SPARC

Gene Symbol	SPARC
Entrez Gene	6678
Alt Symbol	ON
Species	Human
Gene Type	protein-coding
Description	secreted protein, acidic, cysteine-rich (osteonectin)
Other Description	BM-40|basement-membrane protein 40|cysteine-rich protein|osteonectin|secreted protein acidic and rich in cysteine
Swissprots	P09486 D3DQH9 Q6IBK4
Accessions	AAA60993 EAW61667 EAW61668 EAW61669 EAW61670 EAW61671 EAW61672 P09486 AK096969 AK299441 BAG61416 AK315591 BAG37963 AY545555 AAS50152 BC004974 AAH04974 BC008011 AAH08011 BC072457 AAH72457 BI602719 BQ018477 CR456799 CAG33080 D28381 BAA05747 DQ893415 ABM84341 DQ896734 ABM87733 J03040 AAA60570 Y00755 CAA68724 NM_003118 NP_003109
Function	Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity.
Subcellular Location	Secreted, extracellular space, extracellular matrix, basement membrane {ECO:0000269|PubMed:2306517, ECO:0000269|PubMed:3400777, ECO:0000269|PubMed:7495300, ECO:0000269|PubMed:9457905}. Note=In or around the basement membrane.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-SPARC-cDNA-Clone - DC01575 from Abgent, a WuXi AppTec company Prices $409.05 Sizes 10 µg Species Human Accession BC004974

SPARC - MBS1278199 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC004974

Human SPARC ORF Clone(NM_003118.3) - CDCL176755 from Creative Biomart Species Human Accession NM_003118.3

Human Osteonectin / SPARC Gene ORF cDNA clone in cloning vector - HG10929-M from Sino Biological Species Human

Human Osteonectin / SPARC Gene ORF cDNA clone expression plasmid - HG10929-UT from Sino Biological Species Human

Human Osteonectin / SPARC Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG10929-ACG from Sino Biological Species Human

Human Osteonectin / SPARC Gene ORF cDNA clone expression plasmid, N-Flag tag - HG10929-NF from Sino Biological Species Human

Human Osteonectin / SPARC Gene ORF cDNA clone expression plasmid, N-Myc tag - HG10929-NM from Sino Biological Species Human

Human Osteonectin / SPARC Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10929-CF from Sino Biological Species Human

Human Osteonectin / SPARC Gene ORF cDNA clone expression plasmid, C-HA tag - HG10929-CY from Sino Biological Species Human

Human Osteonectin / SPARC Gene ORF cDNA clone expression plasmid, C-Myc tag - HG10929-CM from Sino Biological Species Human

Human Osteonectin / SPARC Gene ORF cDNA clone expression plasmid, N-His tag - HG10929-NH from Sino Biological Species Human

Human Osteonectin / SPARC Gene ORF cDNA clone expression plasmid, N-HA tag - HG10929-NY from Sino Biological Species Human

Human Osteonectin / SPARC Gene ORF cDNA clone expression plasmid, C-His tag - HG10929-CH from Sino Biological Species Human

Human SPARC ORF Clone (BC004974) - CDCS411155 from Creative biogene Species Human Accession P09486

Human SPARC ORF clone (NM_003118.2) - CDCB160847 from Creative biogene Species Human

Human Osteonectin / SPARC Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG10929-ACR from Sino Biological Species Human

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