KRT18

Gene Symbol KRT18
Entrez Gene 3875
Alt Symbol CYK18, K18
Species Human
Gene Type protein-coding
Description keratin 18, type I
Other Description CK-18|cell proliferation-inducing gene 46 protein|cell proliferation-inducing protein 46|cytokeratin 18|cytokeratin-18|keratin, type I cytoskeletal 18|keratin-18
Swissprots P05783 Q9BW26 Q53G38 Q5U0N8
Accessions AAA59461 CBU30436 CBU83085 EAW96655 EAW96656 P05783 AK129587 AK223093 BAD96813 AK308506 AK313988 BAG36700 AY762101 AAX07828 BC000180 AAH00180 BC000698 AAH00698 BC004253 AAH04253 BC008636 AAH08636 BC009754 AAH09754 BC020982 AAH20982 BC072017 AAH72017 BG753529 BT019412 AAV38219 CD106591 DQ890555 ABM92172 DQ893715 ABM84641 L32537 AAA73889 X12876 CAA31369 X12881 CAA31375 X12883 CAA31377 NM_000224 NP_000215 NM_199187 NP_954657
Function Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection. {ECO:0000250, ECO:0000269|PubMed:15529338, ECO:0000269|PubMed:16424149, ECO:0000269|PubMed:17213200, ECO:0000269|PubMed:7523419, ECO:0000269|PubMed:8522591, ECO:0000269|PubMed:9298992, ECO:0000269|PubMed:9524113}.
Subcellular Location Cytoplasm, perinuclear region. Nucleus, nucleolus.
Tissue Specificity Expressed in colon, placenta, liver and very weakly in exocervix. Increased expression observed in lymph nodes of breast carcinoma. {ECO:0000269|PubMed:17213200, ECO:0000269|PubMed:2422083, ECO:0000269|PubMed:2434380, ECO:0000269|PubMed:2434381}.
Top Pathways Pathogenic Escherichia coli infection

KRT18-Over-expression-Lysate - LY10924a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag KRT18 (arrow) using his tag antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the KRT18 gene

KRT18 293T Cell Transient Overexpression Lysate(Denatured) - H00003875-T01 from Acris Antibodies

Category Cell Lysate
Prices $320.00
Sizes 100 µl

KRT18 293 Cell Lysate - 400172 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

KRT18 293 Cell Lysate - 403416 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

Cytokeratin 18 Overexpression Lysate (Native) - NBL1-12386 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: Cytokeratin 18 Overexpression Lysate (Adult Normal) [NBL1-12386] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Cytokeratin 18.

Cytokeratin 18 Overexpression Lysate (Native) - NBL1-12385 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: Cytokeratin 18 Overexpression Lysate (Adult Normal) [NBL1-12385] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Cytokeratin 18.

Cytokeratin 18 (h): 293 Lysate - sc-110494 from Santa Cruz Biotechnology

Category Cell Lysate
Prices $205.00
Sizes 100 µg/200 µl
Species Human

Cytokeratin 18 (h): 293T Lysate - sc-174503 from Santa Cruz Biotechnology

Category Cell Lysate
Prices $205.00
Sizes 100 µg/200 µl
Species Human

KRT18 Over-expression Lysate Product - GWB-D2E768 from Genway Biotech

Category Cell Lysate
Prices $346.00
Sizes 100 µg
Species Human

KRT18 Over-expression Lysate Product - GWB-AEACB7 from Genway Biotech

Category Cell Lysate
Prices $445.00
Sizes 100 µg
Species Human

Cytokeratin 18 Overexpression Lysate (Denatured) - H00003875-T01 from Novus Biologicals

Category Cell Lysate
Prices $279.00
Sizes 100 µl

Panoply™ Human KRT18 Knockdown Stable Cell Line - CSC-DC008364 from Creative biogene

Category Cell Line
Species Human
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