HEMGN

Gene Symbol HEMGN
Entrez Gene 55363
Alt Symbol CT155, EDAG, EDAG-1, NDR
Species Human
Gene Type protein-coding
Description hemogen
Other Description erythroid differentiation-associated gene protein|hemopoietic gene protein|negative differentiation regulator protein
Swissprots Q9NPC0 Q6XAR3 Q9BXL5 Q86XY5
Accessions EAW58861 EAW58862 EAW58863 Q9BXL5 AF116617 AAF71041 AF130060 AAG35488 AF228713 AAF67133 AF306681 AF306682 AF306683 AF322875 AAK26295 AK292441 BAF85130 AL833094 AY244805 AAP75762 AY255672 AAP81221 BC048324 AAH48324 BG571634 BG717036 DA485094 HY026328 XM_005252086 XP_005252143 XM_011518845 XP_011517147 XM_011518846 XP_011517148 NM_018437 NP_060907 NM_197978 NP_932095
Function Regulates the proliferation and differentiation of hematopoietic cells. Overexpression block the TPA-induced megakaryocytic differentiation in the K562 cell model. May also prevent cell apoptosis through the activation of the nuclear factor-kappa B (NF-kB). {ECO:0000269|PubMed:14730214, ECO:0000269|PubMed:15332117, ECO:0000269|PubMed:15920494}.
Subcellular Location Nucleus {ECO:0000269|PubMed:14730214}.
Tissue Specificity Expressed in hematopoietic precursor cells, thyroid and spermatids (at protein level). Expressed in bone marrow, testis, thymus. Expressed in prostate cancer and ovarian cancer. Also expressed in thymus and thyroid tumors, non-Hodgkin lymphoma, various leukemia cell lines, peripheral blood mononuclear cells (PBMCs) and bone marrow mononuclear cells (BMMCs) of patients with leukemia. {ECO:0000269|PubMed:11404085, ECO:0000269|PubMed:14648837, ECO:0000269|PubMed:14730214, ECO:0000269|PubMed:15332117, ECO:0000269|PubMed:15920494, ECO:0000269|PubMed:23436708}.

HEMGN 293 Cell Lysate - 402349 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

Hemogen Overexpression Lysate (Native) - NBL1-11503 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: Hemogen Overexpression Lysate (Adult Normal) [NBL1-11503] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Hemogen.

Hemogen (h): 293T Lysate - sc-115998 from Santa Cruz Biotechnology

Category Cell Lysate
Prices $205.00
Sizes 100 µg/200 µl
Species Human

HEMGN Over-expression Lysate Product - GWB-D5B90C from Genway Biotech

Category Cell Lysate
Prices $346.00
Sizes 100 µg
Species Human

Hemogen Overexpression Lysate (Native) - NBP2-04749 from Novus Biologicals

Category Cell Lysate
Prices $529.00
Sizes 100 µg
Western Blot: Hemogen Overexpression Lysate (Adult Normal) [NBP2-04749] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Hemogen.

Panoply™ Human HEMGN Knockdown Stable Cell Line - CSC-DC006933 from Creative biogene

Category Cell Line
Species Human
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