| Gene Symbol | Gckr |
|---|---|
| Entrez Gene | 231103 |
| Alt Symbol | GKRP |
| Species | Mouse |
| Gene Type | protein-coding |
| Description | glucokinase regulatory protein |
| Other Description | glucokinase regulator |
| Swissprots | Q91X44 |
| Accessions | EDL37365 EDL37366 Q91X44 AK149377 BC012412 AAH12412 XM_006503881 XP_006503944 XM_006503882 XP_006503945 XM_006503883 XP_006503946 NM_144909 NP_659158 |
| Function | Inhibits glucokinase (GCK) by forming an inactive complex with this enzyme. The affinity of GCKR for GCK is modulated by fructose metabolites: GCKR with bound fructose 6- phosphate has increased affinity for GCK, while GCKR with bound fructose 1-phosphate has strongly decreased affinity for GCK and does not inhibit GCK activity (By similarity). {ECO:0000250}. |
| Subcellular Location | Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Note=Under low glucose concentrations, GCK associates with GKRP and the inactive complex is recruited to the hepatocyte nucleus. {ECO:0000250}. |
Mouse GKRP ELISA Kit - MG0195 from NeoScientific
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Mouse GKRP ELISA Kit - E054231 from Biobool
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Mouse GKRP ELISA Kit - EMG0195 from ABclonal
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Glucokinase regulatory protein, ELISA Kit - MBS2884782 from MyBioSource
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