ALKBH3

Gene Symbol ALKBH3
Entrez Gene 221120
Alt Symbol ABH3, DEPC-1, DEPC1, PCA1
Species Human
Gene Type protein-coding
Description alkB, alkylation repair homolog 3 (E. coli)
Other Description alkylated DNA repair protein alkB homolog 3|alpha-ketoglutarate-dependent dioxygenase alkB homolog 3|prostate cancer antigen 1|prostate cancer antigen-1
Swissprots Q3SYI0 Q96BU8 Q6NX57 Q96Q83 A6NDJ1
Accessions ABA27096 CAC38593 CAG17896 EAW68078 EAW68079 Q96Q83 AB042029 BAB70508 AK125602 AK315266 BC015155 AAH15155 BC067257 AAH67257 BC103812 AAI03813 BC103813 AAI03814 BC103814 AAI03815 CD364334 DA685031 U38442 NM_139178 NP_631917
Function Dioxygenase that repairs alkylated DNA containing 1- methyladenine (1meA) and 3-methylcytosine (3meC) by oxidative demethylation. Has a strong preference for single-stranded DNA. Able to process alkylated 3mC within double-stranded regions via its interaction with ASCC3, which promotes DNA unwinding to generate single-stranded substrate needed for ALKHB3. May also act on RNA. Requires molecular oxygen, alpha-ketoglutarate and iron. {ECO:0000269|PubMed:12486230, ECO:0000269|PubMed:12594517, ECO:0000269|PubMed:16174769, ECO:0000269|PubMed:22055184}.
Subcellular Location Cytoplasm. Nucleus.
Tissue Specificity Ubiquitous. Detected in heart, pancreas, skeletal muscle, thymus, testis, ovary, spleen, prostate, small intestine, peripheral blood leukocytes, urinary bladder and colon. {ECO:0000269|PubMed:12486230, ECO:0000269|PubMed:16174769, ECO:0000269|PubMed:17979886}.

ALKBH3 (B-7) - sc-376520 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ALKBH3 (B-7): sc-376520. Western blot analysis of ALKBH3 expression in K-562 (A) and DU 145 (B) whole cell lysates.

ALKBH3 (E-15) - sc-167073 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

ALKBH3 (H-270) - sc-135117 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
ALKBH3 (H-270): sc-135117. Western blot analysis of ALKBH3 expression in mouse cerebellum tissue extract.

ALKBH3 (K-15) - sc-167074 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-ALKBH3 antibody - ab93174 from Abcam

Prices $313.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-ALKBH3 antibody (ab93174) at 1/100 dilution + Mouse kidney tissue lysates at 35 µg

Anti-ALKBH3 antibody - ab56540 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-PCA1 / ALKBH3 Antibody (aa1-140, clone 10C2, Azide-free) - LS-C183489 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone 10C2

Anti-PCA1 / ALKBH3 Antibody (C-Terminus, AP) - LS-C243654 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PCA1 / ALKBH3 Antibody (C-Terminus, Biotin) - LS-C243656 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PCA1 / ALKBH3 Antibody (C-Terminus, APC) - LS-C243655 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PCA1 / ALKBH3 Antibody (C-Terminus, FITC) - LS-C243657 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PCA1 / ALKBH3 Antibody (C-Terminus, PE) - LS-C243662 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PCA1 / ALKBH3 Antibody (C-Terminus, Azide-free, HRP) - LS-C247434 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PCA1 / ALKBH3 Antibody - LS-C309422 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-PCA1 / ALKBH3 Antibody (clone 2A5-4F5) - LS-C307217 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2A5-4F5

Anti-PCA1 / ALKBH3 Antibody - LS-C309423 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PCA1 / ALKBH3 Antibody (aa1-140) - LS-C326828 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PCA1 / ALKBH3 Antibody (aa2-95) - LS-C178539 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PCA1 / ALKBH3 Antibody - LS-C341882 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PCA1 / ALKBH3 Antibody - LS-C334307 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using ALKBH3 antibody.

Anti-PCA1 / ALKBH3 Antibody (aa242-269) - LS-C156282 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human prostate carcinoma reacted with ALKBH3 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Anti-PCA1 / ALKBH3 Antibody - LS-C155114 from LifeSpan Bioscience

Prices $245.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)

Anti-PCA1 / ALKBH3 Antibody (aa216-265) IHC-plus™ - LS-B5865 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-ALKBH3 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5865 concentration 5 ug/ml.

ALKBH3 Antibody - NBP1-84274 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ALKBH3 Antibody - NBP1-57586 from Novus Biologicals

Prices $369.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western Blot: ALKBH3 Antibody [NBP1-57586] - Human Muscle lysate, concentration 0.2-1 ug/ml.
Search more