beta ELISA Kit - EKE53612 from Biomatik
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TFAP2B - EKH1866 from Nordic BioSite
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Human TFAP2B ELISA Kit - E038795 from Biobool
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TFAP2B ELISA Kit (Human) (OKEH04335) - OKEH04335 from Aviva Systems Biology
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Transcription factor AP-2-beta, ELISA Kit - MBS765461 from MyBioSource
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Transcription factor AP-2-beta, ELISA Kit - MBS2881569 from MyBioSource
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Human TFAP2B / AP2 Beta ELISA Kit (Sandwich ELISA) - LS-F34043 from LifeSpan Bioscience
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