SPARC

Gene Symbol	SPARC
Entrez Gene	6678
Alt Symbol	ON
Species	Human
Gene Type	protein-coding
Description	secreted protein, acidic, cysteine-rich (osteonectin)
Other Description	BM-40|basement-membrane protein 40|cysteine-rich protein|osteonectin|secreted protein acidic and rich in cysteine
Swissprots	P09486 D3DQH9 Q6IBK4
Accessions	AAA60993 EAW61667 EAW61668 EAW61669 EAW61670 EAW61671 EAW61672 P09486 AK096969 AK299441 BAG61416 AK315591 BAG37963 AY545555 AAS50152 BC004974 AAH04974 BC008011 AAH08011 BC072457 AAH72457 BI602719 BQ018477 CR456799 CAG33080 D28381 BAA05747 DQ893415 ABM84341 DQ896734 ABM87733 J03040 AAA60570 Y00755 CAA68724 NM_003118 NP_003109
Function	Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity.
Subcellular Location	Secreted, extracellular space, extracellular matrix, basement membrane {ECO:0000269|PubMed:2306517, ECO:0000269|PubMed:3400777, ECO:0000269|PubMed:7495300, ECO:0000269|PubMed:9457905}. Note=In or around the basement membrane.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Osteonectin / SPARC ELISA Kit (Sandwich ELISA) - LS-F2890 from LifeSpan Bioscience Category ELISA Kit Prices $530.00 Sizes 1 plate Sensitivity 20 pg/ml Range 0.78-50 ng/ml

Human Osteonectin / SPARC ELISA Kit (Sandwich ELISA) - LS-F4331 from LifeSpan Bioscience Category ELISA Kit Prices $650.00 Sizes 1 plate Sensitivity 0.244 ng/ml Range 0.78-50 ng/ml

Rat Osteonectin / SPARC ELISA Kit (Sandwich ELISA) - LS-F4332 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 0.625 ng/ml Range 0.78-50 ng/ml

Mouse Osteonectin / SPARC ELISA Kit (Sandwich ELISA) - LS-F4333 from LifeSpan Bioscience Category ELISA Kit Prices $670.00 Sizes 1 plate Sensitivity 0.156 ng/ml Range 0.78-50 ng/ml

Human Osteonectin / SPARC ELISA Kit (Sandwich ELISA) - LS-F12653 from LifeSpan Bioscience Category ELISA Kit Prices $530.00 Sizes 1 plate Sensitivity 3.12 Range 0.78-50 ng/ml

Human SPARC Quantikine ELISA Kit - DSP00 from R&D Systems Category ELISA Kit Prices $519.00 Sizes 1 kit Sensitivity 0.269 ng/mL Range 1.6 - 50 ng/mL (Cell Culture Supernates, Serum, Platelet-poor EDTA Plasma, Platelet-poor Heparin Plasma, Human Milk)

Human SPARC DuoSet ELISA - DY941-05 from R&D Systems Category ELISA Kit Prices $299.00 Sizes 1 kit (for 5 Plates) Range 0.78 - 50 ng/mL

Quantikine Immunoassay Control Set 659 for Human SPARC - QC160 from R&D Systems Category ELISA Kit Prices $125.00 Sizes 1 each

Human SPARC ELISA Kit - orb219538 from Biorbyt Category ELISA Kit Prices $706.00 Sizes 96 test Sensitivity 20 pg/ml Range 780 pg/ml-50000 pg/ml

Human Osteonectin ELISA Kit - abx152603 from Abbexa Category ELISA Kit Sensitivity 0.246 ng/ml Range 0.625 ng/ml - 40 ng/ml

Human Osteonectin ELISA Kit - abx051842 from Abbexa Category ELISA Kit Sensitivity 0.06 ng/ml Range 0.3 ng/ml - 10 ng/ml

Osteonectin, ON, Human, ELISA Kit - E-EL-H1351 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 0.188 Range 0.313-20ng/mL

Osteonectin (ON), Human, ELISA Kit - SEA791Hu from ARP American Research Products Category ELISA Kit Prices $650.00 Sizes 96 t Sensitivity 0.235ng/mL Range 0.625-40ng/mL

Osteonectin, Human, ELISA Kit - E01O0017 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 0.1ng/ml Range 1.0-25ng/mL,

SPARC (Secreted Protein Acidic And Rich In Cysteine), Human, ELISA Kit - E-EL-H1286 from ARP American Research Products Category ELISA Kit Prices $617.40 Sizes 96 t

SPARC (SPARC), Human, ELISA Kit - CSB-EL022486HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

SPARC (SPARC), Human, ELISA Kit - E01S0394 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

SPARC, SPARC, Human, ELISA Kit - E0791h from ARP American Research Products Category ELISA Kit Prices $476.00 Sizes 96 t Range 3.12-200 ng/mL

Osteonectin, ON, Mouse, ELISA Kit - E-EL-M0867 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 1.875 Range 3.125-200ng/mL

Osteonectin, ON, Rat, ELISA Kit - E-EL-R0701 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 18.75 Range 31.25-2000pg/mL

Osteonectin, ON, Rabbit, ELISA Kit - E-EL-RB1955 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Secreted Protein Acidic And Rich In Cysteine, SPARC, Rabbit, ELISA Kit - E-EL-RB0947 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Osteonectin, ON, Chicken, ELISA Kit - E-EL-Ch0245 from ARP American Research Products Category ELISA Kit Prices $445.50 Sizes 96 t

Secreted Protein Acidic And Rich In Cysteine, SPARC, Chicken, ELISA Kit - E-EL-Ch0975 from ARP American Research Products Category ELISA Kit Prices $504.00 Sizes 96 t

Osteonectin, ON, Porcine, ELISA Kit - E-EL-P0712 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

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