Gckr

Gene Symbol	Gckr
Entrez Gene	231103
Alt Symbol	GKRP
Species	Mouse
Gene Type	protein-coding
Description	glucokinase regulatory protein
Other Description	glucokinase regulator
Swissprots	Q91X44
Accessions	EDL37365 EDL37366 Q91X44 AK149377 BC012412 AAH12412 XM_006503881 XP_006503944 XM_006503882 XP_006503945 XM_006503883 XP_006503946 NM_144909 NP_659158
Function	Inhibits glucokinase (GCK) by forming an inactive complex with this enzyme. The affinity of GCKR for GCK is modulated by fructose metabolites: GCKR with bound fructose 6- phosphate has increased affinity for GCK, while GCKR with bound fructose 1-phosphate has strongly decreased affinity for GCK and does not inhibit GCK activity (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Note=Under low glucose concentrations, GCK associates with GKRP and the inactive complex is recruited to the hepatocyte nucleus. {ECO:0000250}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Mouse Gckr ORF clone (NM_144909.1) - CDCL111021 from Creative biogene Species Mouse

Mouse GCKR Gene ORF cDNA clone expression plasmid, C-Flag tag - MG5A3757-CF from Sino Biological Species Mouse

Mouse GCKR Gene ORF cDNA clone expression plasmid, N-Flag tag - MG5A3757-NF from Sino Biological Species Mouse

Mouse GCKR Gene ORF cDNA clone expression plasmid, C-HA tag - MG5A3757-CY from Sino Biological Species Mouse

Mouse GCKR Gene ORF cDNA clone expression plasmid, N-His tag - MG5A3757-NH from Sino Biological Species Mouse

Mouse GCKR Gene ORF cDNA clone expression plasmid, N-HA tag - MG5A3757-NY from Sino Biological Species Mouse

Mouse GCKR Gene ORF cDNA clone expression plasmid - MG5A3757-UT from Sino Biological Species Mouse

Mouse GCKR Gene ORF cDNA clone expression plasmid, C-His tag - MG5A3757-CH from Sino Biological Species Mouse

Mouse GCKR Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - MG5A3757-ACG from Sino Biological Species Mouse

Mouse GCKR Gene ORF cDNA clone expression plasmid, C-Myc tag - MG5A3757-CM from Sino Biological Species Mouse

Mouse GCKR Gene ORF cDNA clone expression plasmid, N-Myc tag - MG5A3757-NM from Sino Biological Species Mouse

Mouse GCKR Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - MG5A3757-ACR from Sino Biological Species Mouse

Mouse GCKR Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - MG5A3757-ANG from Sino Biological Species Mouse

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