EED

Gene Symbol EED
Entrez Gene 8726
Alt Symbol HEED, WAIT1
Species Human
Gene Type protein-coding
Description embryonic ectoderm development
Other Description WD protein associating with integrin cytoplasmic tails 1|polycomb protein EED
Swissprots Q6NTH2 A8K7V5 Q86VV2 Q7LDG8 Q7LDA5 Q9UNY7 O75530 O00149
Accessions CCQ43235 EAW75129 EAW75130 EAW75131 O75530 AA811323 AF070418 AAC23685 AF078933 AAC68675 AF080227 AAC95144 AF099032 AAD08815 AI378297 AK292120 BAF84809 AK294133 BAG57461 AK301265 BAG62829 AL546955 AW263732 BC047672 AAH47672 BC062443 BC068995 AAH68995 DB086430 EU446743 ABZ92272 U90651 AAD08714 XM_005274373 XP_005274430 XM_011545329 XP_011543631 XM_011545330 XP_011543632 XM_011545331 XP_011543633 XR_247215 NM_001308007 NP_001294936 NM_003797 NP_003788 NM_152991 NP_694536
Function Polycomb group (PcG) protein. Component of the PRC2/EED- EZH2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Also recognizes 'Lys-26' trimethylated histone H1 with the effect of inhibiting PRC2 complex methyltransferase activity on nucleosomal histone H3 'Lys-27', whereas H3 'Lys-27' recognition has the opposite effect, enabling the propagation of this repressive mark. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-EZH2 complex include HOXC8, HOXA9, MYT1 and CDKN2A. {ECO:0000269|PubMed:10581039, ECO:0000269|PubMed:14532106, ECO:0000269|PubMed:15225548, ECO:0000269|PubMed:15231737, ECO:0000269|PubMed:15385962, ECO:0000269|PubMed:16357870, ECO:0000269|PubMed:18285464, ECO:0000269|PubMed:20974918, ECO:0000269|PubMed:9584199}.
Subcellular Location Nucleus. Chromosome. Note=Transiently colocalizes with XIST at inactive X chromosomes.
Tissue Specificity Expressed in brain, colon, heart, kidney, liver, lung, muscle, ovary, peripheral blood leukocytes, pancreas, placenta, prostate, spleen, small intestine, testis, thymus and uterus. Appears to be overexpressed in breast and colon cancer. {ECO:0000269|PubMed:15684044, ECO:0000269|PubMed:9584199, ECO:0000269|PubMed:9765275, ECO:0000269|PubMed:9806832, ECO:0000269|PubMed:9880543}.

Embryonic Ectoderm Development, EED, Human, ELISA Kit - E-EL-H1800 from ARP American Research Products

Category ELISA Kit
Prices $522.00
Sizes 96 t

Embryonic Ectoderm Development, Human, ELISA Kit - E01E0041 from ARP American Research Products

Category ELISA Kit
Prices $535.00, $735.00
Sizes 48 t, 96 t

Embryonic Ectoderm Development, EED, Mouse, ELISA Kit - E-EL-M0449 from ARP American Research Products

Category ELISA Kit
Prices $585.00
Sizes 96 t

Embryonic Ectoderm Development, EED, Rat, ELISA Kit - E-EL-R0360 from ARP American Research Products

Category ELISA Kit
Prices $585.00
Sizes 96 t

Embryonic Ectoderm Development, EED, Rabbit, ELISA Kit - E-EL-RB1431 from ARP American Research Products

Category ELISA Kit
Prices $585.00
Sizes 96 t

Embryonic Ectoderm Development, EED, Chicken, ELISA Kit - E-EL-Ch1302 from ARP American Research Products

Category ELISA Kit
Prices $522.00
Sizes 96 t

Embryonic Ectoderm Development, EED, Porcine, ELISA Kit - E-EL-P0148 from ARP American Research Products

Category ELISA Kit
Prices $585.00
Sizes 96 t

Embryonic Ectoderm Development, EED, Monkey, ELISA Kit - E-EL-MK1268 from ARP American Research Products

Category ELISA Kit
Prices $585.00
Sizes 96 t

Human EED ELISA Kit - HE0048 from NeoScientific

Category ELISA Kit
Prices $495.00
Sizes 96 t

Anserine EED ELISA Kit - AE0048 from NeoScientific

Category ELISA Kit
Prices $495.00
Sizes 96 t

EED, ELISA Kit - MBS2500288 from MyBioSource

Category ELISA Kit
Prices $410.00, $490.00, $2,040.00, $3,590.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 0.094ng/mL
Range 0.156-10ng/mL

Human EED(Embryonic Ectoderm Development) ELISA Kit - E-EL-H1800 from Elabscience

Category ELISA Kit
Sensitivity 0.10 ng/mL
Range 0.16—10 ng/mL

Embryonic Ectoderm Development, ELISA Kit - MBS101380 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Embryonic Ectoderm Development, ELISA Kit - MBS036689 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Embryonic Ectoderm Development, ELISA Kit - MBS037993 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Embryonic Ectoderm Development, ELISA Kit - MBS078214 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Embryonic Ectoderm Development, ELISA Kit - MBS039053 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Embryonic Ectoderm Development, ELISA Kit - MBS068025 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Embryonic Ectoderm Development, ELISA Kit - MBS731079 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Embryonic Ectoderm Development, ELISA Kit - MBS091129 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human FSA(Fetal Sulfoslycoprotein Antigen) ELISA Kit - E-EL-H1800 from Iwai North America Inc.

Category ELISA Kit
Prices $580.00
Sizes 1 kit
Sensitivity 0.1 ng/mLng/mL
Range 0.16~10 ng/mL

Human EED ELISA Kit - E012769 from Biobool

Category ELISA Kit

Human EED ELISA Kit - EHE0048 from ABclonal

Category ELISA Kit
Prices $495.00
Sizes 96 t

Embryonic Ectoderm Development (EED), ELISA Kit - MBS9374417 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
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