IZUMO1

Gene Symbol	IZUMO1
Entrez Gene	284359
Alt Symbol	IZUMO
Species	Human
Gene Type	protein-coding
Description	izumo sperm-egg fusion 1
Other Description	OBF|izumo sperm-egg fusion protein 1|oocyte binding/fusion factor|sperm-specific protein Izumo
Swissprots	Q6Q8P6 Q8IYV9 Q6Q8P7
Accessions	EAW52395 EAW52396 EAW52397 EAW52398 Q8IYV9 AB195682 BAD91012 AK301750 BAG63212 AY552609 AAS59145 AY552610 AAS59146 BC034769 AAH34769 BC050460 DQ893362 ABM84288 DQ894535 ABM85461 DQ896767 ABM87766 EU176807 ABW03608 XM_005258793 XP_005258850 XM_005258797 XP_005258854 XM_005258798 XP_005258855 XM_011526811 XP_011525113 XM_011526812 XP_011525114 XM_011526813 XP_011525115 XM_011526814 XP_011525116 XM_011526815 XP_011525117 XM_011526816 XP_011525118 XM_011526817 XP_011525119 XR_243923 XR_430196 XR_935799 NM_182575 NP_872381
Function	Essential sperm cell-surface protein required for fertilization by acting as a ligand for IZUMO1R/JUNO receptor on egg. The IZUMO1:IZUMO1R/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion. The ligand-receptor interaction probably does not act as a membrane 'fusogen'. {ECO:0000269|PubMed:15759005}.
Subcellular Location	Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Tissue Specificity	Sperm-specific (at protein level). Detectable on sperm surface only after the acrosome reaction. {ECO:0000269|PubMed:15759005}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

IZUMO1 protein (His-DHFR tag) - ab127522 from Abcam Category Protein Source E. coli Species Human

IZUMO1 / IZUMO Antibody Blocking Peptide - LS-E5658 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

IZUMO1 / IZUMO Antibody Blocking Peptide - LS-E18487 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

IZUM1-Antibody-N-term-Blocking-Peptide - BP18187a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

IZUMO1 Protein Lysate (APL10891) - APL10891 from Aviva Systems Biology Category Protein Prices $219.00 Sizes 200 µg

Human IZUM1 protein - orb139230 from Biorbyt Category Protein Prices $323.00, $646.00 Sizes 20 μg, 100 μg Source Human Cells Species Human

IZUMO1 Blocking Peptide - 33R-8575 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

IZUMO1 Peptide - 8233P from ProSci Category Peptide Species Human

IZUMO1 fusion protein - Ag4008 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human IZUMO1, His tagged - IZUMO1-8591H from Creative Biomart Category Protein Source Human Cells Species Human

Recombinant Human IZUMO1, GST-tagged - IZUMO1-197H from Creative Biomart Category Protein Source E.coli Species Human

Human IZUMO1 Protein (His Tag) - 13520-H08H-100 from Sino Biological Category Protein Prices $138.00, $348.00 Sizes 20 µg, 100 µg Source Human Cells Species Human

Recombinant Human Izumo sperm-egg fusion protein 1(IZUMO1) - CSB-YP812903HU CSB-EP812903HU CSB-BP812903HU CSB-MP812903HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

IZUMO1 - TP306671 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Recombinant Human IZUMO1 Protein (His tag) - PKSH030610 from Elabscience Category Protein Source Human Cells Species Human

IZUMO1 Recombinant Protein Antigen - NBP1-83086PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

IZUMO1 Protein Lysate - orb333558 from Biorbyt Category Protein Prices $400.00 Sizes 200 μg Species Human

IZUMO1 Peptide, Human - M34GP07843H from Creative Peptides Category Peptide Source Synthetic. Species Human

Human IZUMO1 Protein (His Tag) - 13520-H08H from ABclonal Category Protein Prices $138.00, $348.00 Sizes 20 µg, 100 µg Source Human Cells Species Human

Izumo sperm-egg fusion protein 1 (IZUMO1), Recombinant Protein - MBS1327627 from MyBioSource Category Protein Prices $1,025.00, $1,025.00, $1,255.00, $1,255.00, $1,580.00, $1,580.00, $2,045.00, $2,045.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

IZUMO1, Recombinant Protein - MBS2545292 from MyBioSource Category Protein Prices $375.00, $905.00 Sizes 20 µg, 100 µg Source Human Cells

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