FURIN

Gene Symbol	FURIN
Entrez Gene	5045
Alt Symbol	FUR, PACE, PCSK3, SPC1
Species	Human
Gene Type	protein-coding
Description	furin (paired basic amino acid cleaving enzyme)
Other Description	FES upstream region|dibasic processing enzyme|furin|furin, membrane associated receptor protein|paired basic amino acid residue-cleaving enzyme|proprotein convertase subtilisin/kexin type 3
Swissprots	Q14336 Q9UCZ5 Q6LBS3 P09958
Accessions	CAA00605 CAA27860 CAA33745 EAX02111 EAX02112 P09958 AI051906 AL110107 AL555508 BC008295 BC012181 AAH12181 BM043834 BP282138 BP283962 S65442 AAB28140 X17094 CAA34948 NM_001289823 NP_001276752 NM_001289824 NP_001276753 NM_002569 NP_002560
Function	Furin is likely to represent the ubiquitous endoprotease activity within constitutive secretory pathways and capable of cleavage at the RX(K/R)R consensus motif. {ECO:0000269|PubMed:7690548}.
Subcellular Location	Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein. Cell membrane; Single-pass type I membrane protein. Note=Shuttles between the trans-Golgi network and the cell surface. Propeptide cleavage is a prerequisite for exit of furin molecules out of the endoplasmic reticulum (ER). A second cleavage within the propeptide occurs in the trans Golgi network (TGN), followed by the release of the propeptide and the activation of furin.
Tissue Specificity	Seems to be expressed ubiquitously.
Top Pathways	Influenza A

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Dibasic processing enzyme Gene - orb90744 from Biorbyt Prices $264.00 Sizes 10 μg Species Human

Human FURIN cDNA clone(NM_002569.2) - CDFH007172 from Creative Biomart Species Human Accession NM_002569.2

Human Furin ORF clone(NM_002569.2) - CDCL184330 from Creative Biomart Species Human Accession NM_002569.2

Human FURIN ORF Clone(NM_002569.2) - CDCR283532 from Creative Biomart Species Human Accession NM_002569.2

Human FURIN ORF Clone(NM_002569.2) - CDCR283533 from Creative Biomart Species Human Accession NM_002569.2

Human FURIN ORF Clone(NM_002569.2) - CDCR283534 from Creative Biomart Species Human Accession NM_002569.2

Human FURIN ORF Clone(NM_002569.2) - CDCL164086 from Creative Biomart Species Human Accession NM_002569.2

Mouse FURIN ORF clone - CDCL109779 from Creative Biomart Species Human Accession NM_002569

Mouse FURIN ORF clone - CDCL109780 from Creative Biomart Species Human Accession NM_002569

Human Furin Gene ORF cDNA clone in cloning vector - HG10141-M from Sino Biological Species Human

Human Furin Gene ORF cDNA clone expression plasmid, N-His tag - HG10141-NH from Sino Biological Species Human

Human Furin Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG10141-ACR from Sino Biological Species Human

Human Furin ORF mammalian expression plasmid, Flag tag - HG10141-M-F from Sino Biological Species Human Accession NM_002569.2

Human Furin Gene cDNA Clone (full-length ORF Clone), expression ready, untagged - HG10141-M-N from Sino Biological Species Human Accession NM_002569.2

Human Furin Gene ORF cDNA clone expression plasmid - HG10141-UT from Sino Biological Species Human

Human Furin Gene ORF cDNA clone expression plasmid, C-HA tag - HG10141-CY from Sino Biological Species Human

Human Furin Gene ORF cDNA clone expression plasmid, C-His tag - HG10141-M-H from Sino Biological Species Human

Human Furin Gene ORF cDNA clone expression plasmid, C-His tag - HG10141-CH from Sino Biological Species Human

Human Furin Gene ORF cDNA clone expression plasmid, N-Flag tag - HG10141-NF from Sino Biological Species Human

Human Furin Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10141-CF from Sino Biological Species Human

Human Furin Gene ORF cDNA clone expression plasmid, N-Myc tag - HG10141-NM from Sino Biological Species Human

Human Furin Gene ORF cDNA clone expression plasmid, N-HA tag - HG10141-NY from Sino Biological Species Human

Human Furin Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG10141-ACG from Sino Biological Species Human

Human Furin Gene ORF cDNA clone expression plasmid, C-Myc tag - HG10141-CM from Sino Biological Species Human

Human Furin ORF clone(NM_002569.2) - CDCL184330 from Creative biogene Species Human

Search more