GEMIN7

Gene Symbol	GEMIN7
Entrez Gene	79760
Alt Symbol	SIP3
Species	Human
Gene Type	protein-coding
Description	gem (nuclear organelle) associated protein 7
Other Description	gem-associated protein 7|gemin 7|gemin-7
Swissprots	Q9H840 Q6IA34
Accessions	CAE91216 EAW57321 Q9H840 AK024018 BAB14780 AY114106 AAM44083 BC007793 AAH07793 BU602037 CB148876 CR457321 CAG33602 W35331 XM_005259262 XP_005259319 XM_005259263 XP_005259320 XM_005259264 XP_005259321 XM_011527319 XP_011525621 NM_001007269 NP_001007270 NM_001007270 NP_001007271 NM_024707 NP_078983
Function	The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus. {ECO:0000269|PubMed:12065586, ECO:0000269|PubMed:18984161}.
Subcellular Location	Nucleus, nucleoplasm {ECO:0000269|PubMed:12065586}. Nucleus, gem {ECO:0000269|PubMed:12065586}. Cytoplasm {ECO:0000269|PubMed:12065586}. Note=Found both in the nucleoplasm and in nuclear bodies called gems (Gemini of Cajal bodies) that are often in proximity to Cajal (coiled) bodies. Also found in the cytoplasm.
Top Pathways	RNA transport

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Gemin 7 full length protein - ab164102 from Abcam Category Protein Source Wheat germ Species Human

Human Gemin 7 peptide - ab33357 from Abcam Category Peptide

Human Gemin 7 protein fragment - ab164103 from Abcam Category Protein Source Wheat germ Species Human

Recombinant Human Gemin 7 Protein - H00079760-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human Gemin 7 Protein - H00079760-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Human GEMIN7 protein - orb246626 from Biorbyt Category Protein Prices $213.00, $408.00, $680.00, $1,122.00, $1,777.00 Sizes 10 μg, 50 μg, 200 μg, 500 μg, 1 mg Species Human

Gemin-7 - H00079760-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Gemin-7 - H00079760-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Gemin-7 - H00079760-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Gemin-7 - H00079760-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

GEMIN7 fusion protein - ag0976 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant human Gem-associated protein 7 - CSB-EP862039HU CSB-BP862039HU CSB-MP862039HU from Cusabio Category Protein Source E.coli or Baculovirus or Mammalian cell Species Human

Recombinant human Gem-associated protein 7 - CSB-EP862039HU from Cusabio Category Protein Source E.coli Species Human

Recombinant Human Gem-associated protein 7(GEMIN7) - CSB-YP862039HU CSB-BP862039HU CSB-MP862039HU from Cusabio Category Protein Source Yeast or Baculovirus or Mammalian cell Species Human

Gemin-7 (full length, N-term HIS tag, transcript variant 2) - TP760735 from Acris Antibodies Category Protein Prices $199.00 Sizes 50 µg Source E. coli Species Human

Gemin-7 (full length, N-term HIS tag, transcript variant 1) - TP760747 from Acris Antibodies Category Protein Prices $199.00 Sizes 50 µg Source E. coli Species Human

GEMIN7 Peptide, Human - M34GP06208H from Creative Peptides Category Peptide Source Synthetic. Species Human

GEMIN7 Recombinant Protein (OPCA02457) - OPCA02457 from Aviva Systems Biology Category Protein Prices $250.00 Sizes 50 µg Source Human

Gem-associated protein 7, Recombinant Protein - MBS1455894 from MyBioSource Category Protein Prices $190.00, $460.00, $750.00, $870.00, $1,090.00, $1,090.00, $1,180.00, $1,265.00, $1,720.00, $1,720.00 Sizes 50 µg (E-Coli), 200 µg (E-Coli), 500 µg (E-Coli), 50 µg (Baculovirus), 50 µg (Mammalian-Cell), 500 µg (Yeast), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell

Recombinant human Gem-associated protein 7 - AP71515 from Signalway Antibody Category Protein Prices $260.00, $735.00, $1,240.00, $1,975.00 Sizes 50 µg, 200 µg, 500 µg, 1 mg Source E.coli Species Human

Gemin 7 Recombinant Protein Antigen - NBP2-58154PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Gem-associated protein 7, Recombinant Protein - MBS9421378 from MyBioSource Category Protein Prices $280.00, $665.00, $1,080.00, $1,690.00 Sizes 50 µg, 200 µg, 500 µg, 1 mg Source E Coli Species Human

Recombinant Human GEMIN7 Protein (1-131 aa), GST-tagged - GEMIN7-1115H from Creative Biomart Category Protein Source E. coli Species Human

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