MTR

Gene Symbol MTR
Entrez Gene 4548
Alt Symbol HMAG, MS, cblG
Species Human
Gene Type protein-coding
Description 5-methyltetrahydrofolate-homocysteine methyltransferase
Other Description 5-methyltetrahydrofolate-homocysteine methyltransferase 1|cobalamin-dependent methionine synthase|methionine synthase|vitamin-B12 dependent methionine synthase
Swissprots Q99713 B7ZLW7 A9Z1W4 Q99707 Q99723 B9EGF7 A1L4N8
Accessions EAW70066 EAW70067 Q99707 AK090487 AK125206 AK127317 AK294270 BAG57561 AK299904 BAG61745 AK307390 AY429553 BC015894 BC067276 BC130616 AAI30617 BC136440 AAI36441 BC144095 AAI44096 BC144097 AAI44098 BC144098 BX641132 CAE46059 CB241165 DC377743 U71285 AAC51188 U73338 AAB39704 U75743 AAB58906 XM_005273141 XP_005273198 XM_006711769 XP_006711832 XM_006711770 XP_006711833 XM_011544193 XP_011542495 XM_011544194 XP_011542496 NM_000254 NP_000245 NM_001291939 NP_001278868 NM_001291940 NP_001278869
Function Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm.
Tissue Specificity Widely expressed. Expressed at the highest levels in pancreas, heart, brain, skeletal muscle and placenta. Expressed at lower levels in lung, liver and kidney.
Top Pathways Cysteine and methionine metabolism, Selenocompound metabolism, Biosynthesis of amino acids, One carbon pool by folate

Anti-MTR antibody - ab66039 from Abcam

Prices $390.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-MTR antibody (ab66039) at 1 µg/mlLane 1 : TE 671 (Human Rhabdomyosarcoma) Whole Cell LysateLane 2 : Liver (Mouse) Tissue LysateLane 3 : Thymus (Rat) Tissue LysateLane 4 : Pancreas (Mouse) Tissue LysateLane 5 : Jurkat Whole Cell Lysate - Staurosporine Treated (24hr, 500nM)Lane 6 : HeLa Whole Cell Lysate - Staurosporine Treated (24hr, 500nM)Lane 7 : HeLa Whole Cell Lysate - Bleomycin Treated (20U/ml)Lane 8 : HeLa (Human epithelial carcinoma cell line) Whole Cell LysateLane 9 : Kidney (Mouse) Tissue LysateLane 10 : Liver (Rat) Tissue LysateLysates/proteins at 10 µg per lane.SecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilutionPerformed under reducing conditions.

Anti-MTR antibody - ab9209 from Abcam

Prices $378.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
9209 (3.8µg/ml) staining of paraffin embedded Human Adrenal Gland following Steamed antigen retrieval with citrate buffer pH 6 and AP-staining shows cytoplasm staining in the cortex.

Anti-MS / MTR Antibody (aa1154-1203) IHC-plus™ - LS-B6882 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-MTR antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6882 concentration 5 ug/ml.

Anti-MS / MTR Antibody (aa1252-1265) IHC-plus™ - LS-B9178 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-MS / MTR antibody IHC staining of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

MTR Antibody - NB100-791 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Western Blot: MTR Antibody [NB100-791] - (2ug/ml) staining of Hela lysate (RIPA buffer, 1.4E5 cells per lane). Detected by western blot using chemiluminescence.

MTR Antibody - NBP1-79285 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: MTR Antibody [NBP1-79285] - 721_B cell lysate, Antibody Titration: 0.2-1 ug/ml

MTR Antibody - NBP1-92146 from Novus Biologicals

Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: MTR Antibody [NBP1-92146] Staining of human cell line A-431 shows positivity in cytoplasm.

MTR Antibody - H00004548-A01 from Novus Biologicals

Host Mouse
Clonality Polyclonal

Anti-MTR antibody produced in rabbit - AV48473 from Sigma-Aldrich

Prices $347.50, $347.50
Sizes 50 µg, 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Cell Type: 721_B (<B>Cat. No. AV48473</B>).<BR/><B>Lanes</B><BR/>1. Antibody dilution (concentration) 1 μg/mL in cell type 721_B

Anti-MTR antibody produced in goat - SAB2500656 from Sigma-Aldrich

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-MTR: <B>Cat. No. SAB2500656</B>: (2 μg/mL) staining of HeLa lysate (RIPA buffer, 140000 cells per lane). Detected by western blot using chemiluminescence.

Anti-MTR antibody produced in rabbit - HPA044474 from Sigma-Aldrich

Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-MTR: <B>Cat. No. HPA044474</B>: Immunohistochemical staining of human pancreas shows moderate membranous and cytoplasmic positivity in exocrine glandular cells.

MTR antibody - C-terminal region (ARP48473_P050) - ARP48473_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

MTR-Antibody - AF1694a from Abgent, a WuXi AppTec company

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
AF1694a (2 µg/ml) staining of Hela lysate (RIPA buffer, 1.4E5 cells per lane). Detected by western blot using chemiluminescence.

MTR antibody, C-term - GTX89998 from GeneTex

Prices $319.00
Sizes 100 μg
Host Goat
Clonality Polyclonal
Anti-MTR antibody, C-term used in Western blot. GTX89998

MTR antibody - orb185360 from Biorbyt

Prices $255.00, $340.00
Sizes 100 μg, 200 μg
Host Rabbit
Clonality Polyclonal

MTR Antibody (OAEB01583) - OAEB01583 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

MTR antibody - 70R-5231 from Fitzgerald

Prices $345.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Methionine synthase / MTR antibody - 25896-1-AP from Acris Antibodies

Prices $270.00
Sizes 150 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of paraffin-embedded human pancreas tissue slide using 25896-1-AP( MTR Antibody) at dilution of 1:50 (under 10x lens)

Methionine synthase / MTR (C-term) antibody - AP15883PU-N from Acris Antibodies

Prices $310.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
AP15883PU-N MTR Antibody (3.8µg/ml) staining of paraffin embedded Human Adrenal Gland. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Methionine synthase / MTR antibody - H00004548-A01 from Acris Antibodies

Prices $300.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

Anti-MTR Antibody - AC21-0034 from Abcore

Prices $359.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-MTR Antibody (AMCA) - AC21-0034-01 from Abcore

Prices $495.00
Sizes 50 µg
Host Goat
Clonality Polyclonal

Anti-MTR Antibody (AP) - AC21-0034-02 from Abcore

Prices $505.00
Sizes 50 µg
Host Goat
Clonality Polyclonal

Anti-MTR Antibody (APC) - AC21-0034-03 from Abcore

Prices $515.00
Sizes 50 µg
Host Goat
Clonality Polyclonal

Anti-MTR Antibody (APC-Cy5.5) - AC21-0034-04 from Abcore

Prices $539.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
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