Gene Symbol | SELP |
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Entrez Gene | 6403 |
Alt Symbol | CD62, CD62P, GMP140, GRMP, LECAM3, PADGEM, PSEL |
Species | Human |
Gene Type | protein-coding |
Description | selectin P (granule membrane protein 140kDa, antigen CD62) |
Other Description | CD62 antigen-like family member P|GMP-140|P-selectin|granule membrane protein 140|granulocyte membrane protein|leukocyte-endothelial cell adhesion molecule 3|platelet activation dependent granule-external membrane protein|platelet alpha-granule membrane protein |
Swissprots | P16109 Q8IVD1 Q5R344 |
Accessions | AAA35910 AAC31762 AAN06828 EAW90850 EAW90851 EAW90852 EAW90853 EAW90854 P16109 AK312884 BAG35732 AY367063 AAQ67703 BC028067 AAH28067 BC068533 AAH68533 DA926598 DA994564 M25322 AAA35911 XM_005245435 XP_005245492 XM_005245436 XP_005245493 XM_005245438 XP_005245495 XM_005245439 XP_005245496 XM_005245440 XP_005245497 NM_003005 NP_002996 |
Function | Ca(2+)-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. Mediates the interaction of activated endothelial cells or platelets with leukocytes. The ligand recognized is sialyl-Lewis X. Mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with PSGL1. {ECO:0000269|PubMed:7585950}. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Tissue Specificity | Stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. Upon cell activation by agonists, P-selectin is transported rapidly to the cell surface. |
Top Pathways | Cell adhesion molecules (CAMs), Staphylococcus aureus infection, Malaria |
CD62P (P-Selectin) Human ELISA Kit - ab100631 from Abcam
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Human SELP / P-Selectin / CD62P ELISA Kit (Sandwich ELISA) - LS-F5636 from LifeSpan Bioscience
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Human SELP / P-Selectin / CD62P ELISA Kit (Sandwich ELISA) - LS-F2544 from LifeSpan Bioscience
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Human SELP / P-Selectin / CD62P ELISA Kit (Sandwich ELISA) - LS-F475 from LifeSpan Bioscience
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Rat SELP / P-Selectin / CD62P ELISA Kit (Sandwich ELISA) - LS-F11997 from LifeSpan Bioscience
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Human SELP / P-Selectin / CD62P ELISA Kit (Sandwich ELISA) - LS-F11995 from LifeSpan Bioscience
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Mouse SELP / P-Selectin / CD62P ELISA Kit (Sandwich ELISA) - LS-F11996 from LifeSpan Bioscience
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Human P-Selectin ELISA Kit - RAB0426 from Sigma-Aldrich
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Human sP-Selectin/CD62P Luminex Performance Assay - LUCB137 from R&D Systems |
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Human P-Selectin/CD62P ELISA Kit - BBE6 from R&D Systems
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Human sP-Selectin/CD62P PharmPak (50 Plates) - PBBE6 from R&D Systems
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Human sP-Selectin/CD62P SixPak (6 Plates) - SBBE6 from R&D Systems
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Mouse sP-Selectin/CD62P Quantikine ELISA Kit - MPS00 from R&D Systems
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Human P-Selectin/CD62P DuoSet ELISA - DY137 from R&D Systems
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Mouse P-Selectin/CD62P DuoSet ELISA - DY737 from R&D Systems
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Human P Selectin ELISA kit - 55R-2122 from Fitzgerald
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Human P-Selectin ELISA Kit - 55R-1679 from Fitzgerald
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Monkey sP Selectin ELISA kit - 55R-IB49724 from Fitzgerald
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Mouse P-Selectin ELISA Kit - 55R-1680 from Fitzgerald
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Human P-selectin ELISA Kit - orb106662 from Biorbyt
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Human CD62P ELISA Kit - abx056109 from Abbexa
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Human GMP-140 ELISA Kit - abx054064 from Abbexa
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Human P-Selectin ELISA kit - abx050186 from Abbexa
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Human P-Selectin ELISA Kit - abx051719 from Abbexa
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Human P-Selectin ELISA Kit - abx051718 from Abbexa
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