Gene Symbol | Gckr |
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Entrez Gene | 231103 |
Alt Symbol | GKRP |
Species | Mouse |
Gene Type | protein-coding |
Description | glucokinase regulatory protein |
Other Description | glucokinase regulator |
Swissprots | Q91X44 |
Accessions | EDL37365 EDL37366 Q91X44 AK149377 BC012412 AAH12412 XM_006503881 XP_006503944 XM_006503882 XP_006503945 XM_006503883 XP_006503946 NM_144909 NP_659158 |
Function | Inhibits glucokinase (GCK) by forming an inactive complex with this enzyme. The affinity of GCKR for GCK is modulated by fructose metabolites: GCKR with bound fructose 6- phosphate has increased affinity for GCK, while GCKR with bound fructose 1-phosphate has strongly decreased affinity for GCK and does not inhibit GCK activity (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Note=Under low glucose concentrations, GCK associates with GKRP and the inactive complex is recruited to the hepatocyte nucleus. {ECO:0000250}. |
GCKR (A-8) - sc-74552 from Santa Cruz Biotechnology
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Gckr Antibody - middle region (ARP63698_P050) - ARP63698_P050 from Aviva Systems Biology
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GCKR antibody, N-term - GTX88432 from GeneTex
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Anti-GCKR antibody - STJ71883 from St John's Laboratory Ltd
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GCKR antibody - 70R-51547 from Fitzgerald
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anti-GCKR antibody - ARG64917 from Arigo Biolaboratories |
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Glucokinase Regulatory Protein, Monoclonal Antibody - MBS2025841 from MyBioSource
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Glucokinase Regulatory Protein, Polyclonal Antibody - MBS2026570 from MyBioSource
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Gckr Antibody - middle region : Biotin (ARP63698_P050-Biotin) - ARP63698_P050-Biotin from Aviva Systems Biology
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Gckr Antibody - middle region : FITC (ARP63698_P050-FITC) - ARP63698_P050-FITC from Aviva Systems Biology
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Gckr Antibody - middle region : HRP (ARP63698_P050-HRP) - ARP63698_P050-HRP from Aviva Systems Biology
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