IZUMO1

Gene Symbol IZUMO1
Entrez Gene 284359
Alt Symbol IZUMO
Species Human
Gene Type protein-coding
Description izumo sperm-egg fusion 1
Other Description OBF|izumo sperm-egg fusion protein 1|oocyte binding/fusion factor|sperm-specific protein Izumo
Swissprots Q6Q8P6 Q8IYV9 Q6Q8P7
Accessions EAW52395 EAW52396 EAW52397 EAW52398 Q8IYV9 AB195682 BAD91012 AK301750 BAG63212 AY552609 AAS59145 AY552610 AAS59146 BC034769 AAH34769 BC050460 DQ893362 ABM84288 DQ894535 ABM85461 DQ896767 ABM87766 EU176807 ABW03608 XM_005258793 XP_005258850 XM_005258797 XP_005258854 XM_005258798 XP_005258855 XM_011526811 XP_011525113 XM_011526812 XP_011525114 XM_011526813 XP_011525115 XM_011526814 XP_011525116 XM_011526815 XP_011525117 XM_011526816 XP_011525118 XM_011526817 XP_011525119 XR_243923 XR_430196 XR_935799 NM_182575 NP_872381
Function Essential sperm cell-surface protein required for fertilization by acting as a ligand for IZUMO1R/JUNO receptor on egg. The IZUMO1:IZUMO1R/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion. The ligand-receptor interaction probably does not act as a membrane 'fusogen'. {ECO:0000269|PubMed:15759005}.
Subcellular Location Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Tissue Specificity Sperm-specific (at protein level). Detectable on sperm surface only after the acrosome reaction. {ECO:0000269|PubMed:15759005}.

IZUMO1 (W-17) - sc-79543 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
IZUMO1 (W-17): sc-79543. Western blot analysis of IZUMO1 expression in mouse testis tissue extract.

IZUMO1 (N-20) - sc-79540 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-IZUMO1 antibody - ab118188 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-IZUMO1 antibody (ab118188) at 1/500 dilution + Fetal heart lysate

Anti-IZUMO1 antibody - ab82887 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-IZUMO1 antibody (ab82887) at 1 µg/ml + Fetal heart lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-IZUMO1 / IZUMO Antibody (aa77-105, AP) - LS-C260587 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-IZUMO1 / IZUMO Antibody (aa77-105) - LS-C159947 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
IZUM1 Antibody western blot of CEM cell line lysates (35 ug/lane). The IZUM1 antibody detected the IZUM1 protein (arrow).

Anti-IZUMO1 / IZUMO Antibody (aa77-105, APC) - LS-C260588 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-IZUMO1 / IZUMO Antibody (aa77-105, Biotin) - LS-C260589 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-IZUMO1 / IZUMO Antibody (aa77-105, FITC) - LS-C260590 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-IZUMO1 / IZUMO Antibody (aa77-105, Azide-free, HRP) - LS-C260591 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-IZUMO1 / IZUMO Antibody (aa77-105, PE) - LS-C260592 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-IZUMO1 / IZUMO Antibody (aa51-211) - LS-C178942 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-IZUMO1 / IZUMO Antibody (aa76-105) - LS-C322312 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-IZUMO1 / IZUMO Antibody (C-Terminus) - LS-C82662 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Fetal heart lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-IZUMO1 / IZUMO Antibody (aa51-211) - LS-C178709 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

IZUMO1 Antibody - NBP1-83086 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: IZUMO1 Antibody [NBP1-83086] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Negative control (vector only transfected HEK293T lysate). Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).

IZUMO1 Antibody - NBP1-69692 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: IZUMO1 Antibody [NBP1-69692] - This Anti-IZUMO1 antibody was used in Western Blot of Fetal Heart tissue lysate at a concentration of 1ug/ml.

Anti-IZUMO1 antibody produced in rabbit - HPA038104 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-IZUMO1: <B>Cat. No. HPA038104</B>: Immunohistochemical staining of human testis shows strong cytoplasmic positivity in cells in seminiferus ducts.

Anti-IZUMO1 antibody produced in rabbit - SAB2101187 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-IZUMO1: <B>Cat. No.SAB2101187</B>: IZUMO1 in Fetal Heart tissue lysate with IZUMO1 antibody at 1.0 μg/mL.

ANTI-IZUM1 (N-TERMINAL) antibody produced in rabbit - SAB1305786 from Sigma-Aldrich

Prices $326.00
Sizes 40 tst
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-IZUM1 (N-term): <B>Cat. No. SAB1305786</B>: IZUM1 Antibody (N-term) western blot analysis in CEM cell line lysates (35 μg/lane).

IZUMO1 antibody - C-terminal region (ARP51341_P050) - ARP51341_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

IZUM1-Antibody-N-term - AP18187a from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
IZUM1 Antibody (N-term) (Cat. #AP18187a) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the IZUM1 antibody detected the IZUM1 protein (arrow).

IZUMO1 antibody, C-term - GTX45858 from GeneTex

Prices $319.00
Sizes 50 μg
Host Rabbit
Clonality Polyclonal

IZUM1 Antibody - N-terminal region (OAAB13685) - OAAB13685 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

IZUMO1 antibody - orb78088 from Biorbyt

Prices $425.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
Western blot analysis of fetal heart lysate using IZUMO1 antibody
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