PPP1R15A

Gene Symbol	PPP1R15A
Entrez Gene	23645
Alt Symbol	GADD34
Species	Human
Gene Type	protein-coding
Description	protein phosphatase 1, regulatory subunit 15A
Other Description	growth arrest and DNA damage-inducible protein GADD34|growth arrest and DNA-damage-inducible 34|myeloid differentiation primary response protein MyD116 homolog|protein phosphatase 1 regulatory subunit 15A|protein phosphatase 1, regulatory (inhibitor) subunit 15A
Swissprots	O75807 Q9NVU6 Q6IA96 B4DKQ3
Accessions	CBX47609 EAW52409 O75807 AK001361 BAA91649 AK225632 AK296668 BAG59265 AK297615 BAG59994 AK298765 BAG60907 AK311366 BC003067 AAH03067 CR457259 CAG33540 DA484808 DQ891855 ABM82781 EU176641 ABW03442 U83981 AAC25631 NM_014330 NP_055145
Function	Recruits the serine/threonine-protein phosphatase PP1 to dephosphorylate the translation initiation factor eIF-2A/EIF2S1, thereby reversing the shut-off of protein synthesis initiated by stress-inducible kinases and facilitating recovery of cells from stress. Down-regulates the TGF-beta signaling pathway by promoting dephosphorylation of TGFB1 by PP1. May promote apoptosis by inducing TP53 phosphorylation on 'Ser-15'. {ECO:0000269|PubMed:11564868, ECO:0000269|PubMed:12556489, ECO:0000269|PubMed:14635196, ECO:0000269|PubMed:14718519, ECO:0000269|PubMed:8139541}.
Subcellular Location	Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side {ECO:0000269|PubMed:12556489, ECO:0000269|PubMed:21518769}. Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side {ECO:0000269|PubMed:21518769}. Note=Associates with membranes via an N-terminal amphipathic intramembrane region. {ECO:0000269|PubMed:21518769}.
Top Pathways	Protein processing in endoplasmic reticulum

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

protein phosphatase 1, regulatory (inhibitor) subunit 15A, ELISA Kit - MBS9330796 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human PPP1R15A ELISA Kit - E031698 from Biobool Category ELISA Kit

anti-PPP1R15A / GADD34 antibody - ARG63153 from Arigo Biolaboratories Category ELISA Kit

Protein Phosphatase 1 Regulatory Subunit 15A (PPP1R15A), ELISA Kit - MBS9357691 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Protein Phosphatase 1 Regulatory Subunit 15A (PPP1R15A), ELISA Kit - MBS9358552 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Protein Phosphatase 1 Regulatory Subunit 15A (PPP1R15A), ELISA Kit - MBS9353065 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Protein Phosphatase 1 Regulatory Subunit 15A (PPP1R15A), ELISA Kit - MBS9346461 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Protein Phosphatase 1 Regulatory Subunit 15A (PPP1R15A), ELISA Kit - MBS9358198 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Protein Phosphatase 1 Regulatory Subunit 15A (PPP1R15A), ELISA Kit - MBS9363704 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Protein Phosphatase 1 Regulatory Subunit 15A (PPP1R15A), ELISA Kit - MBS9364293 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Protein Phosphatase 1 Regulatory Subunit 15A (PPP1R15A), ELISA Kit - MBS9358862 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Protein Phosphatase 1 Regulatory Subunit 15A (PPP1R15A), ELISA Kit - MBS9346160 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Protein Phosphatase 1 Regulatory Subunit 15A (PPP1R15A), ELISA Kit - MBS9356353 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Protein Phosphatase 1 Regulatory Subunit 15A (PPP1R15A), ELISA Kit - MBS9349949 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Protein Phosphatase 1 Regulatory Subunit 15A (PPP1R15A), ELISA Kit - MBS9346293 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Protein Phosphatase 1 Regulatory Subunit 15A (PPP1R15A), ELISA Kit - MBS9364118 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Protein Phosphatase 1 Regulatory Subunit 15A (PPP1R15A), ELISA Kit - MBS9368548 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Protein Phosphatase 1 Regulatory Subunit 15A (PPP1R15A), ELISA Kit - MBS9357948 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Protein Phosphatase 1 Regulatory Subunit 15A (PPP1R15A), ELISA Kit - MBS9343710 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Protein Phosphatase 1 Regulatory Subunit 15A (PPP1R15A), ELISA Kit - MBS9349810 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Protein Phosphatase 1 Regulatory Subunit 15A (PPP1R15A), ELISA Kit - MBS9371297 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Protein Phosphatase 1 Regulatory Subunit 15A (PPP1R15A), ELISA Kit - MBS9346749 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Protein Phosphatase 1 Regulatory Subunit 15A (PPP1R15A), ELISA Kit - MBS9343500 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Protein Phosphatase 1 Regulatory Subunit 15A (PPP1R15A), ELISA Kit - MBS9350217 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Rat PPP1R15A / GADD34 ELISA Kit (Sandwich ELISA) - LS-F39612 from LifeSpan Bioscience Category ELISA Kit Sensitivity 0.118 Range 0.156-10 ng/ml

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