ALKBH3

Gene Symbol	ALKBH3
Entrez Gene	221120
Alt Symbol	ABH3, DEPC-1, DEPC1, PCA1
Species	Human
Gene Type	protein-coding
Description	alkB, alkylation repair homolog 3 (E. coli)
Other Description	alkylated DNA repair protein alkB homolog 3|alpha-ketoglutarate-dependent dioxygenase alkB homolog 3|prostate cancer antigen 1|prostate cancer antigen-1
Swissprots	Q3SYI0 Q96BU8 Q6NX57 Q96Q83 A6NDJ1
Accessions	ABA27096 CAC38593 CAG17896 EAW68078 EAW68079 Q96Q83 AB042029 BAB70508 AK125602 AK315266 BC015155 AAH15155 BC067257 AAH67257 BC103812 AAI03813 BC103813 AAI03814 BC103814 AAI03815 CD364334 DA685031 U38442 NM_139178 NP_631917
Function	Dioxygenase that repairs alkylated DNA containing 1- methyladenine (1meA) and 3-methylcytosine (3meC) by oxidative demethylation. Has a strong preference for single-stranded DNA. Able to process alkylated 3mC within double-stranded regions via its interaction with ASCC3, which promotes DNA unwinding to generate single-stranded substrate needed for ALKHB3. May also act on RNA. Requires molecular oxygen, alpha-ketoglutarate and iron. {ECO:0000269|PubMed:12486230, ECO:0000269|PubMed:12594517, ECO:0000269|PubMed:16174769, ECO:0000269|PubMed:22055184}.
Subcellular Location	Cytoplasm. Nucleus.
Tissue Specificity	Ubiquitous. Detected in heart, pancreas, skeletal muscle, thymus, testis, ovary, spleen, prostate, small intestine, peripheral blood leukocytes, urinary bladder and colon. {ECO:0000269|PubMed:12486230, ECO:0000269|PubMed:16174769, ECO:0000269|PubMed:17979886}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Alpha-ketoglutae-dependent dioxygenase alkB homolog 3 (ALKBH3), Human, ELISA Kit - E01A1395 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

ALKBH3 (Human) IP-WB Antibody Pair - H00221120-PW1 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

Human PCA-1/Yo ELISA Kit - HP0627 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Rat PCA-1/Yo ELISA Kit - RP0627 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Guinea Pig PCA-1/Yo ELISA Kit - GP0627 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Bovine PCA-1/Yo ELISA Kit - BP0627 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Canine PCA-1/Yo ELISA Kit - CP0627 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Porcine PCA-1/Yo ELISA Kit - PP0627 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Goat PCA-1/Yo ELISA Kit - GTP0627 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Rabbit PCA-1/Yo ELISA Kit - RTP0627 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Anserine PCA-1/Yo ELISA Kit - AP0627 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Human PCA-1/Yo(purkinje cell autoantibody) ELISA Kit - E-EL-H5571 from Elabscience Category ELISA Kit Sensitivity 1.88 ng/mL Range 3.13—200 ng/mL

alkB, alkylation repair homolog 3 (E. coli) , ELISA Kit - MBS9341721 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human ALKBH3 ELISA Kit - E001401 from Biobool Category ELISA Kit

Human PCA1 ELISA Kit - E002672 from Biobool Category ELISA Kit Sensitivity 1.0 ng/mL

Human PCA-1/Yo ELISA Kit - E032343 from Biobool Category ELISA Kit

Human PCA-1/Yo ELISA Kit - EHP0627 from ABclonal Category ELISA Kit Prices $495.00 Sizes 96 t

Human PCA-1/Yo(purkinje cell autoantibody) ELISAKit - E-EL-H5571 from Iwai North America Inc. Category ELISA Kit Prices $580.00 Sizes 1 kit Sensitivity 1.88 ng/mL Range 3.13~200 ng/mL

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