SELP

Gene Symbol	SELP
Entrez Gene	6403
Alt Symbol	CD62, CD62P, GMP140, GRMP, LECAM3, PADGEM, PSEL
Species	Human
Gene Type	protein-coding
Description	selectin P (granule membrane protein 140kDa, antigen CD62)
Other Description	CD62 antigen-like family member P|GMP-140|P-selectin|granule membrane protein 140|granulocyte membrane protein|leukocyte-endothelial cell adhesion molecule 3|platelet activation dependent granule-external membrane protein|platelet alpha-granule membrane protein
Swissprots	P16109 Q8IVD1 Q5R344
Accessions	AAA35910 AAC31762 AAN06828 EAW90850 EAW90851 EAW90852 EAW90853 EAW90854 P16109 AK312884 BAG35732 AY367063 AAQ67703 BC028067 AAH28067 BC068533 AAH68533 DA926598 DA994564 M25322 AAA35911 XM_005245435 XP_005245492 XM_005245436 XP_005245493 XM_005245438 XP_005245495 XM_005245439 XP_005245496 XM_005245440 XP_005245497 NM_003005 NP_002996
Function	Ca(2+)-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. Mediates the interaction of activated endothelial cells or platelets with leukocytes. The ligand recognized is sialyl-Lewis X. Mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with PSGL1. {ECO:0000269|PubMed:7585950}.
Subcellular Location	Membrane; Single-pass type I membrane protein.
Tissue Specificity	Stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. Upon cell activation by agonists, P-selectin is transported rapidly to the cell surface.
Top Pathways	Cell adhesion molecules (CAMs), Staphylococcus aureus infection, Malaria

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

CD62P protein (Fc Chimera Active) - ab83583 from Abcam Category Protein Prices $302.00 Sizes 25 µg Source HEK 293 cells Species Human

Human CD62P full length protein - ab132940 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

Human CD62P protein fragment - ab53386 from Abcam Category Protein Prices $192.00 Sizes 10 µg Source E. coli Species Human

Human CD62P protein fragment - ab83582 from Abcam Category Protein Prices $297.00 Sizes 5 µg Source HEK 293 cells Species Human

Recombinant Human P-Selectin/CD62P Protein - H00006403-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human P-Selectin/CD62P Protein - H00006403-G01 from Novus Biologicals Category Protein Prices $569.00 Sizes 10 µg Source Wheat Germ Species Human

Recombinant Human P-Selectin/CD62P, CF - ADP3-050 from R&D Systems Category Protein Source Chinese Hamster Ovary cell line, CHO-derived, Trp42-Ala771

Recombinant Human P-Selectin/CD62P, CF - ADP3-200 from R&D Systems Category Protein Source Chinese Hamster Ovary cell line, CHO-derived, Trp42-Ala771

Recombinant Human P-Selectin/CD62P Fc Chimera, CF - 137-PS-050 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived

P Selectin Protein (OPPA01294) - OPPA01294 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 2 µg Source E. Coli

Human SELP protein (His Tag) - orb139639 from Biorbyt Category Protein Prices $298.00, $400.00 Sizes 50 μg, 100 μg Source Human Cells Species Human

Human CD62P protein - orb81286 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Species Human

Human SELP protein - orb139638 from Biorbyt Category Protein Prices $298.00, $400.00 Sizes 50 μg, 100 μg Source Human Cells Species Human

P-Selectin Blocking Peptide - 33R-10845 from Fitzgerald Category Peptide Prices $145.00 Sizes 50 µg

CD62P Blocking Peptide - abx161063 from Abbexa Category Peptide Species Human, Mouse, Rat, Chicken, Rabbit, Sheep

Human Selectin, Platelet Protein - abx069010 from Abbexa Category Protein Source E.coli Species Human

Human Selectin, Platelet Protein - abx069013 from Abbexa Category Protein Source E.coli Species Human

CD62P / P-Selectin - H00006403-G01 from Acris Antibodies Category Protein Prices $550.00 Sizes 10 µg Species Human

CD62P / P-Selectin - H00006403-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

CD62P / P-Selectin - H00006403-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

P-selectin, Human Recombinant - 228-11332-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Source Escherichia Coli. Species Human

Recombinant Human P-Selectin - 228-11332-2 from RayBiotech Category Protein Prices $189.00 Sizes 2 µg Source Escherichia Coli. Species Human

Recombinant Human P-Selectin - 228-11332-3 from RayBiotech Category Protein Source Escherichia Coli. Species Human

Selectin, Platelet (SELP), Human - 20-6832 from ARP American Research Products Category Protein Prices $289.00 Sizes 50 µg Source E.coli Species Human

SELP fusion protein - ag4124 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

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