THBD

Gene Symbol THBD
Entrez Gene 7056
Alt Symbol AHUS6, BDCA3, CD141, THPH12, THRM, TM
Species Human
Gene Type protein-coding
Description thrombomodulin
Other Description CD141 antigen|fetomodulin
Swissprots Q8IV29 P07204 Q9UC32
Accessions AAA61175 AAM03232 BAA00149 EAX10172 P07204 AI285986 AK091934 AK123557 BAG53913 BC035602 AAH35602 BC053357 AAH53357 BG771668 M16552 AAB59508 X05495 CAA29045 NM_000361 NP_000352
Function Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated.
Subcellular Location Membrane; Single-pass type I membrane protein.
Tissue Specificity Endothelial cells are unique in synthesizing thrombomodulin.
Top Pathways Complement and coagulation cascades

THBD - MBS1267402 from MyBioSource

Prices $630.00
Sizes 10ug plasmid + 200ul glycerol stock
Species Human
Accession BC053357

Human THBD cDNA clone(NM_000361.2) - CDFH019564 from Creative Biomart

Species Human
Accession NM_000361.2

Human THBD ORF Clone(NM_000361.2) - CDCR336020 from Creative Biomart

Species Human
Accession NM_000361.2

Human THBD ORF Clone(NM_000361.2) - CDCR336021 from Creative Biomart

Species Human
Accession NM_000361.2

Human THBD ORF Clone(NM_000361.2) - CDCL178388 from Creative Biomart

Species Human
Accession NM_000361.2

human THBD ORF clone - CDCH090780 from Creative Biomart

Species Human
Accession NM_000361

human THBD ORF clone - CDCH090781 from Creative Biomart

Species Human
Accession NM_000361

human THBD ORF clone - CDCH090782 from Creative Biomart

Species Human
Accession NM_000361

human THBD ORF clone - CDCH090783 from Creative Biomart

Species Human
Accession NM_000361

human THBD ORF clone (NM_000361.2) - CDCH090780 from Creative biogene

Species Human

Human THBD ORF Clone (BC053357) - CDCS405604 from Creative biogene

Species Human
Accession P07204

Human THBD cDNA Clone(NM_000361.2) - CDFH019564 from Creative biogene

Species Human

Human Thrombomodulin/BDCA-3 (NP_000352) VersaClone cDNA - RDC1805 from R&D Systems

Prices $199.00
Sizes 10 µg
Species Human
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