IL12RB2

Gene Symbol	IL12RB2
Entrez Gene	3595
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	interleukin 12 receptor, beta 2
Other Description	IL-12 receptor subunit beta-2|IL-12R subunit beta-2|interleukin-12 receptor beta-2 chain|interleukin-12 receptor subunit beta-2
Swissprots	Q2M3V3 Q99665 B7ZKL9 B1AN98 F5H7L6
Accessions	AAT45456 EAX06499 EAX06500 Q99665 AK294494 BAG57715 AK300020 BAG61833 AK310837 AK316525 BAH14896 BC104772 AAI04773 BC104774 AAI04775 BC143248 BC143249 AAI43250 BC143250 BC143252 DA223630 DB126833 U64198 AAB36675 XM_005270825 XP_005270882 XM_005270827 XP_005270884 XM_005270828 XP_005270885 XM_006710617 XP_006710680 XM_011541383 XP_011539685 XM_011541384 XP_011539686 XM_011541385 XP_011539687 NM_001258214 NP_001245143 NM_001258215 NP_001245144 NM_001258216 NP_001245145 NM_001559 NP_001550 NR_047583 NR_047584
Function	Receptor for interleukin-12. This subunit is the signaling component coupling to the JAK2/STAT4 pathway. Promotes the proliferation of T-cells as well as NK cells. Induces the promotion of T-cells towards the Th1 phenotype by strongly enhancing IFN-gamma production.
Subcellular Location	Membrane; Single-pass type I membrane protein.
Tissue Specificity	Isoform 2 is expressed at similar levels in both naive and activated T-cells. {ECO:0000269|PubMed:9120388}.
Top Pathways	Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Inflammatory bowel disease (IBD)

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human IL-12 R beta 2 (NP_001550) VersaClone cDNA - RDC1184 from R&D Systems Prices $499.00 Sizes 10 µg Species Human

Mouse IL-12 R beta 2 (NP_032380) VersaClone cDNA - RDC1169 from R&D Systems Prices $499.00 Sizes 10 µg Species Mouse

Human IL12RB2 cDNA clone(NM_001559.2) - CDFH009141 from Creative Biomart Species Human Accession NM_001559.2

Human IL12Rb2 ORF clone(NM_001559.2) - CDCL184753 from Creative Biomart Species Human Accession NM_001559.2

Human IL12RB2 ORF Clone(NM_001559.2) - CDCR280858 from Creative Biomart Species Human Accession NM_001559.2

Human IL12RB2 ORF Clone(NM_001559.2) - CDCR280859 from Creative Biomart Species Human Accession NM_001559.2

Human IL12RB2 ORF Clone(NM_001559.2) - CDCR281077 from Creative Biomart Species Human Accession NM_001559.2

Human IL12RB2 Gene ORF cDNA clone in cloning vector - HG10145-M from Sino Biological Species Human

Human IL12RB2 Gene ORF cDNA clone expression plasmid, N-His tag - HG10145-NH from Sino Biological Species Human

Human IL12RB2 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG10145-ACR from Sino Biological Species Human

Human IL12RB2 Gene ORF cDNA clone expression plasmid - HG10145-M-N from Sino Biological Species Human

Human IL12RB2 Gene ORF cDNA clone expression plasmid, C-HA tag - HG10145-M-Y from Sino Biological Species Human

Human IL12RB2 Gene ORF cDNA clone expression plasmid - HG10145-UT from Sino Biological Species Human

Human IL12RB2 Gene ORF cDNA clone expression plasmid, C-HA tag - HG10145-CY from Sino Biological Species Human

Human IL12Rb2 Gene cDNA Clone (full-length ORF Clone) expression ready, FLAG-tagged - HG10145-M-F from Sino Biological Species Human Accession NM_001559.2

Human IL12RB2 Gene ORF cDNA clone expression plasmid, C-His tag - HG10145-CH from Sino Biological Species Human

Human IL12RB2 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG10145-NF from Sino Biological Species Human

Human IL12RB2 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10145-CF from Sino Biological Species Human

Human IL12RB2 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG10145-NM from Sino Biological Species Human

Human IL12RB2 Gene ORF cDNA clone expression plasmid, N-HA tag - HG10145-NY from Sino Biological Species Human

Human IL12RB2 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG10145-ACG from Sino Biological Species Human

Human IL12RB2 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG10145-CM from Sino Biological Species Human

Human IL12Rb2 ORF clone(NM_001559.2) - CDCL184753 from Creative biogene Species Human

Mouse IL12RB2 ORF clone (NM_001258214.1) - CDCL120159 from Creative biogene Species Human

Mouse IL12RB2 ORF clone (NM_001258215.1) - CDCL120161 from Creative biogene Species Human

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