KRT18

Gene Symbol	KRT18
Entrez Gene	3875
Alt Symbol	CYK18, K18
Species	Human
Gene Type	protein-coding
Description	keratin 18, type I
Other Description	CK-18|cell proliferation-inducing gene 46 protein|cell proliferation-inducing protein 46|cytokeratin 18|cytokeratin-18|keratin, type I cytoskeletal 18|keratin-18
Swissprots	P05783 Q9BW26 Q53G38 Q5U0N8
Accessions	AAA59461 CBU30436 CBU83085 EAW96655 EAW96656 P05783 AK129587 AK223093 BAD96813 AK308506 AK313988 BAG36700 AY762101 AAX07828 BC000180 AAH00180 BC000698 AAH00698 BC004253 AAH04253 BC008636 AAH08636 BC009754 AAH09754 BC020982 AAH20982 BC072017 AAH72017 BG753529 BT019412 AAV38219 CD106591 DQ890555 ABM92172 DQ893715 ABM84641 L32537 AAA73889 X12876 CAA31369 X12881 CAA31375 X12883 CAA31377 NM_000224 NP_000215 NM_199187 NP_954657
Function	Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection. {ECO:0000250, ECO:0000269|PubMed:15529338, ECO:0000269|PubMed:16424149, ECO:0000269|PubMed:17213200, ECO:0000269|PubMed:7523419, ECO:0000269|PubMed:8522591, ECO:0000269|PubMed:9298992, ECO:0000269|PubMed:9524113}.
Subcellular Location	Cytoplasm, perinuclear region. Nucleus, nucleolus.
Tissue Specificity	Expressed in colon, placenta, liver and very weakly in exocervix. Increased expression observed in lymph nodes of breast carcinoma. {ECO:0000269|PubMed:17213200, ECO:0000269|PubMed:2422083, ECO:0000269|PubMed:2434380, ECO:0000269|PubMed:2434381}.
Top Pathways	Pathogenic Escherichia coli infection

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-KRT18-cDNA-Clone - DC00336 from Abgent, a WuXi AppTec company Prices $580.50 Sizes 10 µg Species Human Accession BC000180

KRT18 - MBS1265669 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC000180

KRT18 - MBS1269777 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC000698

Human KRT18 cDNA clone(NM_199187.1) - CDFG013073 from Creative Biomart Species Human Accession NM_199187.1

Human KRT18 cDNA clone(NM_000224.2) - CDFH010084 from Creative Biomart Species Human Accession NM_000224.2

Human KRT18 ORF clone(NM_000224.2) - CDCL185080 from Creative Biomart Species Human Accession NM_000224.2

Human KRT18 ORF Clone(NM_000224.2) - CDCR279226 from Creative Biomart Species Human Accession NM_000224.2

Human KRT18 ORF Clone(NM_000224.2) - CDCR279227 from Creative Biomart Species Human Accession NM_000224.2

Human KRT18 ORF Clone(NM_000224.2) - CDCR279228 from Creative Biomart Species Human Accession NM_000224.2

Human KRT18 ORF Clone(NM_199187.1) - CDCR326571 from Creative Biomart Species Human Accession NM_199187.1

Human KRT18 ORF Clone(NM_199187.1) - CDCR326572 from Creative Biomart Species Human Accession NM_199187.1

Human KRT18 ORF Clone(NM_199187.1) - CDCR326573 from Creative Biomart Species Human Accession NM_199187.1

Human KRT18/Cytokeratin18 Gene ORF cDNA clone in cloning vector - HG13197-G from Sino Biological Species Human

Human KRT18/Cytokeratin18 Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG13197-ANG from Sino Biological Species Human

Human KRT18/Cytokeratin18 Gene ORF cDNA clone expression plasmid, C-HA tag - HG13197-CY from Sino Biological Species Human

Human KRT18/Cytokeratin18 Gene ORF cDNA clone expression plasmid, N-HA tag - HG13197-NY from Sino Biological Species Human

Human KRT18/Cytokeratin18 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG13197-NF from Sino Biological Species Human

Human KRT18/Cytokeratin18 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG13197-ACG from Sino Biological Species Human

Human KRT18/Cytokeratin18 Gene ORF cDNA clone expression plasmid, N-His tag - HG13197-NH from Sino Biological Species Human

Human KRT18/Cytokeratin18 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG13197-NM from Sino Biological Species Human

Human KRT18/Cytokeratin18 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG13197-CF from Sino Biological Species Human

Human KRT18/Cytokeratin18 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG13197-CM from Sino Biological Species Human

Human KRT18/Cytokeratin18 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG13197-ACR from Sino Biological Species Human

Human KRT18/Cytokeratin18 Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG13197-ANR from Sino Biological Species Human

Human KRT18/Cytokeratin18 Gene ORF cDNA clone expression plasmid, C-His tag - HG13197-CH from Sino Biological Species Human

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