IZUMO1

Gene Symbol IZUMO1
Entrez Gene 284359
Alt Symbol IZUMO
Species Human
Gene Type protein-coding
Description izumo sperm-egg fusion 1
Other Description OBF|izumo sperm-egg fusion protein 1|oocyte binding/fusion factor|sperm-specific protein Izumo
Swissprots Q6Q8P6 Q8IYV9 Q6Q8P7
Accessions EAW52395 EAW52396 EAW52397 EAW52398 Q8IYV9 AB195682 BAD91012 AK301750 BAG63212 AY552609 AAS59145 AY552610 AAS59146 BC034769 AAH34769 BC050460 DQ893362 ABM84288 DQ894535 ABM85461 DQ896767 ABM87766 EU176807 ABW03608 XM_005258793 XP_005258850 XM_005258797 XP_005258854 XM_005258798 XP_005258855 XM_011526811 XP_011525113 XM_011526812 XP_011525114 XM_011526813 XP_011525115 XM_011526814 XP_011525116 XM_011526815 XP_011525117 XM_011526816 XP_011525118 XM_011526817 XP_011525119 XR_243923 XR_430196 XR_935799 NM_182575 NP_872381
Function Essential sperm cell-surface protein required for fertilization by acting as a ligand for IZUMO1R/JUNO receptor on egg. The IZUMO1:IZUMO1R/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion. The ligand-receptor interaction probably does not act as a membrane 'fusogen'. {ECO:0000269|PubMed:15759005}.
Subcellular Location Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Tissue Specificity Sperm-specific (at protein level). Detectable on sperm surface only after the acrosome reaction. {ECO:0000269|PubMed:15759005}.

IZUMO1 CRISPR/Cas9 KO Plasmid (h) - sc-404926 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

IZUMO1 HDR Plasmid (h) - sc-404926-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IZUMO1 Double Nickase Plasmid (h) - sc-404926-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IZUMO1 Double Nickase Plasmid (h2) - sc-404926-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IZUMO1 CRISPR Activation Plasmid (h) - sc-404926-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

IZUMO1 CRISPR Activation Plasmid (h2) - sc-404926-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

IZUMO1 Lentiviral Activation Particles (h) - sc-404926-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IZUMO1 Lentiviral Activation Particles (h2) - sc-404926-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IZUMO1 siRNA (h) - sc-75351 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

IZUMO1 shRNA Plasmid (h) - sc-75351-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

IZUMO1 shRNA (h) Lentiviral Particles - sc-75351-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU050491 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN10850 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10850 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

IZUMO1 siRNA (Human) - CRJ7007 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

IZUMO1, siRNA - MBS8209251 from MyBioSource

Category siRNA
Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human IZUMO1 (NM_182575.2) - SHH321835 from Creative biogene

Category siRNA
Species Reactivities Human

Human IZUMO1 siRNA - orb277508 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

IZUMO1 shRNA Plasmid (Human) - CHJ7007 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

IZUMO1 miRNA 3'UTR clone - MiUTR4H-TG11537 from Creative biogene

Species Reactivities Human
Search more