SELP

Gene Symbol	SELP
Entrez Gene	6403
Alt Symbol	CD62, CD62P, GMP140, GRMP, LECAM3, PADGEM, PSEL
Species	Human
Gene Type	protein-coding
Description	selectin P (granule membrane protein 140kDa, antigen CD62)
Other Description	CD62 antigen-like family member P|GMP-140|P-selectin|granule membrane protein 140|granulocyte membrane protein|leukocyte-endothelial cell adhesion molecule 3|platelet activation dependent granule-external membrane protein|platelet alpha-granule membrane protein
Swissprots	P16109 Q8IVD1 Q5R344
Accessions	AAA35910 AAC31762 AAN06828 EAW90850 EAW90851 EAW90852 EAW90853 EAW90854 P16109 AK312884 BAG35732 AY367063 AAQ67703 BC028067 AAH28067 BC068533 AAH68533 DA926598 DA994564 M25322 AAA35911 XM_005245435 XP_005245492 XM_005245436 XP_005245493 XM_005245438 XP_005245495 XM_005245439 XP_005245496 XM_005245440 XP_005245497 NM_003005 NP_002996
Function	Ca(2+)-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. Mediates the interaction of activated endothelial cells or platelets with leukocytes. The ligand recognized is sialyl-Lewis X. Mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with PSGL1. {ECO:0000269|PubMed:7585950}.
Subcellular Location	Membrane; Single-pass type I membrane protein.
Tissue Specificity	Stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. Upon cell activation by agonists, P-selectin is transported rapidly to the cell surface.
Top Pathways	Cell adhesion molecules (CAMs), Staphylococcus aureus infection, Malaria

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

SELP 293T Cell Transient Overexpression Lysate(Denatured) - H00006403-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

SELP 293 Cell Lysate - 408865 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

P-Selectin/CD62P Overexpression Lysate (Denatured) - H00006403-T01 from Novus Biologicals Category Cell Lysate Prices $299.00 Sizes 100 µl Species Human

P-Selectin/CD62P Overexpression Lysate (Native) - NBL1-15793 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

P-Selectin (h): 293T Lysate - sc-114655 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

SELP Over-expression Lysate Product - GWB-1D322B from Genway Biotech Category Cell Lysate Prices $445.00 Sizes 100 µg Species Human

Rhesus SELP / selectin P / P-selectin HEK293 Cell Lysate (WB positive control) - 90170-C08HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg

Human SELP / selectin P / P-selectin HEK293 Cell Lysate (WB positive control) - 13025-H08HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human SELP / selectin P / P-selectin HEK293 Cell Lysate (WB positive control) - 13025-H02HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human SELP Human Cells Transfected Lysate (positive control) (denatured) - orb174055 from Biorbyt Category Cell Lysate Prices $425.00 Sizes 300 μg Species Human

Human SELP Human Cells Transfected Lysate (positive control) (denatured) - orb174100 from Biorbyt Category Cell Lysate Prices $604.00 Sizes 300 μg Species Human

Panoply™ Human SELP Knockdown Stable Cell Line - CSC-DC013973 from Creative biogene Category Cell Line Species Human

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