IZUMO1

Gene Symbol	IZUMO1
Entrez Gene	284359
Alt Symbol	IZUMO
Species	Human
Gene Type	protein-coding
Description	izumo sperm-egg fusion 1
Other Description	OBF|izumo sperm-egg fusion protein 1|oocyte binding/fusion factor|sperm-specific protein Izumo
Swissprots	Q6Q8P6 Q8IYV9 Q6Q8P7
Accessions	EAW52395 EAW52396 EAW52397 EAW52398 Q8IYV9 AB195682 BAD91012 AK301750 BAG63212 AY552609 AAS59145 AY552610 AAS59146 BC034769 AAH34769 BC050460 DQ893362 ABM84288 DQ894535 ABM85461 DQ896767 ABM87766 EU176807 ABW03608 XM_005258793 XP_005258850 XM_005258797 XP_005258854 XM_005258798 XP_005258855 XM_011526811 XP_011525113 XM_011526812 XP_011525114 XM_011526813 XP_011525115 XM_011526814 XP_011525116 XM_011526815 XP_011525117 XM_011526816 XP_011525118 XM_011526817 XP_011525119 XR_243923 XR_430196 XR_935799 NM_182575 NP_872381
Function	Essential sperm cell-surface protein required for fertilization by acting as a ligand for IZUMO1R/JUNO receptor on egg. The IZUMO1:IZUMO1R/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion. The ligand-receptor interaction probably does not act as a membrane 'fusogen'. {ECO:0000269|PubMed:15759005}.
Subcellular Location	Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Tissue Specificity	Sperm-specific (at protein level). Detectable on sperm surface only after the acrosome reaction. {ECO:0000269|PubMed:15759005}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-IZUMO1-cDNA-Clone - DC06796 from Abgent, a WuXi AppTec company Prices $472.50 Sizes 10 µg Species Human Accession BC034769

Human IZUMO1 (NP_872381) VersaClone cDNA - RDC1097 from R&D Systems Prices $199.00 Sizes 10 µg Species Human

IZUMO1 cDNA (ANA10891) - ANA10891 from Aviva Systems Biology Prices $189.00 Sizes 1 µg Accession BC034769

IZUMO1 - MBS1267852 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC034769

Human IZUMO1 ORF Clone(NM_182575.2) - CDCL167540 from Creative Biomart Species Human Accession NM_182575.2

Human IZUMO1 Gene ORF cDNA clone in cloning vector - HG13520-G from Sino Biological Species Human

Human IZUMO1 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG13520-NF from Sino Biological Species Human

Human IZUMO1 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG13520-NM from Sino Biological Species Human

Human IZUMO1 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG13520-CF from Sino Biological Species Human

Human IZUMO1 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG13520-ACG from Sino Biological Species Human

Human IZUMO1 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG13520-CM from Sino Biological Species Human

Human IZUMO1 Gene ORF cDNA clone expression plasmid, C-HA tag - HG13520-CY from Sino Biological Species Human

Human IZUMO1 Gene ORF cDNA clone expression plasmid, N-His tag - HG13520-NH from Sino Biological Species Human

Human IZUMO1 Gene ORF cDNA clone expression plasmid - HG13520-UT from Sino Biological Species Human

Human IZUMO1 Gene ORF cDNA clone expression plasmid, C-His tag - HG13520-CH from Sino Biological Species Human

Human IZUMO1 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG13520-ACR from Sino Biological Species Human

Human IZUMO1 Gene ORF cDNA clone expression plasmid, N-HA tag - HG13520-NY from Sino Biological Species Human

Human IZUMO1 ORF clone (NM_182575.2) - CDCL122265 from Creative biogene Species Human

Human IZUMO1 ORF Clone (BC034769) - CDCS417704 from Creative biogene Species Human Accession Q8IYV9

Human IZUMO1 ORF clone (BC034769) - CDCB159915 from Creative biogene Species Human

Human IZUMO1 Gene cDNA Clone - orb143913 from Biorbyt Prices $264.00 Sizes 10 μg Species Human

Search more