IL12RB2

Gene Symbol	IL12RB2
Entrez Gene	3595
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	interleukin 12 receptor, beta 2
Other Description	IL-12 receptor subunit beta-2|IL-12R subunit beta-2|interleukin-12 receptor beta-2 chain|interleukin-12 receptor subunit beta-2
Swissprots	Q2M3V3 Q99665 B7ZKL9 B1AN98 F5H7L6
Accessions	AAT45456 EAX06499 EAX06500 Q99665 AK294494 BAG57715 AK300020 BAG61833 AK310837 AK316525 BAH14896 BC104772 AAI04773 BC104774 AAI04775 BC143248 BC143249 AAI43250 BC143250 BC143252 DA223630 DB126833 U64198 AAB36675 XM_005270825 XP_005270882 XM_005270827 XP_005270884 XM_005270828 XP_005270885 XM_006710617 XP_006710680 XM_011541383 XP_011539685 XM_011541384 XP_011539686 XM_011541385 XP_011539687 NM_001258214 NP_001245143 NM_001258215 NP_001245144 NM_001258216 NP_001245145 NM_001559 NP_001550 NR_047583 NR_047584
Function	Receptor for interleukin-12. This subunit is the signaling component coupling to the JAK2/STAT4 pathway. Promotes the proliferation of T-cells as well as NK cells. Induces the promotion of T-cells towards the Th1 phenotype by strongly enhancing IFN-gamma production.
Subcellular Location	Membrane; Single-pass type I membrane protein.
Tissue Specificity	Isoform 2 is expressed at similar levels in both naive and activated T-cells. {ECO:0000269|PubMed:9120388}.
Top Pathways	Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Inflammatory bowel disease (IBD)

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human IL12RB2 ELISA Kit (Sandwich ELISA) - LS-F7899 from LifeSpan Bioscience Category ELISA Kit Prices $690.00 Sizes 1 plate Sensitivity 0.053 ng/ml Range 0.156-10 ng/ml

Human IL12Rb2 ELISA Kit - abx151926 from Abbexa Category ELISA Kit Sensitivity 0.055 ng/ml Range 0.156 ng/ml - 10 ng/ml

Interleukin 12 Receptor Beta 2 (IL12Rb2), Human, ELISA Kit - SEB073Hu from ARP American Research Products Category ELISA Kit Prices $685.00 Sizes 96 t Sensitivity 0.055ng/mL Range 0.156-10ng/mL

Interleukin-12 receptor subunit beta-2 (IL12RB2), Human, ELISA Kit - CSB-EL011589HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Interleukin-12 receptor subunit beta-2 (IL12RB2), Human, ELISA Kit - E01I0433 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Custom Human IL-12 R beta 2 ELISA - ELH-IL12Rb2 from RayBiotech Category ELISA Kit Prices $615.00, $1,107.00, $2,460.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit

Interleukin 12, IL-12, ELISA Kit - MBS700980 from MyBioSource Category ELISA Kit Prices $250.00, $590.00, $855.00, $3,110.00, $5,890.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of sheep IL-12 is typically less than 7.81 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. Range 31.25 pg/ml-2000 pg/ml.

IL-12, ELISA Kit - MBS2502160 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 18.75pg/mL Range 31.25-2000pg/mL

IL-12, ELISA Kit - MBS2510359 from MyBioSource Category ELISA Kit Prices $445.00 Sizes 96 -strip-wells Sensitivity The minimum detectable dose of Mouse IL-12 is 9.375pg/mL (The sensitivity of this assay, or lowest detectable limit (LDL) was defined as the lowest protein concentration that could be differentiated from zero). Range 15.625-1000pg/mL

IL-12, ELISA Kit - MBS2507061 from MyBioSource Category ELISA Kit Prices $445.00 Sizes 96 -strip-wells Sensitivity 9.375pg/mL Range 15.625--1000pg/mL

IL-12, ELISA Kit - MBS2507081 from MyBioSource Category ELISA Kit Prices $490.00, $585.00, $2,475.00, $4,360.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 18.75pg/mL Range 31.25--2000pg/mL

IL-12, ELISA Kit - MBS2501716 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 7.5pg/mL Range 12.5--800pg/mL

IL-12, ELISA Kit - MBS2508400 from MyBioSource Category ELISA Kit Prices $445.00 Sizes 96 -strip-wells Sensitivity The minimum detectable dose of Human IL-12 is 9.375pg/mL (The sensitivity of this assay, or lowest detectable limit (LDL) was defined as the lowest protein concentration that could be differentiated from zero). Range 15.625-1000pg/mL

IL-12, ELISA Kit - MBS2511510 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 9.375pg/mL Range 15.625--1000pg/mL

IL-12, ELISA Kit - MBS2511011 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 9.375pg/mL Range 15.625--1000pg/mL

IL-12, ELISA Kit - MBS2504364 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 18.75pg/mL Range 31.25-2000pg/mL

Interleukin 12 (IL-12), ELISA Kit - MBS9310576 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Interleukin 12 receptor (IL-12R) ELISA kit, ELISA Kit - MBS934646 from MyBioSource Category ELISA Kit Prices $250.00, $550.00, $795.00, $2,890.00, $5,465.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of human IL-12R is typically less than 0.039ng/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. Range 0.156 ng/ml-10 ng/ml.

Interleukin 12 receptor subunit beta 2 (IL12RB2), ELISA Kit - MBS7236384 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

interleukin 12 receptor, beta 2, ELISA Kit - MBS934262 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Interleukin-12 receptor subunit beta-2, ELISA Kit - MBS280498 from MyBioSource Category ELISA Kit Prices $465.00, $790.00, $3,500.00, $6,655.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Interleukin-12 receptor subunit beta-2 (IL12RB2), ELISA Kit - MBS7250955 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Interleukin-12 receptor subunit beta-2 (IL12RB2), ELISA Kit - MBS7234318 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Interleukin-12 receptor subunit beta-2 (IL12RB2), ELISA Kit - MBS7220499 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Interleukin-12 receptor subunit beta-2 (IL12RB2), ELISA Kit - MBS7213882 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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