ALKBH3

Gene Symbol	ALKBH3
Entrez Gene	221120
Alt Symbol	ABH3, DEPC-1, DEPC1, PCA1
Species	Human
Gene Type	protein-coding
Description	alkB, alkylation repair homolog 3 (E. coli)
Other Description	alkylated DNA repair protein alkB homolog 3|alpha-ketoglutarate-dependent dioxygenase alkB homolog 3|prostate cancer antigen 1|prostate cancer antigen-1
Swissprots	Q3SYI0 Q96BU8 Q6NX57 Q96Q83 A6NDJ1
Accessions	ABA27096 CAC38593 CAG17896 EAW68078 EAW68079 Q96Q83 AB042029 BAB70508 AK125602 AK315266 BC015155 AAH15155 BC067257 AAH67257 BC103812 AAI03813 BC103813 AAI03814 BC103814 AAI03815 CD364334 DA685031 U38442 NM_139178 NP_631917
Function	Dioxygenase that repairs alkylated DNA containing 1- methyladenine (1meA) and 3-methylcytosine (3meC) by oxidative demethylation. Has a strong preference for single-stranded DNA. Able to process alkylated 3mC within double-stranded regions via its interaction with ASCC3, which promotes DNA unwinding to generate single-stranded substrate needed for ALKHB3. May also act on RNA. Requires molecular oxygen, alpha-ketoglutarate and iron. {ECO:0000269|PubMed:12486230, ECO:0000269|PubMed:12594517, ECO:0000269|PubMed:16174769, ECO:0000269|PubMed:22055184}.
Subcellular Location	Cytoplasm. Nucleus.
Tissue Specificity	Ubiquitous. Detected in heart, pancreas, skeletal muscle, thymus, testis, ovary, spleen, prostate, small intestine, peripheral blood leukocytes, urinary bladder and colon. {ECO:0000269|PubMed:12486230, ECO:0000269|PubMed:16174769, ECO:0000269|PubMed:17979886}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-ALKBH3-cDNA-Clone - DC08589 from Abgent, a WuXi AppTec company Prices $187.65 Sizes 10 µg Species Human Accession BC015155

ALKBH3 - MBS1270821 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC067257

ALKBH3 - MBS1273982 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC015155

ALKBH3 - MBS1276401 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC103812

Human ALKBH3 ORF Clone(NM_139178.3) - CDCL153644 from Creative Biomart Species Human Accession NM_139178.3

Human ALKBH3 ORF Clone(NM_139178.3) - CDCL153645 from Creative Biomart Species Human Accession NM_139178.3

Human ALKBH3 ORF Clone(NM_139178.3) - CDCL153646 from Creative Biomart Species Human Accession NM_139178.3

Human ALKBH3/ABH3 Gene ORF cDNA clone in cloning vector - HG15639-G from Sino Biological Species Human

Human ALKBH3/ABH3 Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG15639-ANG from Sino Biological Species Human

Human ALKBH3/ABH3 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG15639-NF from Sino Biological Species Human

Human ALKBH3/ABH3 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG15639-ACG from Sino Biological Species Human

Human ALKBH3/ABH3 Gene ORF cDNA clone expression plasmid - HG15639-UT from Sino Biological Species Human

Human ALKBH3/ABH3 Gene ORF cDNA clone expression plasmid, N-HA tag - HG15639-NY from Sino Biological Species Human

Human ALKBH3/ABH3 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG15639-CF from Sino Biological Species Human

Human ALKBH3/ABH3 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG15639-NM from Sino Biological Species Human

Human ALKBH3/ABH3 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG15639-CM from Sino Biological Species Human

Human ALKBH3/ABH3 Gene ORF cDNA clone expression plasmid, C-His tag - HG15639-CH from Sino Biological Species Human

Human ALKBH3/ABH3 Gene ORF cDNA clone expression plasmid, C-HA tag - HG15639-CY from Sino Biological Species Human

Human ALKBH3/ABH3 Gene ORF cDNA clone expression plasmid, N-His tag - HG15639-NH from Sino Biological Species Human

Human ALKBH3 ORF Clone (BC015155) - CDCS416855 from Creative biogene Species Human Accession Q96Q83

Human ALKBH3 ORF Clone (BC067257) - CDCS416856 from Creative biogene Species Human Accession Q96Q83

Human ALKBH3 ORF Clone (BC103812) - CDCS416857 from Creative biogene Species Human Accession Q96Q83

Human ALKBH3 ORF clone (BC103812) - CDCB157977 from Creative biogene Species Human

Human ALKBH3 Gene cDNA Clone - orb141777 from Biorbyt Prices $264.00 Sizes 10 μg Species Human

Human ALKBH3/ABH3 Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG15639-ANR from Sino Biological Species Human

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