THBD

Gene Symbol	THBD
Entrez Gene	7056
Alt Symbol	AHUS6, BDCA3, CD141, THPH12, THRM, TM
Species	Human
Gene Type	protein-coding
Description	thrombomodulin
Other Description	CD141 antigen|fetomodulin
Swissprots	Q8IV29 P07204 Q9UC32
Accessions	AAA61175 AAM03232 BAA00149 EAX10172 P07204 AI285986 AK091934 AK123557 BAG53913 BC035602 AAH35602 BC053357 AAH53357 BG771668 M16552 AAB59508 X05495 CAA29045 NM_000361 NP_000352
Function	Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated.
Subcellular Location	Membrane; Single-pass type I membrane protein.
Tissue Specificity	Endothelial cells are unique in synthesizing thrombomodulin.
Top Pathways	Complement and coagulation cascades

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Thrombomodulin (CD141) Human ELISA Kit - ab46508 from Abcam Category ELISA Kit Prices $489.00, $734.00 Sizes 1 x 96 tests, 2 x 96 tests Sensitivity < 0.31 ng/ml Range 0.625 ng/ml - 20 ng/ml

Thrombomodulin Human ELISA Set (without plates) - ab47358 from Abcam Prices $557.00, $636.00, $765.00 Sizes 5 x 96 tests, 10 x 96 tests, 15 x 96 tests Sensitivity < 0.38 ng/ml Range 0.625 ng/ml - 20 ng/ml

Human THBD / Thrombomodulin ELISA Kit - RAB0739 from Sigma-Aldrich Category ELISA Kit Prices $637.00 Sizes 1 kt

Human THBD / CD141 / Thrombomodulin ELISA Kit (Sandwich ELISA) - LS-F5565 from LifeSpan Bioscience Category ELISA Kit Prices $650.00 Sizes 1 plate Sensitivity 18.24 pg/ml Range 32-2000 pg/ml

Rat THBD / CD141 / Thrombomodulin ELISA Kit (Sandwich ELISA) - LS-F5567 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 0.56 ng/ml Range 32-2000 pg/ml

Mouse THBD / CD141 / Thrombomodulin ELISA Kit (Sandwich ELISA) - LS-F5566 from LifeSpan Bioscience Category ELISA Kit Prices $670.00 Sizes 1 plate Sensitivity 31.25 pg/ml Range 32-2000 pg/ml

Dog THBD / CD141 / Thrombomodulin ELISA Kit (Sandwich ELISA) - LS-F5315 from LifeSpan Bioscience Category ELISA Kit Prices $650.00 Sizes 1 plate Sensitivity 5.8 pg/ml Range 32-2000 pg/ml

Pig THBD / CD141 / Thrombomodulin ELISA Kit (Sandwich ELISA) - LS-F5316 from LifeSpan Bioscience Category ELISA Kit Prices $780.00 Sizes 1 plate Sensitivity 0.29 ng/ml Range 32-2000 pg/ml

Rabbit THBD / CD141 / Thrombomodulin ELISA Kit (Sandwich ELISA) - LS-F5393 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 0.156 ng/ml Range 32-2000 pg/ml

Human THBD / CD141 / Thrombomodulin ELISA Kit (Sandwich ELISA) - LS-F720 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 32-2000 pg/ml

Mouse THBD / CD141 / Thrombomodulin ELISA Kit (Sandwich ELISA) - LS-F2836 from LifeSpan Bioscience Category ELISA Kit Prices $530.00 Sizes 1 plate Sensitivity 10 pg/ml Range 32-2000 pg/ml

Human THBD / CD141 / Thrombomodulin ELISA Kit (Sandwich ELISA) - LS-F2756 from LifeSpan Bioscience Category ELISA Kit Prices $530.00 Sizes 1 plate Sensitivity 62.5 pg/ml Range 32-2000 pg/ml

Human THBD / CD141 / Thrombomodulin ELISA Kit (Sandwich ELISA) - LS-F12846 from LifeSpan Bioscience Category ELISA Kit Prices $530.00 Sizes 1 plate Sensitivity 0.156 Range 32-2000 pg/ml

Human Thrombomodulin/BDCA-3 Quantikine ELISA Kit - DTHBD0 from R&D Systems Category ELISA Kit Prices $519.00 Sizes 1 kit Sensitivity 27 pg/mL Range 62.5 - 4,000 pg/mL (Cell Culture Supernates, Cell Lysates, Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma, Urine)

Human Thrombomodulin/BDCA-3 DuoSet ELISA - DY3947 from R&D Systems Category ELISA Kit Prices $649.00 Sizes 1 kit (for 15 Plates) Range 31.20 - 2,000 pg/mL

Mouse Thrombomodulin/BDCA-3 DuoSet ELISA - DY3894 from R&D Systems Category ELISA Kit Prices $649.00 Sizes 1 kit (for 15 Plates) Range 93.80 - 6,000 pg/mL

Mouse Thrombomodulin/BDCA-3 Quantikine ELISA Kit - MTHBD0 from R&D Systems Category ELISA Kit Prices $479.00 Sizes 1 kit Sensitivity 19.1 pg/mL Range 46.9 - 3,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Urine)

Quantikine Immunoassay Control Set 839 Human Thrombomodulin - QC169 from R&D Systems Category ELISA Kit Prices $125.00 Sizes 1 each

Thrombomodulin ELISA Kit (Human) : 96 Wells (OKAG00252) - OKAG00252 from Aviva Systems Biology Category ELISA Kit Prices $390.00 Sizes 96 wells Sensitivity 32 pg/mL Range 32-2,000 pg/mL

Mouse CD141 ELISA Kit - orb219613 from Biorbyt Category ELISA Kit Prices $706.00 Sizes 96 test Sensitivity 10 pg/ml Range 62.5 pg/ml-4000 pg/ml

Human CD141 ELISA Kit - abx056065 from Abbexa Category ELISA Kit

Coagulation Factor II (F2), Human, ELISA Kit - SEA820Hu from ARP American Research Products Category ELISA Kit Prices $650.00 Sizes 96 t Sensitivity 0.29ng/mL Range 0.78 -50ng/mL

Thrombomodulin (TM), Human, ELISA Kit - SEA529Hu from ARP American Research Products Category ELISA Kit Prices $650.00 Sizes 96 t Sensitivity 41.25pg/mL Range 93.75-6,000pg/mL

Thrombomodulin, Human, ELISA Kit - E01T0229 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 1.0pg/ml Range 250-5000pg/ml

Thrombomodulin, THBD, Human, ELISA Kit - E0529h from ARP American Research Products Category ELISA Kit Prices $476.00 Sizes 96 t Range 0.156-10 ng/mL

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