MUS81

Gene Symbol MUS81
Entrez Gene 80198
Alt Symbol SLX3
Species Human
Gene Type protein-coding
Description MUS81 structure-specific endonuclease subunit
Other Description MUS81 endonuclease homolog|SLX3 structure-specific endonuclease subunit homolog|crossover junction endonuclease MUS81
Swissprots Q9H7D9 Q96NY9
Accessions EAW74453 EAW74454 Q96NY9 AF425646 AAL28065 AK024665 BAB14953 AK095326 AK126820 BAG54375 AK223564 BAD97284 AL353934 CAH56369 BC009999 AAH09999 BI816797 DA449863 XM_005274307 XP_005274364 XM_011545269 XP_011543571 XM_011545270 XP_011543572 XM_011545271 XP_011543573 XR_247212 XR_950067 NM_025128 NP_079404
Function Interacts with EME1 and EME2 to form a DNA structure- specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication forks. {ECO:0000269|PubMed:11741546, ECO:0000269|PubMed:12374758, ECO:0000269|PubMed:12686547, ECO:0000269|PubMed:12721304, ECO:0000269|PubMed:14617801, ECO:0000269|PubMed:15805243, ECO:0000269|PubMed:17289582, ECO:0000269|PubMed:19595721, ECO:0000269|PubMed:19596235}.
Subcellular Location Nucleus, nucleolus {ECO:0000269|PubMed:11741546, ECO:0000269|PubMed:14617801, ECO:0000269|PubMed:14638871, ECO:0000269|PubMed:15805243}. Note=Recruited to foci of DNA damage in S-phase cells.
Tissue Specificity Widely expressed.
Top Pathways Homologous recombination, Fanconi anemia pathway

MUS81 (H-300) - sc-30165 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

MUS81 (B-12) - sc-376661 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
MUS81 (B-12): sc-376661. Western blot analysis of MUS81 expression in A-431 (A) and K-562 (B) nuclear extracts.

MUS81 (2G10/3) - sc-47692 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
MUS81 (2G10/3): sc-47692. Western blot analysis of MUS81 expression in A-431 nuclear extract.

MUS81 (N-20) - sc-22860 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

MUS81 (MTA30 2G10/3) - sc-53382 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
MUS81 (MTA30 2G10/3): sc-53382. Western blot analysis of MUS81 expression in K-562 nuclear extract.

Anti-Mus81 antibody - ab97391 from Abcam

Prices $376.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-Mus81 antibody (ab97391) at 1/1000 dilution + NIH-3T3 whole cell lysate at 30 µg

Anti-Mus81 antibody - ab85133 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Mus81 antibody (ab85133) at 1/500 dilution + HeLa cell lysate

Anti-Mus81 antibody [MTA30 2G10/3] - ab14387 from Abcam

Prices $394.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone MTA30 2G10/3
Anti-Mus81 antibody [MTA30 2G10/3] (ab14387) at 1/1000 dilution + HeLa cell lysate

Anti-MUS81 Antibody (clone 2G10/3) - LS-C82284 from LifeSpan Bioscience

Prices $380.00
Sizes 50 µl
Host Mouse
Clonality Monoclonal
Clone 2G10/3

Anti-MUS81 Antibody (aa276-325) - LS-C145507 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
MUS81 antibody LS-C145507 Western blot of A549 Cell lysate. Antibody concentration 1 ug/ml.

Anti-MUS81 Antibody (aa207-256) - LS-C145308 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
MUS81 antibody LS-C145308 Western blot of Jurkat Cell lysate. Antibody concentration 1 ug/ml.

Anti-MUS81 Antibody (C-Terminus) - LS-C137128 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-MUS81 Antibody (aa196-370) - LS-C185336 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunofluorescence of paraformaldehyde-fixed HeLa using MUS81 antibody at 1:100 dilution.

Mus81 Antibody - NBP1-32054 from Novus Biologicals

Prices $349.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Mus81 Antibody [NBP1-32054] - Sample (30 ug of whole cell lysate) A: Hep G2 7. 5% SDS PAGE, antibody diluted at 1:500.

Mus81 Antibody (MTA30 2G10/3) - NB100-2064 from Novus Biologicals

Prices $279.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone MTA30 2G10/3
Western Blot: Mus81 Antibody (mta30 2g10/3) [NB100-2064] - Detection of Mus81 in HeLa whole cell lysate using NB100-2064.

Mus81 Antibody - NBP2-32474 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Mus81 Antibody - H00080198-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: Mus81 Antibody [H00080198-B01] - MUS81 MaxPab polyclonal antibody (B01), Lot # 08023 WULz. Western Blot analysis of MUS81 expression in human liver.

Mus81 Antibody - NBP1-32073 from Novus Biologicals

Host Rabbit
Clonality Polyclonal
Western Blot: Mus81 Antibody [NBP1-32073] - MUS81 Antibody [NBP1-32073-(30 ug of whole cell lysate) A:MOLT4 7.5% SDS PAGE diluted at 1:1000.

Mus81 Antibody - H00080198-B01P-50ug from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-MUS81 antibody produced in rabbit - SAB2700202 from Sigma-Aldrich

Prices $326.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-MUS81: <B>Cat. No. SAB2700202</B>: Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using MUS81 antibody at 1:100 dilution.

Anti-MUS81 antibody produced in rabbit - SAB2107627 from Sigma-Aldrich

Prices $341.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-MUS81: <B>Cat. No. SAB2107627</B>: Western blot analysis of MUS81 in A549 with MUS81 (MUS81 endonuclease homolog, S. cerevisiae) antibody, against the C terminal of MUS81 (50 μg) antibody at 1.0 μg/mL.

Monoclonal Anti-Mus81 antibody produced in mouse - M1445 from Sigma-Aldrich

Prices $465.00
Sizes 200 µl
Host Mouse
Clonality Monoclonal
Clone MTA30 2G10/3

Anti-MUS81 antibody produced in rabbit - SAB2700201 from Sigma-Aldrich

Prices $326.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-MUS81: <B>Cat. No. SAB2700201</B>: Western Blot analysis of MUS81 in extracts from <B>Lanes</B><BR/>A. MOLT4 using <B>Cat. No. SAB2700201</B> at a 1:1000 dilution.

ANTI-MUS81 antibody produced in mouse - SAB1411928 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-MUS81: <B>Cat. No. SAB1411928</B>: Antibody concentration: 1-5 μg/mL. Specific band of ~61.1 kDa using human liver lysate.

MUS81 antibody - C-terminal region (ARP61405_P050) - ARP61405_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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