SELP

Gene Symbol SELP
Entrez Gene 6403
Alt Symbol CD62, CD62P, GMP140, GRMP, LECAM3, PADGEM, PSEL
Species Human
Gene Type protein-coding
Description selectin P (granule membrane protein 140kDa, antigen CD62)
Other Description CD62 antigen-like family member P|GMP-140|P-selectin|granule membrane protein 140|granulocyte membrane protein|leukocyte-endothelial cell adhesion molecule 3|platelet activation dependent granule-external membrane protein|platelet alpha-granule membrane protein
Swissprots P16109 Q8IVD1 Q5R344
Accessions AAA35910 AAC31762 AAN06828 EAW90850 EAW90851 EAW90852 EAW90853 EAW90854 P16109 AK312884 BAG35732 AY367063 AAQ67703 BC028067 AAH28067 BC068533 AAH68533 DA926598 DA994564 M25322 AAA35911 XM_005245435 XP_005245492 XM_005245436 XP_005245493 XM_005245438 XP_005245495 XM_005245439 XP_005245496 XM_005245440 XP_005245497 NM_003005 NP_002996
Function Ca(2+)-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. Mediates the interaction of activated endothelial cells or platelets with leukocytes. The ligand recognized is sialyl-Lewis X. Mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with PSGL1. {ECO:0000269|PubMed:7585950}.
Subcellular Location Membrane; Single-pass type I membrane protein.
Tissue Specificity Stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. Upon cell activation by agonists, P-selectin is transported rapidly to the cell surface.
Top Pathways Cell adhesion molecules (CAMs), Staphylococcus aureus infection, Malaria

P-Selectin CRISPR/Cas9 KO Plasmid (h) - sc-400441 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

P-Selectin HDR Plasmid (h) - sc-400441-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

P-Selectin Double Nickase Plasmid (h) - sc-400441-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

P-Selectin Double Nickase Plasmid (h2) - sc-400441-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

P-Selectin CRISPR Activation Plasmid (h) - sc-400441-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

P-Selectin CRISPR Activation Plasmid (h2) - sc-400441-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

P-Selectin Lentiviral Activation Particles (h) - sc-400441-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

P-Selectin Lentiviral Activation Particles (h2) - sc-400441-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

P-Selectin siRNA (h) - sc-29421 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

P-Selectin shRNA Plasmid (h) - sc-29421-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

P-Selectin shRNA (h) Lentiviral Particles - sc-29421-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU039631 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN19058 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19058 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR04918 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr04918

SELP siRNA (Human) - CRH4326 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SELP - MBS8202715 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SELP (NM_003005.3) - SHH404128 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human SELP(NM_003005.3) - SHR213176 from Creative biogene

Category siRNA
Species Reactivities Human

P-Selectin CRISPR/Cas9 KO Plasmid (h2) - sc-400441-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

P-Selectin HDR Plasmid (h2) - sc-400441-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SELP shRNA Plasmid (Human) - CHH4326 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SELP miRNA 3'UTR clone - MiUTR1H-09243 from Creative biogene

Species Reactivities Human
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