FURIN

Gene Symbol	FURIN
Entrez Gene	5045
Alt Symbol	FUR, PACE, PCSK3, SPC1
Species	Human
Gene Type	protein-coding
Description	furin (paired basic amino acid cleaving enzyme)
Other Description	FES upstream region|dibasic processing enzyme|furin|furin, membrane associated receptor protein|paired basic amino acid residue-cleaving enzyme|proprotein convertase subtilisin/kexin type 3
Swissprots	Q14336 Q9UCZ5 Q6LBS3 P09958
Accessions	CAA00605 CAA27860 CAA33745 EAX02111 EAX02112 P09958 AI051906 AL110107 AL555508 BC008295 BC012181 AAH12181 BM043834 BP282138 BP283962 S65442 AAB28140 X17094 CAA34948 NM_001289823 NP_001276752 NM_001289824 NP_001276753 NM_002569 NP_002560
Function	Furin is likely to represent the ubiquitous endoprotease activity within constitutive secretory pathways and capable of cleavage at the RX(K/R)R consensus motif. {ECO:0000269|PubMed:7690548}.
Subcellular Location	Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein. Cell membrane; Single-pass type I membrane protein. Note=Shuttles between the trans-Golgi network and the cell surface. Propeptide cleavage is a prerequisite for exit of furin molecules out of the endoplasmic reticulum (ER). A second cleavage within the propeptide occurs in the trans Golgi network (TGN), followed by the release of the propeptide and the activation of furin.
Tissue Specificity	Seems to be expressed ubiquitously.
Top Pathways	Influenza A

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Furin Human ELISA Kit - ab113322 from Abcam Category ELISA Kit Prices $749.00 Sizes 1 x 96 tests Sensitivity < 15 pg/ml Range 13.72 pg/ml - 10000 pg/ml

Human FURIN ELISA Kit (Sandwich ELISA) - LS-F2755 from LifeSpan Bioscience Category ELISA Kit Prices $530.00 Sizes 1 plate Sensitivity 10 pg/ml Range 13.71-3333 pg/ml

Human FURIN ELISA Kit (Sandwich ELISA) - LS-F7234 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.061 ng/ml Range 13.71-3333 pg/ml

Human FURIN ELISA Kit (Sandwich ELISA) - LS-F92 from LifeSpan Bioscience Category ELISA Kit Prices $620.00, $1,090.00, $2,380.00 Sizes 1 plate, 2 plate, 5 plate Sensitivity 13.71 pg/ml Range 13.71-3333 pg/ml

Rat FURIN ELISA Kit (Sandwich ELISA) - LS-F9935 from LifeSpan Bioscience Category ELISA Kit Prices $780.00 Sizes 1 plate Sensitivity 0.053 ng/ml Range 13.71-3333 pg/ml

Human Furin ELISA Kit - RAB0198 from Sigma-Aldrich Category ELISA Kit Prices $608.00 Sizes 1 kt

Human Furin DuoSet ELISA - DY1503 from R&D Systems Category ELISA Kit Prices $649.00 Sizes 1 kit (for 15 Plates) Range 0.312 - 20 ng/mL

Human Furin ELISA Kit - abx151602 from Abbexa Category ELISA Kit Sensitivity 0.057 ng/ml Range 0.156 ng/ml - 10 ng/ml

Human FURIN ELISA Kit - abx056166 from Abbexa Category ELISA Kit

Furin (FUR), Human, ELISA Kit - SEC494Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.055ng/mL Range 0.156-10ng/mL

Furin (FURIN), Human, ELISA Kit - CSB-EL009068HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Furin, Human, ELISA Kit - PB-0916 from ARP American Research Products Category ELISA Kit Prices $418.00 Sizes 96 t Sensitivity < 10 pg/ml Range 312pg/ml-20,000pg/ml

FURIN (Human) ELISA Kit - KA1859 from Acris Antibodies Category ELISA Kit Prices $780.00 Sizes 1 kit

Human Furin ELISA - ELH-Furin from RayBiotech Category ELISA Kit Prices $560.00, $1,008.00, $2,241.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit Sensitivity 15 pg/ml Range 15 pg/ml - 10000 pg/ml

Furin, ELISA Kit - MBS105531 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Furin, ELISA Kit - MBS075611 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Furin, ELISA Kit - MBS079730 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

FURIN, ELISA Kit - MBS824702 from MyBioSource Category ELISA Kit Prices $470.00 Sizes 96 tests Sensitivity 10 pg/ml Range 312 pg/ml - 20000 pg/ml

Furin, ELISA Kit - MBS176510 from MyBioSource Category ELISA Kit Prices $425.00 Sizes 1x96 wells Sensitivity < 10pg/ml Range 312pg/ml-20,000pg/ml

Furin, ELISA Kit - MBS081812 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Furin, ELISA Kit - MBS074932 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Furin, ELISA Kit - MBS048825 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1ng/ml Range 0.25ng/ml-8ng/ml

Furin, ELISA Kit - MBS070627 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Furin (FUR), ELISA Kit - MBS2020631 from MyBioSource Category ELISA Kit Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 0.061ng/mL. Range 0.156-10ng/mL

Furin (FUR), ELISA Kit - MBS2024952 from MyBioSource Category ELISA Kit Prices $405.00, $605.00, $820.00, $3,375.00, $6,125.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 0.053ng/mL. Range 0.156-10ng/mL

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