HEMGN

Gene Symbol HEMGN
Entrez Gene 55363
Alt Symbol CT155, EDAG, EDAG-1, NDR
Species Human
Gene Type protein-coding
Description hemogen
Other Description erythroid differentiation-associated gene protein|hemopoietic gene protein|negative differentiation regulator protein
Swissprots Q9NPC0 Q6XAR3 Q9BXL5 Q86XY5
Accessions EAW58861 EAW58862 EAW58863 Q9BXL5 AF116617 AAF71041 AF130060 AAG35488 AF228713 AAF67133 AF306681 AF306682 AF306683 AF322875 AAK26295 AK292441 BAF85130 AL833094 AY244805 AAP75762 AY255672 AAP81221 BC048324 AAH48324 BG571634 BG717036 DA485094 HY026328 XM_005252086 XP_005252143 XM_011518845 XP_011517147 XM_011518846 XP_011517148 NM_018437 NP_060907 NM_197978 NP_932095
Function Regulates the proliferation and differentiation of hematopoietic cells. Overexpression block the TPA-induced megakaryocytic differentiation in the K562 cell model. May also prevent cell apoptosis through the activation of the nuclear factor-kappa B (NF-kB). {ECO:0000269|PubMed:14730214, ECO:0000269|PubMed:15332117, ECO:0000269|PubMed:15920494}.
Subcellular Location Nucleus {ECO:0000269|PubMed:14730214}.
Tissue Specificity Expressed in hematopoietic precursor cells, thyroid and spermatids (at protein level). Expressed in bone marrow, testis, thymus. Expressed in prostate cancer and ovarian cancer. Also expressed in thymus and thyroid tumors, non-Hodgkin lymphoma, various leukemia cell lines, peripheral blood mononuclear cells (PBMCs) and bone marrow mononuclear cells (BMMCs) of patients with leukemia. {ECO:0000269|PubMed:11404085, ECO:0000269|PubMed:14648837, ECO:0000269|PubMed:14730214, ECO:0000269|PubMed:15332117, ECO:0000269|PubMed:15920494, ECO:0000269|PubMed:23436708}.

Hemogen (D-4) - sc-393386 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Hemogen (D-4): sc-393386. Western blot analysis of Hemogen expression in K-562 (A), Jurkat (B), HEL 92.1.7 (C) and MEG-01 (D) nuclear extracts.

Hemogen (C-7) - sc-393416 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Hemogen (C-7): sc-393416. Western blot analysis of Hemogen expression in K-562 (A) and Jurkat (B) nuclear extracts.

Hemogen (Y-20) - sc-66242 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Hemogen (Y-20): sc-66242. Western blot analysis of Hemogen expression in K-562 (A), HEL 92.1.7 (B), Jurkat (C) and MEG-01 (D) nuclear extracts.

Hemogen (E-20) - sc-66234 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Hemogen (H-300) - sc-68361 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Hemogen (C-20) - sc-66232 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Hemogen (M-180) - sc-68360 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Hemogen (M-180): sc-68360. Western blot analysis of Hemogen expression in mouse lymph node tissue extract.

Anti-Hemogen antibody - ab66550 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Hemogen antibody (ab66550) at 1 µg/mlLane 1 : Testis (Human) Tissue Lysate - adult normal tissue (ab30257)Lane 2 : Ovary (Human) Tissue Lysate - adult normal tissue (ab30222)Lane 3 : Pancreas (Human) Tissue Lysate - adult normal tissue (ab29816)Lane 4 : Lymph node (Human) Tissue Lysate - adult normal tissue (ab29871)Lysates/proteins at 10 µg per lane.SecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilutionPerformed under reducing conditions.

Anti-Hemogen antibody - ab108430 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Hemogen antibody (ab108430) at 1 µg/ml + HT10180 cell lysate at 10 µg

Anti-EDAG / HEMGN Antibody (N-Terminus) - LS-C117242 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
HEMGN antibody LS-C117242 Western blot of HT1080 cell lysate.

Anti-EDAG / HEMGN Antibody (aa420-449) - LS-C159820 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
HEMGN Antibody western blot of A549 cell line lysates (35 ug/lane). The HEMGN antibody detected the HEMGN protein (arrow).

Anti-EDAG / HEMGN Antibody (aa260-484, clone 2D7) - LS-C338501 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2D7
IHC of paraffin-embedded Human liver tissue using anti-HEMGN mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).

Anti-EDAG / HEMGN Antibody (aa420-449, AP) - LS-C246737 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-EDAG / HEMGN Antibody (aa420-449, APC) - LS-C246738 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-EDAG / HEMGN Antibody (aa420-449, Biotin) - LS-C246739 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-EDAG / HEMGN Antibody (aa420-449, PE) - LS-C236169 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-EDAG / HEMGN Antibody (aa419-449) - LS-C321921 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-EDAG / HEMGN Antibody (aa420-449, Azide-free, HRP) - LS-C249176 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-EDAG / HEMGN Antibody (aa420-449, FITC) - LS-C246740 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Hemogen Antibody - NBP1-84909 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Hemogen Antibody [NBP1-84909] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-261

Hemogen Antibody - NBP1-84908 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Hemogen Antibody [NBP1-84908] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Negative control (vector only transfected HEK293T lysate). Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).

Hemogen Antibody - NBP1-84907 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: Hemogen Antibody [NBP1-84907] - Staining of human cell line U-251 MG shows positivity in plasma membrane and cytoplasm.

Hemogen/EDAG Polyclonal Antibody - bs-12303R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Hemogen/EDAG Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-12303R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Hemogen/EDAG Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-12303R-A488 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Search more