SELP

Gene Symbol SELP
Entrez Gene 6403
Alt Symbol CD62, CD62P, GMP140, GRMP, LECAM3, PADGEM, PSEL
Species Human
Gene Type protein-coding
Description selectin P (granule membrane protein 140kDa, antigen CD62)
Other Description CD62 antigen-like family member P|GMP-140|P-selectin|granule membrane protein 140|granulocyte membrane protein|leukocyte-endothelial cell adhesion molecule 3|platelet activation dependent granule-external membrane protein|platelet alpha-granule membrane protein
Swissprots P16109 Q8IVD1 Q5R344
Accessions AAA35910 AAC31762 AAN06828 EAW90850 EAW90851 EAW90852 EAW90853 EAW90854 P16109 AK312884 BAG35732 AY367063 AAQ67703 BC028067 AAH28067 BC068533 AAH68533 DA926598 DA994564 M25322 AAA35911 XM_005245435 XP_005245492 XM_005245436 XP_005245493 XM_005245438 XP_005245495 XM_005245439 XP_005245496 XM_005245440 XP_005245497 NM_003005 NP_002996
Function Ca(2+)-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. Mediates the interaction of activated endothelial cells or platelets with leukocytes. The ligand recognized is sialyl-Lewis X. Mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with PSGL1. {ECO:0000269|PubMed:7585950}.
Subcellular Location Membrane; Single-pass type I membrane protein.
Tissue Specificity Stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. Upon cell activation by agonists, P-selectin is transported rapidly to the cell surface.
Top Pathways Cell adhesion molecules (CAMs), Staphylococcus aureus infection, Malaria

P-Selectin (CTB201) - sc-8419 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
P-Selectin (CTB201): sc-8419. Western blot analysis of P-Selectin expression in human platelet extract.

P-Selectin (H-150) - sc-25771 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
P-Selectin (H-150): sc-25771. Western blot analysis of P-Selectin expression in mouse placenta tissue extract.

P-Selectin (C-20) - sc-6941 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
P-Selectin (C-20): sc-6941. Immunoperoxidase staining of formalin-fixed human platelets and white blood cells showing membrane staining of platelets.

P-Selectin (M-20) - sc-6943 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
P-Selectin (M-20): sc-6943. Western blot analysis of P-Selectin expression in human platelet extract.

P-Selectin (AK4) - sc-19996 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
P-Selectin (AK4) PE: sc-19996 PE. FCM analysis of human platelets. Black line histogram represents the isotype control, normal mouse IgG<sub>1</sub>: sc-2866.

P-Selectin (1 E 3) - sc-19672 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
P-Selectin (1 E 3): sc-19672. Immunoperoxidase staining of formalin-fixed human platelets and white blood cells showing membrane staining of platelets.

P-Selectin (H-2) - sc-271267 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
P-Selectin (H-2): sc-271267. Western blot analysis of P-Selectin expression in human platelet extract.

P-Selectin (P8G6) - sc-18834 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
P-Selectin (P8G6): sc-18834. Immunoperoxidase staining of formalin-fixed human platelets and white blood cells showing membrane staining of platelets.

P-Selectin (Psel.KO.2.9) - sc-101619 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
P-Selectin (Psel.KO.2.9): sc-101619. Western blot analysis of P-Selectin expression in human platelet extract.

P-Selectin (Psel.KO.2.7) - sc-101336 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal

P-Selectin (CLB/thromb/6) - sc-59769 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal

Anti-CD62P antibody - ab59738 from Abcam

Prices $378.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-CD62P antibody (ab59738) at 0.5 µg/ml + Jurkat cell lysate

Anti-CD62P antibody - ab119435 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-CD62P antibody (ab119435) at 1 µg/ml + Platelet (Human) Whole Cell Lysate at 10 µgSecondaryGoat Anti-Rabbit IgG H&L (HRP) (ab97051) at 1/10000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-CD62P antibody [AK-6] - ab6632 from Abcam

Prices $390.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone AK-6
ab6632 at 1/10 dilution staining human Renal Carcinoma tissue sections by Immunohistochemistry (Formalin-fixed paraffin-embedded sections). Folowing heat mediated antigen retrieval the tissue was stained with antibody for 12 hours and then detected using a biotinylated donkey anti-mouse IgG antibody.This image is courtesy of an Abreview submitted on 3 March 2006.See Abreview

Anti-CD62P antibody [AK-6] (FITC) - ab33279 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone AK-6

Anti-CD62P antibody [AK4] (Biotin) - ab134398 from Abcam

Prices $189.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone AK4
Flow cytometric analysis of CD62P in thrombin activated Human platelets stained with ab134398 at 2 µg per 106 cells (100 µl test volume), followed by Sav-PE.

Anti-CD62P antibody [AK4] (Phycoerythrin) - ab119104 from Abcam

Prices $372.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone AK4

Anti-CD62P antibody [AK4], prediluted (FITC) - ab134397 from Abcam

Prices $376.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone AK4
Flow cytometric analysis of CD62P in thrombin activated Human peripheral blood platelets stained with ab134397 at 20 µl for 106 cells.

Anti-CD62P antibody [AK4] - Low endotoxin, Azide free - ab119848 from Abcam

Prices $373.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone AK4

Anti-CD62P antibody [EPR1444(2)(B)] - ab178424 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR1444(2)(B)
All lanes : Anti-CD62P antibody [EPR1444(2)(B)] (ab178424) at 1/1000 dilutionLane 1 : HUVEC cell lysateLane 2 : Jurkat cell lysateLane 3 : Human placenta lysateLane 4 : Human fetal liver lysateLysates/proteins at 10 µg per lane.SecondaryGoat anti-rabbit HRP at 1/2000 dilution

Anti-CD62P antibody [EPR2146(2)] - ab182135 from Abcam

Prices $384.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR2146(2)
Western blot analysis of immunoprecipitation pellet from Human plasma immunoprecipitated using ab182135 at 1/30 dilution.  Secondary antibody Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000.

Anti-CD62P antibody (FITC) - ab73972 from Abcam

Prices $370.00
Sizes 100 µl
Host Chicken
Clonality Polyclonal

Anti-CD62P antibody [HI62P] - ab21834 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone HI62P

Anti-CD62P antibody [P.seK02,22] (PerCP) - ab91132 from Abcam

Prices $185.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone P.seK02,22

Anti-CD62P antibody [Psel.KO.2.12] - ab54426 from Abcam

Prices $372.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone Psel.KO.2.12
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