TFRC

Gene Symbol	TFRC
Entrez Gene	7037
Alt Symbol	CD71, T9, TFR, TFR1, TR, TRFR, p90
Species	Human
Gene Type	protein-coding
Description	transferrin receptor
Other Description	transferrin receptor (p90, CD71)|transferrin receptor protein 1
Swissprots	Q9UDF9 Q1HE24 Q9UCN0 Q59G55 Q9UCU5 D3DXB0 P02786 Q9UK21
Accessions	AAF04564 ABF47088 EAW53670 EAW53671 EAW53672 EAW53673 P02786 AB209254 BAD92491 AK291723 BAF84412 AK294758 BAH11872 AK309923 BC001188 AAH01188 BX537966 CAD97930 CK724857 DA460386 DQ892859 ABM83785 DQ896108 ABM87107 DT219054 M11507 AAA61153 X01060 CAA25527 XM_011513112 XP_011511414 NM_001128148 NP_001121620 NM_003234 NP_003225
Function	Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site. {ECO:0000250, ECO:0000269|PubMed:3568132}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:17081065}; Single-pass type II membrane protein {ECO:0000269|PubMed:17081065}. Melanosome {ECO:0000269|PubMed:17081065}. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Top Pathways	Hematopoietic cell lineage, Endocytosis, Phagosome

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CD71 / Transferrin Receptor ELISA Kit (Sandwich ELISA) - LS-F6227 from LifeSpan Bioscience Category ELISA Kit Prices $690.00 Sizes 1 plate Sensitivity 0.144 ng/ml Range 0.625-40 ng/ml

Rat CD71 / Transferrin Receptor ELISA Kit (Sandwich ELISA) - LS-F6637 from LifeSpan Bioscience Category ELISA Kit Prices $740.00 Sizes 1 plate Sensitivity 0.625 ng/ml Range 0.625-40 ng/ml

Mouse/Human CD71 / Transferrin Receptor ELISA Kit (Cell-Based ELISA) - LS-F1872 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 0.625-40 ng/ml

Mouse CD71 / Transferrin Receptor ELISA Kit (Sandwich ELISA) - LS-F9235 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 0.313 ng/ml Range 0.625-40 ng/ml

Pig CD71 / Transferrin Receptor ELISA Kit (Sandwich ELISA) - LS-F12727 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 1.56 Range 0.625-40 ng/ml

Human sTfR Quantikine IVD ELISA Kit - DTFR1 from R&D Systems Category ELISA Kit Prices $509.00 Sizes 1 kit Sensitivity 0.5 nmol/L Range 3.0 - 80 nmol/L (Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma)

Human TfR DuoSet ELISA - DY2474 from R&D Systems Category ELISA Kit Prices $649.00 Sizes 1 kit (for 15 Plates) Range 78.10 - 5,000 pg/mL

Transferrin Receptor, TFR/CD71, Human, ELISA Kit - E-EL-H2345 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 0.938 Range 1.563-100ng/mL

Transferrin Receptor (TFR), Human, ELISA Kit - SEB171Hu from ARP American Research Products Category ELISA Kit Prices $685.00 Sizes 96 t Sensitivity 0.58ng/mL Range 1.56-100ng/mL

Transferrin receptor protein 1 (TFRC), Human, ELISA Kit - E01T0683 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Transferrin receptor protein 1, TFRC, Human, ELISA Kit - E0809h from ARP American Research Products Category ELISA Kit Prices $476.00 Sizes 96 t Range 3.12-200 ng/mL

Transferrin Receptor, Human, ELISA Kit - E01T0137 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 1.0ng/ml Range 2.5-50ng/ml

Transferrin Receptor, TFR, Mouse, ELISA Kit - E-EL-M1186 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 0.375 Range 0.625-40ng/mL

Transferrin Receptor, TFR, Rat, ELISA Kit - E-EL-R1009 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 0.188 Range 0.313-20ng/mL

Transferrin Receptor, TFR/CD71, Rabbit, ELISA Kit - E-EL-RB1110 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Transferrin Receptor, TFR/CD71, Chicken, ELISA Kit - E-EL-Ch0378 from ARP American Research Products Category ELISA Kit Prices $445.50 Sizes 96 t

Transferrin Receptor, TFR/CD71, Porcine, ELISA Kit - E-EL-P1850 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Transferrin Receptor, TFR/CD71, Guinea Pig, ELISA Kit - E-EL-GP0187 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Transferrin Receptor, TFR/CD71, Monkey, ELISA Kit - E-EL-MK1179 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Custom Human TfR ELISA - ELH-TfR from RayBiotech Category ELISA Kit Prices $615.00, $1,107.00, $2,460.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit

Human TFR ELISA Kit - HT0144 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Anserine TFR ELISA Kit - AT0144 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Transferrin Receptor, ELISA Kit - MBS726027 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transferrin Receptor, ELISA Kit - MBS738334 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 1.0 ng/mL.

Transferrin Receptor, ELISA Kit - MBS742435 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Search more