HEMGN

Gene Symbol HEMGN
Entrez Gene 55363
Alt Symbol CT155, EDAG, EDAG-1, NDR
Species Human
Gene Type protein-coding
Description hemogen
Other Description erythroid differentiation-associated gene protein|hemopoietic gene protein|negative differentiation regulator protein
Swissprots Q9NPC0 Q6XAR3 Q9BXL5 Q86XY5
Accessions EAW58861 EAW58862 EAW58863 Q9BXL5 AF116617 AAF71041 AF130060 AAG35488 AF228713 AAF67133 AF306681 AF306682 AF306683 AF322875 AAK26295 AK292441 BAF85130 AL833094 AY244805 AAP75762 AY255672 AAP81221 BC048324 AAH48324 BG571634 BG717036 DA485094 HY026328 XM_005252086 XP_005252143 XM_011518845 XP_011517147 XM_011518846 XP_011517148 NM_018437 NP_060907 NM_197978 NP_932095
Function Regulates the proliferation and differentiation of hematopoietic cells. Overexpression block the TPA-induced megakaryocytic differentiation in the K562 cell model. May also prevent cell apoptosis through the activation of the nuclear factor-kappa B (NF-kB). {ECO:0000269|PubMed:14730214, ECO:0000269|PubMed:15332117, ECO:0000269|PubMed:15920494}.
Subcellular Location Nucleus {ECO:0000269|PubMed:14730214}.
Tissue Specificity Expressed in hematopoietic precursor cells, thyroid and spermatids (at protein level). Expressed in bone marrow, testis, thymus. Expressed in prostate cancer and ovarian cancer. Also expressed in thymus and thyroid tumors, non-Hodgkin lymphoma, various leukemia cell lines, peripheral blood mononuclear cells (PBMCs) and bone marrow mononuclear cells (BMMCs) of patients with leukemia. {ECO:0000269|PubMed:11404085, ECO:0000269|PubMed:14648837, ECO:0000269|PubMed:14730214, ECO:0000269|PubMed:15332117, ECO:0000269|PubMed:15920494, ECO:0000269|PubMed:23436708}.

Hemogen CRISPR/Cas9 KO Plasmid (h) - sc-417669 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Hemogen HDR Plasmid (h) - sc-417669-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Hemogen Double Nickase Plasmid (h) - sc-417669-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Hemogen Double Nickase Plasmid (h2) - sc-417669-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Hemogen CRISPR Activation Plasmid (h) - sc-417669-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Hemogen CRISPR Activation Plasmid (h2) - sc-417669-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Hemogen Lentiviral Activation Particles (h) - sc-417669-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Hemogen Lentiviral Activation Particles (h2) - sc-417669-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Hemogen siRNA (h) - sc-61859 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Hemogen shRNA Plasmid (h) - sc-61859-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Hemogen shRNA (h) Lentiviral Particles - sc-61859-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU050671 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN9971 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9971 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR05075 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr05075

HEMGN siRNA (Human) - CRJ0689 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

HEMGN - MBS8202036 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human HEMGN (NM_197978.1) - SHH311489 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human HEMGN(NM_018437.3) - SHH118163 from Creative biogene

Category siRNA
Species Reactivities Human

Human HEMGN siRNA - orb271190 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

HEMGN shRNA Plasmid (Human) - CHJ0689 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

HEMGN miRNA 3'UTR clone - MiUTR1H-04456 from Creative biogene

Species Reactivities Human

HEMGN miRNA 3'UTR clone - MiUTR3H-11428 from Creative biogene

Species Reactivities Human
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