CELF6

Gene Symbol	CELF6
Entrez Gene	60677
Alt Symbol	BRUNOL6
Species	Human
Gene Type	protein-coding
Description	CUGBP, Elav-like family member 6
Other Description	Bruno -like 6, RNA binding protein\|CELF-6\|CUG-BP and ETR-3 like factor 6\|CUG-BP- and ETR-3-like factor 6\|CUGBP Elav-like family member 6\|RNA-binding protein BRUNOL-6\|bruno-like 6, RNA binding protein\|bruno-like protein 6
Swissprots	Q6ZNJ7 B4DJB6 B4DG28 Q6PII4 Q8N607 Q96J87
Accessions	EAW77900 EAW77901 Q96J87 AF401233 AAK95615 AF425606 AAL34513 AK124858 BAG54108 AK131098 BAC85148 AK294382 BAG57639 AK296004 BAG58778 BC030835 AAH30835 BC033838 AAH33838 BM681937 BM930660 BU732838 CA393931 DC368992 NM_001172684 NP_001166155 NM_001172685 NP_001166156 NM_052840 NP_443072
Function	RNA-binding protein implicated in the regulation of pre- mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of TNNT2 in a muscle-specific splicing enhancer (MSE)-dependent manner. Promotes also exon exclusion of INSR pre-mRNA. {ECO:0000269\|PubMed:14761971}.
Subcellular Location	Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}.
Tissue Specificity	Expressed mainly in kidney, brain and testis and present in other tissues albeit at lower levels. Also expressed in fetal kidney. {ECO:0000269\|PubMed:14761971}.

CELF6 (N-14) - sc-164028 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

CELF6 (Q-14) - sc-164029 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

Anti-BRUNOL6 antibody - ab80314 from Abcam

Prices	$370.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-BRUNOL6 antibody (ab80314) at 1 µg/ml + HepG2 cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-BRUNOL6 antibody - ab169494 from Abcam

Prices	$370.00
Sizes	50 µl
Host	Mouse
Clonality	Polyclonal

All lanes : Anti-BRUNOL6 antibody (ab169494) at 1/500 dilutionLane 1 : BRUNOL6 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.developed using the ECL technique

Anti-BRUNOL6 antibody [EPR10155] - ab173282 from Abcam

Prices	$357.00
Sizes	100 µl
Host	Rabbit
Clonality	Monoclonal
Clone	EPR10155

All lanes : Anti-BRUNOL6 antibody [EPR10155] (ab173282) at 1/1000 dilutionLane 1 : Human fetal kidney lysateLane 2 : Human fetal brain lysateLane 3 : HepG2 cell lysateLane 4 : 293T cell lysateLysates/proteins at 10 µg per lane.SecondaryGoat anti-rabbit HRP at 1/2000 dilutiondeveloped using the ECL technique

Anti-BRUNOL6 antibody - N-terminal - ab170449 from Abcam

Prices	$370.00
Sizes	400 µl
Host	Rabbit
Clonality	Polyclonal

Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human kidney tissue labeling BRUNOL6 with ab170449 at 1/50 dilution, followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-BRUNOL6 / CELF6 Antibody (aa46-74, AP) - LS-C233211 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-BRUNOL6 / CELF6 Antibody (aa46-74, APC) - LS-C233212 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-BRUNOL6 / CELF6 Antibody (aa46-74, Biotin) - LS-C233213 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-BRUNOL6 / CELF6 Antibody (aa46-74, FITC) - LS-C233215 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-BRUNOL6 / CELF6 Antibody (aa46-74, Azide-free, HRP) - LS-C249535 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-BRUNOL6 / CELF6 Antibody (aa46-74, PE) - LS-C233216 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-BRUNOL6 / CELF6 Antibody (aa53-82) - LS-C319886 from LifeSpan Bioscience

Prices	$345.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-BRUNOL6 / CELF6 Antibody (aa254-303) - LS-C82435 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

HepG2 cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-BRUNOL6 / CELF6 Antibody (aa46-74) - LS-C156865 from LifeSpan Bioscience

Prices	$295.00
Sizes	400 µl
Host	Rabbit
Clonality	Polyclonal

BRUNOL6 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human kidney tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

BRUNOL6 Antibody - NBP2-31562 from Novus Biologicals

Prices	$419.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

BRUNOL6 Antibody - NBP2-32050 from Novus Biologicals

Prices	$419.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Immunohistochemistry: BRUNOL6 Antibody [NBP2-32050] - Staining of human bone marrow shows strong nuclear and cytoplasmic positivity in hematopoietic cells.

BRUNOL6 Antibody - NBP1-57256 from Novus Biologicals

Prices	$139.00, $329.00
Sizes	20 µl, 100 µl
Host	Rabbit
Clonality	Polyclonal

BRUNOL6 Antibody - H00060677-B01 from Novus Biologicals

Prices	$349.00
Sizes	50 µl
Host	Mouse
Clonality	Polyclonal

Western Blot: BRUNOL6 Antibody [H00060677-B01] - analysis of BRUNOL6 expression in transfected 293T cell line by BRUNOL6 MaxPab polyclonal antibody. Lane 1: BRUNOL6 transfected lysate (52.91 KDa). Lane 2: Non-transfected lysate.

Anti-CELF6 antibody produced in rabbit - HPA053526 from Sigma-Aldrich

Prices	$429.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

<B>Immunohistochemistry</B><BR/>Anti-CELF6: <B>Cat. No. HPA053526</B>: Immunohistochemical staining of Human testis shows distinct positivity in spermatozoa.

Anti-BRUNOL6 antibody produced in rabbit - SAB2100225 from Sigma-Aldrich

Prices	$347.50
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

<B>Immunoblotting</B><BR/>Anti-BRUNOL6: <B>Cat. No.SAB2100225</B>: BRUNOL6 in HepG2 cell lysate with BRUNOL6 antibody at 1.0 μg/mL.

Anti-CELF6 antibody produced in rabbit - HPA046985 from Sigma-Aldrich

Prices	$429.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

<B>Immunohistochemistry</B><BR/>Anti-CELF6: <B>Cat. No. HPA046985</B>: Immunohistochemical staining of Human bone marrow shows strong nuclear and cytoplasmic positivity in hematopoietic cells.

ANTI-BRUNOL6 (N-TERM) antibody produced in rabbit - SAB1303450 from Sigma-Aldrich

Prices	$326.50
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

<B>Immunohistochemistry</B><BR/>BRUNOL6 (N-term): <B>Cat. No. SAB1303450</B>: BRUNOL6 in Human kidney tissue with BRUNOL6 antibody (N-term) at 12.5 μg/mL.

BRUNOL6 antibody - middle region (ARP41078_P050) - ARP41078_P050 from Aviva Systems Biology

Prices	$289.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

BRUNOL6-Antibody-N-term - AP11714a from Abgent, a WuXi AppTec company

Prices	$99.00, $295.00
Sizes	80 µl, 400 µl
Host	Rabbit
Clonality	Polyclonal

BRUNOL6 Antibody (N-term) (Cat. #AP11714a)immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of BRUNOL6 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

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