Gene Symbol | KRT18 |
---|---|
Entrez Gene | 3875 |
Alt Symbol | CYK18, K18 |
Species | Human |
Gene Type | protein-coding |
Description | keratin 18, type I |
Other Description | CK-18|cell proliferation-inducing gene 46 protein|cell proliferation-inducing protein 46|cytokeratin 18|cytokeratin-18|keratin, type I cytoskeletal 18|keratin-18 |
Swissprots | P05783 Q9BW26 Q53G38 Q5U0N8 |
Accessions | AAA59461 CBU30436 CBU83085 EAW96655 EAW96656 P05783 AK129587 AK223093 BAD96813 AK308506 AK313988 BAG36700 AY762101 AAX07828 BC000180 AAH00180 BC000698 AAH00698 BC004253 AAH04253 BC008636 AAH08636 BC009754 AAH09754 BC020982 AAH20982 BC072017 AAH72017 BG753529 BT019412 AAV38219 CD106591 DQ890555 ABM92172 DQ893715 ABM84641 L32537 AAA73889 X12876 CAA31369 X12881 CAA31375 X12883 CAA31377 NM_000224 NP_000215 NM_199187 NP_954657 |
Function | Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection. {ECO:0000250, ECO:0000269|PubMed:15529338, ECO:0000269|PubMed:16424149, ECO:0000269|PubMed:17213200, ECO:0000269|PubMed:7523419, ECO:0000269|PubMed:8522591, ECO:0000269|PubMed:9298992, ECO:0000269|PubMed:9524113}. |
Subcellular Location | Cytoplasm, perinuclear region. Nucleus, nucleolus. |
Tissue Specificity | Expressed in colon, placenta, liver and very weakly in exocervix. Increased expression observed in lymph nodes of breast carcinoma. {ECO:0000269|PubMed:17213200, ECO:0000269|PubMed:2422083, ECO:0000269|PubMed:2434380, ECO:0000269|PubMed:2434381}. |
Top Pathways | Pathogenic Escherichia coli infection |
Human KRT18 / CK18 / Cytokeratin 18 ELISA Kit (Sandwich ELISA) - LS-F4491 from LifeSpan Bioscience
|
||||||||||
Rat KRT18 / CK18 / Cytokeratin 18 ELISA Kit (Sandwich ELISA) - LS-F5977 from LifeSpan Bioscience
|
||||||||||
Human Phospho-KRT18 / CK18 / Cytokeratin 18 (Ser52) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1344 from LifeSpan Bioscience
|
||||||||||
Mouse/Human/Rat KRT18 / CK18 / Cytokeratin 18 ELISA Kit (Cell-Based ELISA) - LS-F2103 from LifeSpan Bioscience
|
||||||||||
Mouse/Human/Rat Phospho-KRT18 / CK18 / Cytokeratin 18 (Ser33) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1044 from LifeSpan Bioscience
|
||||||||||
Mouse KRT18 / CK18 / Cytokeratin 18 ELISA Kit (Sandwich ELISA) - LS-F8614 from LifeSpan Bioscience
|
||||||||||
Pig KRT18 / CK18 / Cytokeratin 18 ELISA Kit (Sandwich ELISA) - LS-F9458 from LifeSpan Bioscience
|
||||||||||
Mouse KRT18 / CK18 / Cytokeratin 18 ELISA Kit (Sandwich ELISA) - LS-F11862 from LifeSpan Bioscience
|
||||||||||
Human KRT18 / CK18 / Cytokeratin 18 ELISA Kit (Sandwich ELISA) - LS-F11861 from LifeSpan Bioscience
|
||||||||||
Human Cytokeratin 18 ELISA Kit - abx052193 from Abbexa
|
||||||||||
Cytokeratin 18, CK-18/KRT18, Human, ELISA Kit - E-EL-H2072 from ARP American Research Products
|
||||||||||
Cytokeratin 18, CK-18, Human, ELISA Kit - CSB-E09172h from ARP American Research Products
|
||||||||||
CytoKeratin 18, Human, ELISA Kit - E01C0761 from ARP American Research Products
|
||||||||||
Keratin 18 (KRT18), Human, ELISA Kit - SEB231Hu from ARP American Research Products
|
||||||||||
Keratin, type I cytoskeletal 18, KRT18, Human, ELISA Kit - E1231h from ARP American Research Products
|
||||||||||
Cytokeratin 18, CK-18/KRT18, Rabbit, ELISA Kit - E-EL-RB1570 from ARP American Research Products
|
||||||||||
Cytokeratin 18, CK-18/KRT18, Chicken, ELISA Kit - E-EL-Ch1315 from ARP American Research Products
|
||||||||||
Cytokeratin 18, CK-18/KRT18, Porcine, ELISA Kit - E-EL-P1298 from ARP American Research Products
|
||||||||||
Cytokeratin 18, CK-18/KRT18, Sheep, ELISA Kit - E-EL-S0825 from ARP American Research Products
|
||||||||||
Cytokeratin 18, CK-18/KRT18, Monkey, ELISA Kit - E-EL-MK0780 from ARP American Research Products
|
||||||||||
KRT18 (Human) IP-WB Antibody Pair - H00003875-PW1 from Acris Antibodies
|
||||||||||
Keratin 18 Colorimetric Cell-Based ELISA Kit - CB5397 from Assay Biotechnology
|
||||||||||
Keratin 18 (Phospho-Ser33) Colorimetric Cell-Based ELISA Kit - CBP1016 from Assay Biotechnology
|
||||||||||
Keratin 18 (Phospho-Ser52) Colorimetric Cell-Based ELISA Kit - CBP1354 from Assay Biotechnology
|
||||||||||
Human CK-18/KRT18(Cytokeratin 18) ELISA Kit - E-EL-H2072 from Elabscience
|