HEMGN

Gene Symbol	HEMGN
Entrez Gene	55363
Alt Symbol	CT155, EDAG, EDAG-1, NDR
Species	Human
Gene Type	protein-coding
Description	hemogen
Other Description	erythroid differentiation-associated gene protein|hemopoietic gene protein|negative differentiation regulator protein
Swissprots	Q9NPC0 Q6XAR3 Q9BXL5 Q86XY5
Accessions	EAW58861 EAW58862 EAW58863 Q9BXL5 AF116617 AAF71041 AF130060 AAG35488 AF228713 AAF67133 AF306681 AF306682 AF306683 AF322875 AAK26295 AK292441 BAF85130 AL833094 AY244805 AAP75762 AY255672 AAP81221 BC048324 AAH48324 BG571634 BG717036 DA485094 HY026328 XM_005252086 XP_005252143 XM_011518845 XP_011517147 XM_011518846 XP_011517148 NM_018437 NP_060907 NM_197978 NP_932095
Function	Regulates the proliferation and differentiation of hematopoietic cells. Overexpression block the TPA-induced megakaryocytic differentiation in the K562 cell model. May also prevent cell apoptosis through the activation of the nuclear factor-kappa B (NF-kB). {ECO:0000269|PubMed:14730214, ECO:0000269|PubMed:15332117, ECO:0000269|PubMed:15920494}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:14730214}.
Tissue Specificity	Expressed in hematopoietic precursor cells, thyroid and spermatids (at protein level). Expressed in bone marrow, testis, thymus. Expressed in prostate cancer and ovarian cancer. Also expressed in thymus and thyroid tumors, non-Hodgkin lymphoma, various leukemia cell lines, peripheral blood mononuclear cells (PBMCs) and bone marrow mononuclear cells (BMMCs) of patients with leukemia. {ECO:0000269|PubMed:11404085, ECO:0000269|PubMed:14648837, ECO:0000269|PubMed:14730214, ECO:0000269|PubMed:15332117, ECO:0000269|PubMed:15920494, ECO:0000269|PubMed:23436708}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Hemogen full length protein - ab163085 from Abcam Category Protein Source Wheat germ Species Human

Human Hemogen peptide - ab66549 from Abcam Category Peptide

EDAG / HEMGN Antibody Blocking Peptide - LS-E2213 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

EDAG / HEMGN Antibody Blocking Peptide - LS-E21120 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Hemogen Protein - H00055363-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

HEMGN-Antibody-C-term-Blocking-Peptide - BP13136b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

HEMGN Blocking Peptide - 33R-5847 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Hemogen - H00055363-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

HEMGN fusion protein - Ag13193 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

HEMGN fusion protein - Ag11793 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human HEMGN, GST-tagged - HEMGN-13733H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Hemogen (HEMGN) - RPH917Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Hemogen (HEMGN) - RPH917Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Hemogen(HEMGN) - CSB-YP010284HU CSB-EP010284HU CSB-BP010284HU CSB-MP010284HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Hemogen (transcript variant 1) - TP308367 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Hemogen (transcript variant 2) - TP314122 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Hemogen Recombinant Protein Antigen - NBP1-84909PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Hemogen Recombinant Protein Antigen - NBP1-84908PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Hemogen Recombinant Protein Antigen - NBP1-84907PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

HEMGN-Blocking-Peptide-C-term - BP21062a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

HEMGN Peptide, Human - M34GP06933H from Creative Peptides Category Peptide Source Synthetic. Species Human

Hemogen (HEMGN), Recombinant Protein - MBS1370851 from MyBioSource Category Protein Prices $1,270.00, $1,270.00, $1,490.00, $1,490.00, $2,075.00, $2,075.00, $2,540.00, $2,540.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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