HEMGN

Gene Symbol	HEMGN
Entrez Gene	55363
Alt Symbol	CT155, EDAG, EDAG-1, NDR
Species	Human
Gene Type	protein-coding
Description	hemogen
Other Description	erythroid differentiation-associated gene protein|hemopoietic gene protein|negative differentiation regulator protein
Swissprots	Q9NPC0 Q6XAR3 Q9BXL5 Q86XY5
Accessions	EAW58861 EAW58862 EAW58863 Q9BXL5 AF116617 AAF71041 AF130060 AAG35488 AF228713 AAF67133 AF306681 AF306682 AF306683 AF322875 AAK26295 AK292441 BAF85130 AL833094 AY244805 AAP75762 AY255672 AAP81221 BC048324 AAH48324 BG571634 BG717036 DA485094 HY026328 XM_005252086 XP_005252143 XM_011518845 XP_011517147 XM_011518846 XP_011517148 NM_018437 NP_060907 NM_197978 NP_932095
Function	Regulates the proliferation and differentiation of hematopoietic cells. Overexpression block the TPA-induced megakaryocytic differentiation in the K562 cell model. May also prevent cell apoptosis through the activation of the nuclear factor-kappa B (NF-kB). {ECO:0000269|PubMed:14730214, ECO:0000269|PubMed:15332117, ECO:0000269|PubMed:15920494}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:14730214}.
Tissue Specificity	Expressed in hematopoietic precursor cells, thyroid and spermatids (at protein level). Expressed in bone marrow, testis, thymus. Expressed in prostate cancer and ovarian cancer. Also expressed in thymus and thyroid tumors, non-Hodgkin lymphoma, various leukemia cell lines, peripheral blood mononuclear cells (PBMCs) and bone marrow mononuclear cells (BMMCs) of patients with leukemia. {ECO:0000269|PubMed:11404085, ECO:0000269|PubMed:14648837, ECO:0000269|PubMed:14730214, ECO:0000269|PubMed:15332117, ECO:0000269|PubMed:15920494, ECO:0000269|PubMed:23436708}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human EDAG / HEMGN ELISA Kit (Sandwich ELISA) - LS-F8356 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.052 ng/ml Range 0.156-10 ng/ml

Human Hemogen ELISA Kit - abx151787 from Abbexa Category ELISA Kit Sensitivity 0.052 ng/ml Range 0.156 ng/ml - 10 ng/ml

Hemogen (HEMGN), Human, ELISA Kit - SEH917Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.052ng/mL Range 0.156-10ng/mL

Hemogen, ELISA Kit - MBS052253 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Hemogen, ELISA Kit - MBS086307 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Hemogen, ELISA Kit - MBS049188 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Hemogen, ELISA Kit - MBS089736 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Hemogen, ELISA Kit - MBS064409 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Hemogen, ELISA Kit - MBS075171 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Hemogen, ELISA Kit - MBS077758 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Hemogen (HEMGN), ELISA Kit - MBS2023836 from MyBioSource Category ELISA Kit Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of human HEMGN is typically less than 0.052ng/mL. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined by adding two standard deviations to the mean optical density value of twenty zero standard replicates and calculating the corresponding concentration. Range 0.156-10ng/mL

ELISA Kit for Hemogen (HEMGN) - SEH917Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.052ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

ELISA Kit for Hemogen (HEMGN) - SEH917Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.052ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA's were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Human Hemogen (HEMGN) ELISA Kit - EKU04710 from Biomatik Category ELISA Kit Prices $735.00, $3,234.00, $5,880.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 0.052 ng/mL Range 0.156-10 ng/mL

Hemogen (HEMGN), Human, ELISA Kit - DL-HEMGN-Hu from ARP American Research Products Category ELISA Kit Prices $655.00 Sizes 96 t Range 0.156-10 ng/mL

Human HEMGN ELISA Kit - E018175 from Biobool Category ELISA Kit Sensitivity The minimum detectable dose of human HEMGN is typically less than 0.052ng/mL. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined by add

HEMGN ELISA Kit (Human) (OKDD00305) - OKDD00305 from Aviva Systems Biology Category ELISA Kit Prices $580.00 Sizes 96 wells Sensitivity < 0.052 ng/mL Range 0.156-10 ng/mL

Hemogen (HEMGN), ELISA Kit - MBS454516 from MyBioSource Category ELISA Kit Prices $415.00, $550.00, $2,425.00, $4,710.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity <0.052ng/mL Range 0.156-10ng/mL

Hemogen (HEMGN), ELISA Kit - MBS9378513 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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