ALKBH3

Gene Symbol	ALKBH3
Entrez Gene	221120
Alt Symbol	ABH3, DEPC-1, DEPC1, PCA1
Species	Human
Gene Type	protein-coding
Description	alkB, alkylation repair homolog 3 (E. coli)
Other Description	alkylated DNA repair protein alkB homolog 3|alpha-ketoglutarate-dependent dioxygenase alkB homolog 3|prostate cancer antigen 1|prostate cancer antigen-1
Swissprots	Q3SYI0 Q96BU8 Q6NX57 Q96Q83 A6NDJ1
Accessions	ABA27096 CAC38593 CAG17896 EAW68078 EAW68079 Q96Q83 AB042029 BAB70508 AK125602 AK315266 BC015155 AAH15155 BC067257 AAH67257 BC103812 AAI03813 BC103813 AAI03814 BC103814 AAI03815 CD364334 DA685031 U38442 NM_139178 NP_631917
Function	Dioxygenase that repairs alkylated DNA containing 1- methyladenine (1meA) and 3-methylcytosine (3meC) by oxidative demethylation. Has a strong preference for single-stranded DNA. Able to process alkylated 3mC within double-stranded regions via its interaction with ASCC3, which promotes DNA unwinding to generate single-stranded substrate needed for ALKHB3. May also act on RNA. Requires molecular oxygen, alpha-ketoglutarate and iron. {ECO:0000269|PubMed:12486230, ECO:0000269|PubMed:12594517, ECO:0000269|PubMed:16174769, ECO:0000269|PubMed:22055184}.
Subcellular Location	Cytoplasm. Nucleus.
Tissue Specificity	Ubiquitous. Detected in heart, pancreas, skeletal muscle, thymus, testis, ovary, spleen, prostate, small intestine, peripheral blood leukocytes, urinary bladder and colon. {ECO:0000269|PubMed:12486230, ECO:0000269|PubMed:16174769, ECO:0000269|PubMed:17979886}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human ALKBH3 full length protein - ab105620 from Abcam Category Protein Prices $235.00, $866.00 Sizes 100 µg, 500 µg Source E. coli Species Human

Human ALKBH3 full length protein - ab124851 from Abcam Category Protein Prices $188.00 Sizes 20 µg Source E. coli Species Human

PCA1 / ALKBH3 Antibody Blocking Peptide - LS-E9720 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PCA1 / ALKBH3 Antibody Blocking Peptide - LS-E20031 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ALKBH3 Recombinant Protein - H00221120-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human ALKBH3 Protein - NBP1-51051 from Novus Biologicals Category Protein Prices $269.00, $729.00 Sizes 100 µg, 500 µg Source E. coli Species Human

ALKBH3-Antibody-C-term-Blocking-Peptide - BP8682b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human ALKBH3 protein - orb246611 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

Human ALKBH3 protein - orb167882 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Species Human

ALKBH3 Blocking Peptide - 33R-2593 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

ALKBH3 protein (His tag) - 80R-1739 from Fitzgerald Category Protein Prices $255.00 Sizes 100 µg Source E.coli

ALKBH3 / DEPC1 (1-286, His-tag) - AR09921PU-L from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

ALKBH3 / DEPC1 (1-286, His-tag) - AR09921PU-N from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

ALKBH3 / DEPC1 - H00221120-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

ALKBH3 / DEPC1 - H00221120-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

ALKB Alkylation Repair Homolog 3, Human Recombinant - 228-12253-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Source Escherichia Coli. Species Human

ALKBH3, 1-286aa, Human, His tag, E.coli - 01-2191-3 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

ALKBH3 fusion protein - ag2982 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

ALKBH3 Human - ENPS-108 from NeoScientific Category Protein Prices $65.00, $169.00, $3,510.00 Sizes 5 µg, 20 µg, 1 mg Source Escherichia Coli. Species Human

Recombinant Human ALKB Alkylation Repair Homolog 3 Protein - BP002580-ENZ-101 from Syd Labs Category Protein Prices $160.00, $2,700.00 Sizes 20 µg, 1 mg Source E. coli-derived. Species Human

ALKBH3 Human Protein - GWB-BSP128 from Genway Biotech Category Protein Prices $75.00, $165.00, $3,230.00 Sizes 5 μg, 20 μg, 1000 μg Source Escherichia Coli. Species Human

ALKBH3, 1-286aa, Recombinant Protein - GWB-P1057D from Genway Biotech Category Protein Prices $300.00, $900.00 Sizes 100 μg, 500 μg Source E.coli Species Human

Recombinant Human ALKBH3, His-tagged - ALKBH3-26501TH from Creative Biomart Category Protein Source E. coli

Recombinant Human Alpha-Ketoglutarate-Dependent Dioxygenase AlkB Homolog 3, His-tagged - ALKBH3-970H from Creative Biomart Category Protein

Recombinant Human ALKBH3, GST-tagged - ALKBH3-9584H from Creative Biomart Category Protein Source E.coli Species Human

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